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Filtered Search Results
MEDCHEMEXPRESS LLC TYLOSIN TARTRATE 50MG
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501874116 TYLOSIN TARTRATE 50MG
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MEDCHEMEXPRESS LLC NAFTIFINE HYDROCHLORIDE 1G
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501874115 NAFTIFINE HYDROCHLORIDE 1G
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Medchemexpress LLC Ciclopirox | 29342-05-0 | 98.3% | 50 MG
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Ciclopirox is a synthetic and orally active antifungal agent primarily used for superficial mycoses research. This broad-spectrum agent effectively inhibits dermatophytes, yeasts, molds, and various pathogenic Gram-positive and Gram-negative species. Beyond its antifungal properties, Ciclopirox also demonstrates anticancer and anti-inflammatory effects. It is intended for research use only.
- Synthetic and orally active antifungal agent
- Broad spectrum of activity against dermatophytes, yeasts, molds, and many pathogenic bacteria
- Exhibits anticancer and anti-inflammatory effects
- Inhibits HUVEC proliferation and angiogenesis
- Induces cell aerobic glycolysis
- Impairs mitochondrial functions and enhances ROS generation
- Activates PERK-dependent ER stress
- Reduces tumor size in mouse xenograft models
- Inhibits tumor growth in human breast cancer xenografts in mice
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Apexbio Technology LLC Glycopyrrolate 596-51-0 10mg
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Glycopyrrolate (CAS 596-51-0) is a small molecule that acts as a competitive antagonist of muscarinic acetylcholine receptors By blocking muscarinic receptor-mediated cholinergic signaling it inhibits smooth muscle contractions and reduces secretory gland activity This pharmacological profile makes glycopyrrolate a valuable tool in studies investigating muscarinic receptor function neurotransmission and cholinergic pathways It is frequently used in research focused on gastrointestinal motility airway regulation and autonomic nervous system modulation
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Apexbio Technology LLC Etifoxine hydrochloride 56776-32-0 10mg
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Etifoxine hydrochloride (CAS 56776-32-0) is a small molecule that modulates GABAA receptor activity with selectivity towards receptors containing 2 or 3 subunits In neuronal cell culture models it enhances GABAA receptor-mediated responses Etifoxine also binds to the translocator protein (TSPO) a mitochondrial protein involved in neurosteroidogenesis In preclinical and clinical studies etifoxine demonstrates anxiolytic effects without producing sedative muscle relaxant or cognitive impairment typically associated with benzodiazepines Additionally it has been reported to promote axonal regeneration supporting its utility in neuropharmacological and neuroregeneration research
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Medchemexpress LLC Actinomycin X2 (Actinomycin V) | 18865-48-0 | MFCD00076115 | 98.0% | 1269.40 | C62H84N12O17 | 1MG
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Actinomycin X2 is a cyclic peptide antibiotic used in research for antibacterial and anticancer studies, including apoptosis induction and mechanistic pathway analysis. It is supplied as an orange-red solid powder suitable for biochemical and cell-based assays.
- Cyclic peptide antibiotic with antibacterial and anticancer activity.
- Used in research for apoptosis induction and pathway analysis.
- Appearance: orange to red solid powder.
- Purity: 98.0%.
- Molecular weight: 1269.40 g/mol; formula C62H84N12O17.
- CAS number 18865-48-0.
- Storage: powder -80°C (2 years) or -20°C (1 year); in solvent -80°C (6 months) or -20°C (1 month).
- Pack size: 1 mg vial; additional sizes available by request.
