FGF basic/bFGF Protein, Human (146a.a) is a 146 amino acid protein produced by E.coli with tag-free purification. It plays a key role in bone healing, cartilage repair, bone repair, and nerve regeneration. This protein acts as a mitotic promoter, accelerating cell proliferation, and regulates immune processes by activating the FGF/FGFR signaling pathway, including the JAK-STAT and ERK pathways, to promote cartilage regeneration.
- Supports tissue repair processes such as bone healing and nerve regeneration.
- Promotes cell proliferation, differentiation, and apoptosis.
- Activates FGF/FR signaling pathways to regulate cartilage metabolism.
- Exhibits high biological activity with an ED50 of <2 ng/mL.
- Implicated in cancer research, particularly in glioblastoma multiforme (GBM).
- Produced in E. coli with tag-free purification.