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For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
A variety of products designed for use in various PCR procedures. Includes dNTPs, enzymes, assays, arrays, master mixes, reagents, and kits. Products can be used for standard, real-time, direct, high fidelity, hot start, and long range PCR protocols.
The KRAS gene provides instructions for making a protein called K-Ras part of the RAS/MAPK pathway The protein relays signals from outside the cell to the cell s nucleus These signals instruct the cell to grow and divide (proliferate) or to mature and take on specialized functions (differentiate) The K-Ras protein is a GTPase which means it converts a molecule called GTP into another molecule called GDP In this way the K-Ras protein acts like a switch that is turned on and off by the GTP and GDP molecules KRAS is usually tethered to cell membranes because of the presence of an isoprene group on its C-terminus There are two protein products of the KRAS gene in mammalian cells that result from the use of alternative exon 4 (exon 4A and 4B respectively) K-Ras4A and K-Ras4B these proteins have different structure in their C-terminal region and use different mechanisms to localize to cellular membranes including the plasma membrane
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Inactive at room temperature Increased specificity This is the Hot-Start version of Choice-Taq™ DNA Polymerase that requires a pre-activation step at 95°C for 5 minutes in order to achieve a fully functional polymerase enzyme. The inactivity of the enzyme at room temperature increases the specificity of the enzyme for the desired template.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More