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Filtered Search Results
Research Products International Corp Chlortetracycline Hydrochloride, 100 Grams
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Chlortetracycline Hydrochloride is a tetracycline antibiotic. Chlortetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the attachment of aminoacyl-tRNA to the mRNA-ribosome complex. The interference disrupts the translation process and inhibits bacterial growth.
This antibiotic offers a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative bacteria. It also forms complexes with calcium, magnesium, aluminum, and iron, leading to reduced absorption.
Additionally, it is useful to study bacterial susceptibility patterns or as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic.
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Research Products International Corp D-Cycloserine, 1 Gram
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D-cycloserine is an antibiotic and structural analog of the amino acid D-alanine. It inhibits cell wall synthesis in certain bacteria, including Mycobacterium tuberculosis.
While it was initially identified as an antibiotic, D-cycloserine has gained attention for its activity as a partial agonist at the N-methyl-D-aspartate (NMDA) receptor, a type of glutamate receptor in the brain. Researchers study the mechanisms of neurotransmission and synaptic plasticity due to its interactions with NMDA receptors.
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Research Products International Corp Amoxicillin Trihydrate, 25 Grams
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Amoxicillin is a broad-spectrum, semi-synthetic penicillin antibiotic that is effective against a wide range of bacteria. The trihydrate form of amoxicillin is a crystalline powder that is often used in laboratory settings.
Amoxicillin inhibits the growth of bacteria by interfering with their cell wall synthesis. It is a versatile antibiotic with low toxicity to mammalian cells, making it a valuable tool in maintaining sterile conditions in cell cultures and studying bacterial physiology.
Researchers use amoxicillin to selectively culture bacteria or to treat bacterial infections in cell cultures.
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Research Products International Corp Ampicillin, Sodium Salt, 1 Gram
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Ampicillin, Sodium Salt is a semi-synthetic penicillin antibiotic effective against a broad range of Gram-positive and Gram-negative bacteria. Supplied as a powder, it is commonly used in molecular biology, microbiology, and genetic engineering. It serves as a selective agent in plasmid-based cloning and helps prevent bacterial contamination in cell cultures. By inhibiting bacterial cell wall synthesis, it ensures the purity of cultures and enables selection of Ampicillin-resistant strains. Key features include broad-spectrum activity, DNase/RNase-free quality, and good stability in aqueous solution, allowing for flexible handling.
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Research Products International Corp Amoxicillin Trihydrate, 50 Grams
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Amoxicillin is a broad-spectrum, semi-synthetic penicillin antibiotic that is effective against a wide range of bacteria. The trihydrate form of amoxicillin is a crystalline powder that is often used in laboratory settings.
Amoxicillin inhibits the growth of bacteria by interfering with their cell wall synthesis. It is a versatile antibiotic with low toxicity to mammalian cells, making it a valuable tool in maintaining sterile conditions in cell cultures and studying bacterial physiology.
Researchers use amoxicillin to selectively culture bacteria or to treat bacterial infections in cell cultures.
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![Research Products International Corp Apramycin Sulfate [Nebramycin II], 10 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-A50020-10.0.JPG-250.jpg)
Research Products International Corp Apramycin Sulfate [Nebramycin II], 10 Grams
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Apramycin Sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the initiation complex formation and leading to misreading of the mRNA. This interference disrupts the translation process and inhibits bacterial growth.
Commonly used in microbiology to selectively isolate bacteria that are sensitive to this antibiotic. It is also used in antibiotic sensitivity testing to determine the susceptibility of bacterial strains. Its resistance genes are used as selectable markers in genetic engineering. Cells expressing the resistance gene can survive and proliferate in the presence of Apramycin, allowing for the selection of transfected or transduced cells.
Apramycin Sulfate is a valuable tool for selective bacterial isolation, antibiotic sensitivity testing, and selecting cells with specific genetic modifications in molecular biology experiments.
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![Research Products International Corp Apramycin Sulfate [Nebramycin II], 1 Gram](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-A50020-1.02.JPG-250.jpg)
Research Products International Corp Apramycin Sulfate [Nebramycin II], 1 Gram
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Apramycin Sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the initiation complex formation and leading to misreading of the mRNA. This interference disrupts the translation process and inhibits bacterial growth.
Commonly used in microbiology to selectively isolate bacteria that are sensitive to this antibiotic. It is also used in antibiotic sensitivity testing to determine the susceptibility of bacterial strains. Its resistance genes are used as selectable markers in genetic engineering. Cells expressing the resistance gene can survive and proliferate in the presence of Apramycin, allowing for the selection of transfected or transduced cells.
Apramycin Sulfate is a valuable tool for selective bacterial isolation, antibiotic sensitivity testing, and selecting cells with specific genetic modifications in molecular biology experiments.
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Research Products International Corp Amphotericin B, 1 Gram
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Amphotericin B is a polyene antifungal agent known for its efficacy against a broad spectrum of fungi, including yeast and molds. It functions by binding to the fungal cell membrane, forming pores that disrupt membrane integrity. This disruption leads to the leakage of cellular contents, ultimately causing fungal cell death.