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Apexbio Technology LLC Azithromycin Dihydrate 117772-70-0 25mg
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Azithromycin Dihydrate (CAS 117772-70-0) is a macrolide antibiotic targeting the bacterial 50S ribosomal subunit It is designed to inhibit bacterial protein synthesis thereby disrupting bacterial growth and replication Azithromycin Dihydrate exerts its biological activity primarily through reversible binding to the 50S ribosomal subunit inhibiting protein synthesis In in vitro assays Azithromycin Dihydrate demonstrates inhibitory activity against susceptible bacterial strains with reported IC50 values typically in the micromolar range Based on these pharmacological properties Azithromycin Dihydrate holds research potential in investigating mechanisms of antibiotic resistance bacterial susceptibility and developing therapeutic strategies against bacterial infections
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Apexbio Technology LLC SJB2-043 63388-44-3 5mg
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SJB2-043 (CAS 63388-44-3) is a small molecule inhibitor of ubiquitin-specific protease 1 (USP1) a deubiquitinating enzyme involved in the regulation of DNA repair by deubiquitinating key proteins in the Fanconi anemia (FA) pathway SJB2-043 exhibits an IC50 of 0 544 M for USP1 In cellular models such as K562 leukemia cells and primary AML cells SJB2-043 reduces USP1 levels and promotes proteasomal degradation of ID1 as well as decreasing ID2 and ID3 protein levels Treatment with SJB2-043 also increases Ub-FANCD2 and Ub-PCNA in HeLa cells reflecting modulation of DNA repair processes This compound serves as a valuable tool for studies investigating USP1 function and the regulation of ID proteins in cancer and stem cell biology
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Apexbio Technology LLC CORM-3 475473-26-8 20mg
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CORM-3 (CAS 475473-26-8) is a water-soluble carbon monoxide-releasing molecule used in biomedical research It delivers controlled CO release activating soluble guanylate cyclase to mimic the anti-inflammatory effects observed with heme oxygenase activity In vitro studies have demonstrated that CORM-3 reduces PMN-induced CD54 expression on endothelial cells and exhibits vasoactive properties including modulation of vascular tone and blood pressure Additionally CORM-3 displays broad-spectrum antimicrobial activity by increasing membrane permeability and inhibiting terminal oxidases in pathogens This compound serves as a valuable tool for investigating CO s roles in cardiovascular inflammation vascular modulation and antimicrobial mechanisms
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Medchemexpress LLC Vancomycin | 1404-90-6 | 95.92% | 25 MG
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Vancomycin is an analytical standard and an antibiotic used for treating bacterial infections. It is intended for research and analytical applications.
- It serves as a reference standard for assays.
- It is commonly utilized in qualitative, quantitative, and methodological research experiments, including HPLC, GC, and MS.
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Apexbio Technology LLC Merimepodib 198821-22-6 2mg
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Merimepodib (CAS 198821-22-6) is a small-molecule inhibitor targeting inosine monophosphate dehydrogenase (IMPDH) It is designed to inhibit IMPDH thereby blocking the conversion of inosine monophosphate to xanthosine monophosphate and impacting guanine nucleotide biosynthesis Merimepodib exerts its biological activity primarily through noncompetitive inhibition of IMPDH In in vitro studies Merimepodib demonstrates antiproliferative effects suppressing lymphocyte cell growth at approximately 100 nM It also shows antiviral activity with IC50 values of 0 38 M for HBV 0 80 M for HCMV 1 0 M for EMCV and 1 14 M for RSV Based on these pharmacological properties Merimepodib holds research potential in antiviral therapy immunosuppression and transplant rejection models
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000739124 CLARITHROMYCIN IMPUR 5MG
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MEDCHEMEXPRESS LLC TCS JNK 5A 10MG
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501873382 TCS JNK 5A 10MG
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MEDCHEMEXPRESS LLC GRISEOFULVIN 5G
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501873606 GRISEOFULVIN 5G
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Medchemexpress LLC HY-N0644 10mg Medchemexpress, Carnosic acid CAS:3650-09-7 Purity:>98%
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Medchemexpress, HY-N0644 10mg Carnosic acid CAS:3650-09-7 Carnosic acid has demonstrated inhibition of oxidative stress and inflammation, suppression of cell proliferation, and antibacterial activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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