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Filtered Search Results
Medchemexpress LLC HS-276 | 2767422-72-8 | 98.9% | 419.52 | 100 MG
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HS-276 is an orally active, potent, and highly selective TAK1 inhibitor with a Ki of 2.5 nM. It significantly inhibits multiple kinases, including TAK1, CLK2, GCK, ULK2, and MAP4K5. This compound is useful for rheumatoid arthritis (RA) research due to its ability to reduce inflammation and improve arthritis markers in models.
- Orally active and highly selective TAK1 inhibitor
- Inhibits various kinases, such as TAK1, CLK2, and GCK
- Reduces expression of TNF, IL-6, and IL-1β
- Decreases inflammation and cartilage damage in inflammatory arthritis models
- Exhibits excellent bioavailability in in vivo studies
- Suitable for rheumatoid arthritis research
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Medchemexpress LLC Vancomycin (Standard) | 1404-90-6 | 95.9% | 100 MG
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Vancomycin (Standard) is an analytical standard and antibiotic used for treating bacterial infections. It is intended for research and analytical applications.
- Analytical standard for Vancomycin
- Used in qualitative, quantitative, and methodological research
- Suitable for applications such as HPLC, GC, and MS
- Treats bacterial infections
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Enzo Life Sciences Concanamycin A (25µg). CAS: 80890-47-7
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Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1 (BML-CM110). Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Exhibits cytotoxic effects in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Inhibits Autophagy. Alternative name: Folimycin. Purity: ≥98% (HPLC). Appearance: White to off-white solid (sub-milligram quantities will appear as clear film). Solubility: Soluble in methanol, DMSO or acetonitrile; insoluble in water. Long Term Storage: -20°C.
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eMolecules 3615-17-6 | N-Acetyl-D-mannosamine | MFCD09756160 | 1g
Medchem Express | Velusetrag | 5mg | 634371096 | HY-10457 | 866933-46-2 | 504.650 | C25H36N4O5S
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Medchemexpress LLC HY-124617A 5mg Medchemexpress, AMXT-1501 tetrahydrochloride CAS: Purity:>98%
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Medchemexpress, HY-124617A 5mg AMXT-1501 tetraHCl CAS: AMXT-1501 tetrahydrochloride is a polyamine transport inhibitor. AMXT1501 blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Rifampin(Synonyms: Rifampicin, Rifaldazine, Rifadin, Rimactane, Rifoldin, Rofact, Rifamycin AMP, Riforal), 10mM (in 1mL DMSO), CAS: 13292-46-1.
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Rifampin (CAS 13292-46-1) is an antibiotic belonging to the rifamycin family characterized by bactericidal activity via selective inhibition of bacterial DNA-dependent RNA polymerase This inhibition disrupts transcriptional initiation by preventing RNA synthesis leading to impaired bacterial protein biosynthesis and subsequent cell death In biomedical research rifampin serves as an essential tool for investigations into bacterial resistance mechanisms transcriptional regulation and synthetic biology studies that rely on specific transcription inhibition
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Medchemexpress LLC HY-105272 10mg Medchemexpress, Loreclezole CAS:117857-45-1 Purity:>98%
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Medchemexpress, HY-105272 10mg Loreclezole CAS:117857-45-1 Loreclezole, an antiepileptic compound, is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit containing receptors. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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AdipoGen Epoxomicin,Chemical. CAS: 134381-21-8
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Epoxomicin, AdipoGen Life Sciences. Chemical. CAS: 134381-21-8. Formula: C28H50N4O7. MW: 554.7. Synthetic. Antibiotic. Potent anticancer compound. Cell permeable, potent, selective and irreversible 20S proteasome inhibitor. Predominantly inhibits the chymotrypsin-like (CTRL) activity of the proteasome. Exhibits lower level inhibition of proteasome trypsin-like and caspase-like activitives (100 and 1,000-fold slower rates respectively). Anti-inflammatory. Antimicrobial and antimalarial. Anti-parasitic. Stimulates bone formation by inhibiting osteoblast proteasome activity. Induces Parkinson's-like symptoms in rats. The ubiquitin-proteasome system (UPS) and autophagy serve as two complementary, reciprocally regulated protein degradation systems. Blockade of UPS by Epoxomicin activates autophagy.