Amphotericin B is commonly used to prevent and treat fungal contamination in cell cultures and microbiological experiments. It is added to growth media to maintain aseptic conditions and protect cell lines from fungal overgrowth.
The antifungal activity of Amphotericin B makes it a valuable tool in maintaining the integrity of cell cultures and ensuring reliable experimental results.
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Research Products International Corp Amoxicillin Trihydrate, 10 Grams
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Amoxicillin is a broad-spectrum, semi-synthetic penicillin antibiotic that is effective against a wide range of bacteria. The trihydrate form of amoxicillin is a crystalline powder that is often used in laboratory settings.
Amoxicillin inhibits the growth of bacteria by interfering with their cell wall synthesis. It is a versatile antibiotic with low toxicity to mammalian cells, making it a valuable tool in maintaining sterile conditions in cell cultures and studying bacterial physiology.
Researchers use amoxicillin to selectively culture bacteria or to treat bacterial infections in cell cultures.
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Research Products International Corp Amphotericin B, 5 Grams
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Amphotericin B is a polyene antifungal agent known for its efficacy against a broad spectrum of fungi, including yeast and molds. It functions by binding to the fungal cell membrane, forming pores that disrupt membrane integrity. This disruption leads to the leakage of cellular contents, ultimately causing fungal cell death.
Amphotericin B is commonly used to prevent and treat fungal contamination in cell cultures and microbiological experiments. It is added to growth media to maintain aseptic conditions and protect cell lines from fungal overgrowth.
The antifungal activity of Amphotericin B makes it a valuable tool in maintaining the integrity of cell cultures and ensuring reliable experimental results.
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![Research Products International Corp Kanamycin Monosulfate [Kanamycin A], 5 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-K22000-5.0.JPG-250.jpg)
Research Products International Corp Kanamycin Monosulfate [Kanamycin A], 5 Grams
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Kanamycin A is a broad-spectrum aminoglycoside antibiotic derived from Streptomyces kanamyceticus. It is widely used in microbiology, molecular biology, and genetic engineering as a selective agent. Commonly added to culture media, Kanamycin A inhibits the growth of non-resistant bacteria, allowing selection of cells carrying a kanamycin resistance gene. It is frequently used in recombinant DNA experiments and as a selectable marker in plasmids and other vectors. Researchers also use it to study bacterial resistance and antimicrobial efficacy. Its potency and low toxicity make it valuable in protein expression and genetic studies.
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![Research Products International Corp Kanamycin Monosulfate [Kanamycin A], 10 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-K22000-10.0.JPG-250.jpg)
Research Products International Corp Kanamycin Monosulfate [Kanamycin A], 10 Grams
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Kanamycin A is a broad-spectrum aminoglycoside antibiotic derived from Streptomyces kanamyceticus. It is widely used in microbiology, molecular biology, and genetic engineering as a selective agent. Commonly added to culture media, Kanamycin A inhibits the growth of non-resistant bacteria, allowing selection of cells carrying a kanamycin resistance gene. It is frequently used in recombinant DNA experiments and as a selectable marker in plasmids and other vectors. Researchers also use it to study bacterial resistance and antimicrobial efficacy. Its potency and low toxicity make it valuable in protein expression and genetic studies.
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Medchemexpress LLC Hygromycin B | 31282-04-9 | >99.9% | 10 G
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Hygromycin B, also known as Hygrovetine, is an aminoglycoside antibiotic effective against both prokaryotic and eukaryotic cells. It functions by strongly inhibiting 70S and 80S ribosomes, thereby preventing protein synthesis through ribosomal translocation. Synthesized by *Streptomyces hygroscopicus*, it is widely used in research applications, including resistance selection in transgenic models.
- Active against prokaryotic and eukaryotic cells
- Inhibits protein synthesis by blocking 70S and 80S ribosomes
- Prevents ribosomal translocation
- Used in resistance selection experiments
- Applicable in cell proliferation/viability assays
- Suitable for Western blot and immunofluorescence analyses
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Medchemexpress LLC Isoniazid-d4 | 774596-24-6 | 99.9% | 5 MG
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Isoniazid-d4 is the deuterium-labeled Isoniazid. Isoniazid (INH) is a proagent that requires activation by the bacterial catalase-peroxidase enzyme KatG. It is bactericidal to rapidly dividing mycobacteria and exhibits anti-tuberculostatic activity.
- Can be utilized as a tracer
- Can serve as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS
- Deuteration has potential to influence pharmacokinetic and metabolic profiles of drugs
- Suitable for research use only
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Apexbio Technology LLC Geldanamycin 30562-34-6 10mM (in 1mL DMSO)
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Geldanamycin is an antibiotic from Streptomyces hygroscopicus that inhibits heat shock protein 90 (Hsp90) by binding to its ATP-binding pocket This disruption affects protein folding and stabilization impacting cell proliferation stress response and tumor biology Geldanamycin is used as a molecular tool in these studies and has activity against various microbes including bacteria fungi protozoa and nematodes IC50 values range from nanomolar to micromolar levels depending on the cell line and conditions It is also applied in research on vascular relaxation glucocorticoid receptor modulation and inflammation-related signaling pathways
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