General Cell Lines and Cell Cultures
ATCC HCT116-SLC15A4-KO-c10; Colorectal carcinoma; Human (Homo sapiens)
The HCT116-SLC15A4-KO-c10 cell line contains a -7 deletion in SLC15A4 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.
Mycoplasma genitalium strain G37 (ATCC 33530™)
Mycoplasma genitalium strain G37 (ATCC 33530™) is a whole-genome sequenced type strain isolated from the urethra of a male patient with non-gonococcal urethritis. This bacterial culture has applications in infectious disease and sexually transmitted disease research. This culture produces a surface attachment protein.
Abcam Global Protein Synthesis Assay Kit.
Global Protein Synthesis Assay Kit.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter HEK 293 GPR173 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0380C1A)
The PathHunter GPR173 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR173 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR173 and EA-tagged β-Arrestin-2. Activation of GPR173 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx cAMP Hunter CHO-K1 HTR1A Gi Cell Line, 2 vials. (95-0132C2)
The cAMP Hunter HTR1A Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin/5-HT) based activation of HTR1A GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type HTR1A, a naturally Gi/Go coupled GPCR. Upon activation of HTR1A, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Enterococcus faecium
Enterococcus faecium is a multidrug-resistant, whole-genome sequenced bacterium that was isolated from human feces. This strain is confirmed by PCR to carry the vanA vancomycin resistance gene. It has applications in antimicrobial resistance research and drug development.
Eurofins Discoverx ChemiScreen PAR2 Receptor Membrane Preparation, 1 vial. (HTS037M)
The ChemiScreen PAR2 Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of F2RL1 surface expression. ChemiScreen membrane preps can be used to screen for GPCR activity using GTPγS assays. Increased GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Biochain Institute Inc Frozen Tissue Section - Depression: Brain: Frontal Lobe, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biochain Institute Inc Paraffin Tissue Section - Multiple Sclerosis Disease: Brain: Pons, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Promocell GmbH PromoCell HCAEC-c 500,000 Human Coronary Artery Endothelial Cells, cryopreserved
Primary Human Coronary Artery Endothelial Cells (HCAEC) are isolated from the coronary arteries (the right and the left coronary artery, including the anterior descending and the circumflex branches) from a single donor. They are crucially involved in the regulation of coronary blood flow and cardiac functions and are consequently useful for in vitro studies of diseases such as thrombosis, atherosclerosis, and hypertension. HCAEC are also suitable for studying functional vaso-dilators, such as prostacyclin, bradykinin, or nitric oxide.
iQ Biosciences SD Rat Bone Marrow Cells, 20M cells/vial
High-quality, high-viability (typically > 70%) bone marrow cells from the Sprague Dawley, rat a commonly-used outbred rat strain. Used for a wide variety of immunology-based applications, including cell population characterization and differentiation into specific cell types. All orders come with an iQ Certificate of Analysis.
Cayman Chemical OrexIn A amIdebovInhumn 500ug
A 33 amino acid hypothalamic neuropeptide with a role in appetite regulation, wakefulness, locomotor activity, sympathetic and HPA activity, and pain thresholds; binds the orexin-1 and -2 receptors with equal affinity
Eurofins Discoverx PathHunter CHO-K1 P2RY6 β-Arrestin Cell Line, 2 vials. (93-0500C2)
The PathHunter P2RY6 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. UTP) based activation of P2RY6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY6 and EA-tagged β-Arrestin-2. Activation of P2RY6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.