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MW 225.22 Da. Selective GABAB antagonist (IC50 = 34 μM). Brain penetrant *in vivo*. Also available in simple stock solutions (ab146707) - add 1 ml of water to get an exact, ready-to-use concentration.
MW 225.22 Da. Selective GABAB antagonist (IC50 = 34 μM). Brain penetrant *in vivo*. Also available in simple stock solutions (ab146707) - add 1 ml of water to get an exact, ready-to-use concentration.
Recombinant CHO-K1 cells stably overexpress human adenosine A2B receptor (ADORA2B) on the surface and contain high levels of G protein G s to couple with the receptor in downstream signaling pathways
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Recombinant CHO-K1 cells stably overexpress human opioid receptor kappa 1 (OPRK1) on the surface and contain high levels of G protein G i to couple with the receptor in downstream signaling pathways
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Recombinant CHO-K1 cells stably overexpress human adrenoceptor alpha 2A (ADRA2A) on the surface and contain high levels of G protein G i to couple with the receptor in downstream signaling pathways
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GPR103 is known as an orphan G protein-coupled receptor with reported expression in brain heart kidney adrenal gland retina and testis GPR103 mRNA has been reported to be highly expressed in the superficial layers of the entire spinal cord and a high density of 26RFa binding sites was observed in the superficial layers of the dorsal horn QRFP binds and activates the human GPR103 as well as mouse GPR103A and GPR103B with nanomolar affinities in transfected cells Therefore the current experiments investigated the effects of QRFP administration in rats and the effects of a high fat diet on prepro-QRFP mRNA and GPR103 receptor mRNA levels 26RFa and QRFP are endogenous ligands of GPR103 An immunohistochemical study revealed that GPR103-like immunoreactivity (LI) was observed in the superficial layers of spinal dorsal horn that QRFP-LI was observed in the dorsal root ganglion and that intrathecal 26RFa suppressed the expression of Fos-LI induced by paw formalin injection in
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Primary bone marrow mononuclear cells (a.k.a. BM MNCs or BMNCs) are a heterogeneous population that includes hematopoietic lineage cells such as lymphocytes, monocytes, stem cells, and progenitor cells as well as mesenchymal stromal cells. Mononuclear cells are isolated from human adult bone marrow using density gradient separation. Heparin is added to the bone marrow upon collection as an anticoagulant.Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More