Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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2,791 – 2,805 of 7,041 results

2,791

Research Products International Corp Cefsulodin, Sodium Salt, 100 Milligrams

Cefsulodin Sodium Salt is a cephalosporin antibiotic. Cefsulodin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This disruption interferes with the final stages of peptidoglycan synthesis in the bacterial cell wall, leading to structural instability and eventual cell lysis.

Effective against a range of Gram-negative bacteria, it is particularly useful in the isolation and selection of these bacteria in microbiological and research settings. Commonly used in culture media for the growth and identification of specific bacterial strains.

Additionally, it is often employed as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic. Its inclusion allows for the specific growth of Gram-negative bacteria lacking resistance to cefsulodin.

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2,792

Research Products International Corp Carbenicillin, Disodium Salt, 100 Gram

Carbenicillin, Disodium Salt is a semi-synthetic penicillin antibiotic effective against Gram-positive and Gram-negative bacteria. It is commonly used in molecular biology, genetic engineering, microbiology, and cell culture as a selective agent in plasmid-based cloning. It inhibits bacterial cell wall synthesis, allowing selection of cells expressing Carbenicillin resistance genes. This antibiotic prevents bacterial contamination in cell cultures and supports isolation and maintenance of resistant strains. Key features include broad-spectrum activity and stability in aqueous solutions.

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2,793

Research Products International Corp G-418 Disulfate, 25 Grams

G-418 Disulfate, also known as Geneticin, is an aminoglycoside antibiotic derived from Micromonospora rhodorangea. It is widely used in molecular biology and cell culture as a selective agent. G-418 inhibits protein synthesis by targeting the 80S ribosome, blocking translocation. It is commonly used to select genetically modified cells that carry a G-418 resistance gene, typically introduced via plasmid vectors. This allows for the isolation and maintenance of stable transfectants in gene expression, protein production, and cell line development studies. Its selectivity makes it a key tool in genetic engineering.

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2,794

Research Products International Corp Apramycin Sulfate [Nebramycin II], 25 Grams

Apramycin Sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the initiation complex formation and leading to misreading of the mRNA. This interference disrupts the translation process and inhibits bacterial growth.

Commonly used in microbiology to selectively isolate bacteria that are sensitive to this antibiotic. It is also used in antibiotic sensitivity testing to determine the susceptibility of bacterial strains. Its resistance genes are used as selectable markers in genetic engineering. Cells expressing the resistance gene can survive and proliferate in the presence of Apramycin, allowing for the selection of transfected or transduced cells.

Apramycin Sulfate is a valuable tool for selective bacterial isolation, antibiotic sensitivity testing, and selecting cells with specific genetic modifications in molecular biology experiments.

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2,795

Research Products International Corp Mitomycin C, 10 Milligrams

Mitomycin C is a potent antitumor antibiotic. It is derived from Streptomyces caespitosus and exhibits strong cytotoxic properties. It works by cross-linking DNA, inhibiting DNA synthesis, and inducing cell death. Mitomycin C finds applications in molecular biology and cell biology research. It is frequently employed as a DNA cross-linking agent in studies involving DNA damage and repair mechanisms.

Researchers use Mitomycin C to induce DNA adduct formation and study the cellular response to DNA damage. One notable feature of Mitomycin C is its ability to induce DNA cross-links in both dividing and non-dividing cells, making it useful for investigating cellular processes beyond actively dividing cells.

WARNING! This product can expose you to Mitomycin-C, a chemical which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

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2,796

Research Products International Corp Radicicol [Humicola Fuscoatra], 1 Milligram

Radicicol is a naturally occurring antibiotic and antifungal compound . It is known for its ability to inhibit the activity of heat shock protein 90 (Hsp90), a molecular chaperone that plays a crucial role in the folding and stabilization of various client proteins involved in cell signaling and regulation.

Radicicol is often used as a tool to study Hsp90-dependent processes and the functions of client proteins. Researchers use radicicol to investigate the impact of inhibiting Hsp90 on cellular pathways, protein folding, and cell viability. This compound is particularly valuable in cancer research, as many oncogenic proteins are dependent on Hsp90 for proper folding and stability.

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2,797

Research Products International Corp Penicillin G Potassium Salt, 100 Grams

Penicillin G potassium salt is a member of the penicillin class of antibiotics and is effective against a variety of gram-positive bacteria. As a narrow-spectrum antibiotic belonging to the beta-lactam class, it inhibits the synthesis of bacterial cell walls. It interferes with the formation of peptidoglycan, a crucial component of the bacterial cell wall. This weakens the cell wall and leads to the eventual rupture of the bacterial cell.

Penicillin G is effective against a wide range of Gram-positive bacteria, including Streptococcus, Staphylococcus, and some other species. However, it is not effective against Gram-negative bacteria due to their different cell wall structure.

