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Filtered Search Results
Medchemexpress LLC DLinDMA | 871258-12-7 | 99.49% | 616.06 | 100 MG
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DLinDMA, an ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. It is used for siRNA delivery. Its structure can be divided into three main regions: the hydrocarbon chains, the linker, and the headgroup.
- Ionizable cationic lipid
- Key lipid component of stable nucleic acid lipid particles (SNALPs)
- Used for siRNA delivery
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Medchemexpress LLC Fosmidomycin sodium salt | 66508-37-0 | 99.7% | 205.08 | 50 MG
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Fosmidomycin sodium salt is a phosphonic acid antibiotic and an antimalarial agent, active against both Gram-negative and Gram-positive bacteria. It has shown effectiveness in in vivo studies, with animals treated intraperitoneally or orally becoming apparently free of parasites. Mice treated for 8 days were totally cured.
- Phosphonic acid antibiotic.
- Antimalarial agent.
- Active against both Gram-negative and Gram-positive bacteria.
- In vivo studies show that animals treated intraperitoneally with dosages >10 mg/kg are apparently free of parasites.
- In vivo studies show that animals treated orally with 50 or 100 mg/kg are apparently free of parasites.
- Mice treated with 30 mg/kg over an 8-day period were totally cured.
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Medchemexpress LLC Cd80-in-3 | 486449-65-4 | MFCD32701897 | 98.0% | 323.28 g/mol | C17H10FN3O3 | 100 MG
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CD80-IN-3 is a small-molecule inhibitor that blocks the CD80/CD28 interaction, showing in vitro potency (EC50 = 630 nM) and measurable binding affinity (Kd = 125 nM). It is supplied as a solid and is also available as a DMSO solution for assay use; intended for research use only.
- Potent CD80 inhibitor; inhibits CD80/CD28 interaction (EC50 = 630 nM).
- Measured binding affinity Kd = 125 nM.
- High purity solid suitable for biochemical and cellular assays (98.0%).
- Molecular weight 323.28 g/mol; molecular formula C17H10FN3O3.
- CAS number 486449-65-4 for unambiguous identification.
- Available in milligram quantities and solution formats for assay flexibility.
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eMolecules Medchem Express / Amifostine thiol / 10mg / 572596866 / HY-137864 / / 31098-42-7 / MFCD00296912 / 134.240 / C5H14N2S
Medchem Express / Amifostine thiol / 10mg / 572596866 / HY-137864 / / 31098-42-7 / MFCD00296912 / 134.240 / C5H14N2S
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eMolecules Medchem Express / 6-Mercaptopurine hydrate / 50mg / 446263309 / HY-13677A / / 6112-76-1 / MFCD03854445 / 170.190 / C5H6N4OS
Medchem Express / 6-Mercaptopurine hydrate / 50mg / 446263309 / HY-13677A / / 6112-76-1 / MFCD03854445 / 170.190 / C5H6N4OS
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Selleck Chemical LLC Poziotinib
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Poziotinib is an irreversible pan-HER inhibitor with IC50 of 3 2 nM 5 3 nM and 23 5 nM for HER1 HER2 and HER4 respectively Poziotinib also induces apoptosis and G1 cell cycle arrest Phase 2
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eMolecules Eltanexor (KPT-8602) | Selleck Chemicals | 1642300-52-4 | | 428.298 | C17H10F6N6O | | NC(=O)C(=Cn1cnc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cncnc1 | 5mg | 351295167
Eltanexor (KPT-8602) | Selleck Chemicals | 1642300-52-4 | | 428.298 | C17H10F6N6O | | NC(=O)C(=Cn1cnc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cncnc1 | 5mg | 351295167
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MACROCYCLICS GD-DO3A-BUTYLAMINE 100MG
NC2313459 GD-DO3A-BUTYLAMINE 100MG
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Medchemexpress LLC N-(4-mesitylthiazol-2-yl)benzamide | 1001753-24-7 | 99.5% | 322.42 | C19H18N2OS | 25 MG
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INH6 is a small-molecule Nek2/Hec1 inhibitor that inactivates Hec1/Nek2 function via protein degradation, leading to chromosome missegregation and cell death. It inhibits HeLa cell growth with an IC50 of 2.4 μM and produces mitotic defects and apoptosis in treated cells.
- Potent Nek2/Hec1 inhibition (IC50 2.4 μM).
- Inactivates Hec1/Nek2 through protein degradation, causing chromosome missegregation.
- Induces mitotic defects and apoptosis in cultured cells (~20% apoptotic cells at 72 h).
- Solid, white to off-white powder; soluble in DMSO (50 mg/mL) and in 10% DMSO/90% corn oil for animal dosing.
- Stable as powder at -20°C (3 years) and 4°C (2 years); in solvent stability varies by temperature.
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TARGETMOL CHEMICALS INC Daptomycin 100MG
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Also available in 1 mL, 10 mg, 25 mg, 50 mg, 200 mg and bulk. Please contact Fisher for quotes. Daptomycin (LY146032) is a cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA. Purity 99.61%
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eMolecules Medchem Express / IST5-002 / 1mg / 788478583 / HY-19527 / / 13484-66-7 / MFCD25541633 / 437.349 / C17H20N5O7P
Medchem Express / IST5-002 / 1mg / 788478583 / HY-19527 / / 13484-66-7 / MFCD25541633 / 437.349 / C17H20N5O7P
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Medchemexpress LLC RS 09 TFA | 99.9% | 805.80 | 5 MG
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RS 09 TFA is an LPS peptide mimic and TLR4 agonist that binds to TLR-4 and activates NF-κB. It functions as an adjuvant in vivo, enhancing antigen-specific immune responses.
- Stimulates TLR-4 and activates NF-κB in HEK-BLUETM-4 cells
- Binds to TLR-4 and induces nuclear translocation of NF-κB
- Induces secretion of inflammatory cytokines in RAW264.7 cells
- Increases nuclear NF-kB levels in RAW264.7 cells
- Enhances antigen-specific immune response as an adjuvant in BALB/c mice
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Medchemexpress LLC Fosmidomycin sodium salt | 66508-37-0 | 99.7% | 205.08 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Fosmidomycin sodium salt is a phosphonic acid antibiotic and an antimalarial agent. It is active against both Gram-negative and Gram-positive bacteria.
- Active against Gram-negative and Gram-positive bacteria.
- Demonstrated efficacy as an antimalarial agent in animal models and clinical trials.
- Effectively eliminates parasites in treated animals.
- Reduces parasitemias to less than 1% at specified dosages.
- Cures mice of malaria under specific treatment conditions.
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eMolecules Ambeed / 7-Methyl-7H-purin-6-amine / 100mg / 600851603 / A574718 / / 935-69-3 / MFCD00127790 / 149.157 / C6H7N5
Ambeed / 7-Methyl-7H-purin-6-amine / 100mg / 600851603 / A574718 / / 935-69-3 / MFCD00127790 / 149.157 / C6H7N5
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eMolecules Medchem Express / 3PO / 5mg / 446270433 / HY-19824 / / 18550-98-6 / MFCD00224002 / 210.236 / C13H10N2O
Medchem Express / 3PO / 5mg / 446270433 / HY-19824 / / 18550-98-6 / MFCD00224002 / 210.236 / C13H10N2O
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