General Cell Lines and Cell Cultures
Eurofins Discoverx Ready-to-Assay MRGPRD Receptor Frozen Cells, 2 Vials of Cells. (HTS206RTA)
The Ready-to-Assay MRGPRD Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. β-alanine) based activation of MRGPRD GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MRGPRD alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of MRGPRD, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Cayman Chemical Acylated Ghrelin human Expre
This EIA kit specifically measures the acylated form of ghrelin.
Eurofins Discoverx PathHunter CHO-K1 BAI2 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0546C2)
The PathHunter BAI2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of BAI2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged BAI2 and EA-tagged β-Arrestin-2. Activation of BAI2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Amsbio LLC Flp recombinase Expression HEK293 stable cell
Flp recombinase Expression HEK293 stable cell
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Spleen, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Quantitative Genomic; DNA from Human; adenovirus 5; Strain: Adenoid 75
Quantitative genomic DNA from Human adenovirus 5 strain Adenoid 75 can be used for assay development, verification, and validation as well as monitoring of day to day test variation and lot to lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load.
Eurofins Discoverx Ready-to-Assay VPAC1 Receptor Frozen Cells, 2 Vials of Cells. (HTS043RTA)
The Ready-to-Assay VPAC1 Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. VIP) based activation of VIPR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses VIPR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of VIPR1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Yersinia; enterocolitica; subsp. enterocolitica
Yersinia enterocolitica subsp. enterocolitica strain 33114 was isolated in New York from a human tissue sample taken from a glanders-like infection on the face. The whole-genome sequenced bacterial type strain can be used in media testing and is recommended as a test microorganism for EP 2.6.27 Microbiological Control of Cellular Products.
Biochain Institute Inc Frozen Tissue Section - Arteriosclerosis: Aorta, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
ATCC HCT116-SLC25A46-KO-c12; Colorectal carcinoma; Human (Homo sapiens)
The HCT116-SLC25A46-KO-c12 cell line contains a -10 deletion/+10 insertion in SLC25A46 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.This cell line was generated by the RESOLUTE project.
Biochain Institute Inc Frozen Tissue Section - Human Diabetic Diseased Tissue: Heart, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biochain Institute Inc Frozen Tissue Section - Human Tumor: Prostate, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx InCELL Hunter HEK 293 BRD2(1) Bromodomain Cell Line, 2 vials. (96-0004C1)
The InCELL Hunter HEK 293 BRD2(1) Bromodomain Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with regulators of epigenetics pathways. This cell line enables assessment of compound-engagement-based stabilization of BRD2(1) via detection of BRD2(1) levels. This product uses EFC technology. The cell line included overexpresses BRD2(1) target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/epigenetics.
ATCC Mycobacterium tuberculosis; genomic DNA
Genomic DNA isolated from Mycobacterium tuberculosis TMC 303. This bacterial strain is also available as ATCC Catalog No. 35822™.
ATCC Trypanosoma cruzi; Y
Trypanosoma cruzi strain Y is a parasitic protozoan that was isolated from a Chagas' disease patient in Brazil. This strain has applications in vector-borne disease research.