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2,798

STEMCELL Technologies Bleomycin (Sulfate), Size: 5 mg

Bleomycin is a glycopeptide-derived antibiotic, isolated from the bacterium Streptomyces verticillus, that creates DNA strand scission and exhibits antitumor activity against squamous cell carcinomas and malignant lymphomas (Galm et al.). Bleomycin induces lung injury leading to acute inflammatory response and pulmonary fibrosis (Kulkarni et al.). This product is supplied as the sulfate salt of the molecule.CANCER RESEARCH· Induces single- and double-strand DNA breaks in tumor cells (Hecht).DISEASE MODELING· Induces lung fibrosis in mice (Kulkarni et al.).

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2,799

Research Products International Corp Timentin [Ticarcillin Disodium Salt/Potassium Cavulanate Mixture 15:1 Ratio], 25 Grams

Timentin contains two antibiotics: ticarcillin (a penicillin) and clavulanate potassium (a beta-lactamase inhibitor). The combination of ticarcillin and clavulanate enhances the spectrum of antibacterial activity by protecting ticarcillin from degradation by certain bacterial enzymes.

Ticarcillin inhibits bacterial cell wall synthesis, disrupting the integrity of the bacterial cell wall and leading to bacterial cell lysis. Clavulanate potassium works by inhibiting beta-lactamases, enzymes produced by bacteria that can inactivate beta-lactam antibiotics, such as ticarcillin. This combination is effective against a broad spectrum of bacteria, including those producing beta-lactamases.

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2,800

Chem-Impex International, Inc. Kanamycin monosulfate | 25389-94-0 | MFCD00070253 | 25G

Kanamycin monosulfate, 25389-94-0, MFCD00070253, 25G

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2,801

Ubpbio Carbenicillin disodium salt, CAS# 4800-94-6, > 95% purity

Carbenicillin is a semi-synthetic bactericidal antibiotic in the penicillin family. It primarily acts on Gram-negative bacteria. Carbenicillin is more stable than ampicillin and results in fewer satellite colonies on selection plates.

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2,802

Sigma Aldrich Fine Chemicals Biosciences Erythromycin potency 85025G

Chemical structure macrolide

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2,803

Research Products International Corp Methicillin Sodium Salt, 250 Milligrams

Methicillin Sodium Salt is a chemical compound that belongs to the class of beta-lactam antibiotics known as penicillin.

It is a modified form of penicillin that was developed to be resistant to the effects of the enzyme penicillinase, which is produced by certain bacteria. This resistance allows methicillin to be effective against bacteria that have developed resistance to traditional penicillin antibiotics.

This chemical is primarily used as a selective agent in laboratory experiments to isolate and study bacteria that are resistant to methicillin and other related antibiotics. It is commonly used in microbiology research, particularly in studies focused on antibiotic resistance mechanisms and bacterial genetics.

Researchers may utilize Methicillin Sodium Salt in various techniques such as bacterial culture, antibiotic susceptibility testing, and identification of antibiotic resistance genes.

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2,804

Research Products International Corp Nourseothricin Sulfate [NTC] [clonNAT] [Streptothricin Sulfate], 500 Milligrams

Nourseothricin Sulfate, also known as Streptothricin, is a natural, broad-spectrum antibiotic derived from Streptomyces species. It is used as a selective agent in molecular biology, genetics, microbiology, and cell culture. It inhibits protein synthesis in bacterial and eukaryotic cells, enabling selection of transformed cells that express the NAT resistance gene. These cells produce Nourseothricin acetyltransferase, which inactivates the antibiotic. Nourseothricin is commonly used in gene expression studies, plasmid maintenance, and to eliminate bacterial or fungal contaminants from cultures, ensuring purity and stability of resistant strains.

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2,805

Research Products International Corp NP-40 Lysis High Salt Buffer Solution, 250 Milliliters

1X buffer used for extracting proteins from cells.

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Antibiotics

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Research Products International Corp Cefsulodin, Sodium Salt, 100 Milligrams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Carbenicillin, Disodium Salt, 100 Gram Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp G-418 Disulfate, 25 Grams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Apramycin Sulfate [Nebramycin II], 25 Grams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Mitomycin C, 10 Milligrams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Radicicol [Humicola Fuscoatra], 1 Milligram Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Penicillin G Potassium Salt, 100 Grams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Timentin [Ticarcillin Disodium Salt/Potassium Cavulanate Mixture 15:1 Ratio], 25 Grams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Ubpbio Carbenicillin disodium salt, CAS# 4800-94-6, > 95% purity Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Methicillin Sodium Salt, 250 Milligrams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Nourseothricin Sulfate [NTC] [clonNAT] [Streptothricin Sulfate], 500 Milligrams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp NP-40 Lysis High Salt Buffer Solution, 250 Milliliters Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More