General Cell Lines and Cell Cultures
Genscript Corporation HEK293/GCGR/G15 Stable Cell L
Recombinant HEK293 cells stably overexpress human glucagon receptor (GCGR) on the surface and contain high levels of G protein G s to couple with the receptor in downstream signaling pathways
ATCC Fannyhessea vaginae
Fannyhessea vaginae strain CCUG 38953 is a whole-genome sequenced bacterial type strain that was isolated in Goteborg, Sweden, from the vaginal flora of a healthy woman. This strain has been sequenced as a reference genome for the NIH Human Microbiome Project.
Promocell GmbH PromoCell SkMC Pellet from > 1 million Normal Human Skeletal Muscle Cells
Cell pellet consisting of 1 million cells dissolved in 200µl RNAlater for subsequent RNA, DNA or protein analysis. Note: Cell pellets cannot be revived.Our Cell Pellets are stored in RNAlater – an aqueous protection solution that rapidly permeates the cells and stabilizes cellular DNA, RNA, and proteins and protects them from degradation. This makes our Cell Pellets very useful for a wide range of research applications like gene expression analysis, cell characterization studies, and protein characterization experiments.Each Cell Pellet is made from 1 million cells and is dissolved in 200 µl RNAlater. The Cell Pellets are produced from released cell lots and have the same characteristics, i.e. expression profile or cell type specific antigens. On request, viable cells from the same lot are available for cultivation.
Eurofins Discoverx PathHunter CCR10 Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0783C3)
The PathHunter CCR10 Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of CCR10 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CCR10. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CCR10-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen EP4 Prostanoid Receptor Stable Cell Line, 2 vials. (HTS142C)
The ChemiScreen EP4 Prostanoid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin E2) based activation of PTGER4 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGER4 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of PTGER4, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Biochain Institute Inc Frozen Tissue Section - Alzheimer's Disease: Brain: Pons, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx PathHunter U2OS NIK Signaling Assay, 2 vials. (93-1059C3)
The PathHunter NIK Checkpoint Signaling cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting signaling checkpoints. This cell line enables assessment of ligand (e.g. CD40, TWEAK) induced non-canonical NF-κB signaling via detection of NIK stabilization. This product uses EFC technology. The included cell line overexpresses ED-tagged NIK (NF-kappa-B Inducing Kinase) protein. Upon activation of NFκB signaling by a ligand or an antibody, NIK is stabilized, allowing detection of EFC signal when treated with exogenous EA. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/checkpoint.
Eurofins Discoverx PathHunter CHO-K1 MTNR1B β-Arrestin Cell Line, 2 vials. (93-0630C2)
The PathHunter MTNR1B cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. melatonin) based activation of MTNR1B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MTNR1B and EA-tagged β-Arrestin-2. Activation of MTNR1B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC RK13 Kidney Rabbit (Oryctolagus cuniculus)
RK13 is a cell line exhibiting epithelial morphology that was isolated from the kidney of a rabbit. This cell line was deposited by BC Meyer.
ATCC SUP-B15; Lymphoblastic Leukemia; Human (Homo sapiens)
SUP-B15 is a B lymphoblast cell line that was isolated from the marrow of a White, 8-year-old, male patient with acute lymphoblastic leukemia (ALL). This cell line was deposited by SD Smith. It can be used in immunology and immune system disorder research.
Amsbio LLC ISRE Leeporter™ Luciferase Reporter-HEK293 Cell Line
ISRE Leeporter™ Luciferase Reporter-HEK293 Cell Line