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eMolecules 858668-07-2 | Medchem Express | EMD534085 | 1mg | 446264867 | HY-15000 | MFCD22628820 | 476.544 | C25H31F3N4O2
Medchem Express | EMD534085 | 1mg | 446264867 | HY-15000 | 858668-07-2 | MFCD22628820 | 476.544 | C25H31F3N4O2
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Research Products International Corp Kanamycin A, 100 G
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Kanamycin A is a broad-spectrum aminoglycoside antibiotic derived from Streptomyces kanamyceticus. It is widely used in microbiology, molecular biology, and genetic engineering as a selective agent. Commonly added to culture media, Kanamycin A inhibits the growth of non-resistant bacteria, allowing selection of cells carrying a kanamycin resistance gene. It is frequently used in recombinant DNA experiments and as a selectable marker in plasmids and other vectors. Researchers also use it to study bacterial resistance and antimicrobial efficacy. Its potency and low toxicity make it valuable in protein expression and genetic studies.
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Medchemexpress LLC Chloramphenicol (Standard) | 56-75-7 | 99.7% | 25 MG
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Chloramphenicol is an analytical standard intended for research and analytical applications. It is an orally active, potent, and broad-spectrum antibiotic with antibacterial activity. It represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells, suppressing mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, leading to decreased VEGF release.
- Used as an analytical standard for research and analytical applications.
- Potent, orally active, broad-spectrum antibiotic.
- Exhibits antibacterial activity.
- Represses HIF-1α in hypoxic A549 and H1299 cells.
- Suppresses mRNA levels of VEGF and glucose transporter 1.
- Decreases VEGF release.
- Suitable for anaerobic infections and lung cancer research.
- Commonly used in HPLC, GC, and MS as a reference standard.
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Sigma Aldrich Fine Chemicals Biosciences Enrofloxacin United States Pharmacopeia (USP) Reference Standard | 93106-60-6 | MFCD00792463 | 200MG
Enrofloxacin United States Pharmacopeia (USP) Reference Standard | Mol Wt: 359.39 | 93106-60-6 | MFCD00792463 | 200MG
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Medchemexpress LLC Carbamic acid, N-[(1S)-1-[[(1-formyl-2-phenylethyl)amino]carbonyl]-2-methylpropyl]-, phenylmethyl | 88191-84-8 | 97.0% | 382.45 | 100 MG
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MDL-28170 (Calpain Inhibitor III) is a potent, selective, and membrane-permeable cysteine protease inhibitor of calpain that rapidly penetrates the blood-brain barrier following systemic administration. It also blocks γ-secretase.
- Potent, selective, and membrane-permeable cysteine protease inhibitor of calpain.
- Rapidly penetrates the blood-brain barrier following systemic administration.
- Blocks γ-secretase.
- Significantly and time-dependently improves the recovery of synaptic responses in hippocampal slices following prolonged, moderate hypoxia without hypoxic depolarization (In Vitro).
- Dose-dependently inhibits brain cysteine proteinase activity with an in vitro Ki of 0.01 μM.
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Medchemexpress LLC Saroglitazar magnesium | 1639792-20-3 | 98.0% | 901.42 | 1 MG
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Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity, having EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. It is for research use only.
- Pparα agonist (ec50: 0.65 pm in hepg2 cells)
- Moderate pparγ activity (ec50: 3 nm in hepg2 cells)
- Causes dose-dependent reductions in serum triglycerides, free fatty acids, and glucose in db/db mice.
- Shown efficacy in lowering triglycerides in wistar rats and marmosets.
- Appears to have good potential as a therapeutic agent for dyslipidemia and diabetes.
- Appearance: solid
- Color: off-white to light yellow
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Teknova 15mg/mL Tetracycline in 50% Ethanol Solution. 25mL, Sterile.
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Premade antibiotic solutions are ready-to-use as a supplement for your tissue culture, bacteria media or other specific needs. Antibiotics are often used in cell culture to prevent contamination, maintain aseptic conditions, or select for cells containing genetic modifications.
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