General Cell Lines and Cell Cultures
ATCC Fusarium keratoplasticum; genomic DNA
Genomic DNA isolated from Fusarium keratoplasticum FIV/74. This fungal strain is also available as ATCC Catalog No.: 36031™.
ATCC Paraclostridium bifermentans; Strain 76
Paraclostridium bifermentans strain 76 is a bacterial anaerobe that is propagated at 37°C.
ATCC Salmonella enterica; subsp. enterica; serovar Abony
Salmonella enterica subsp. enterica serovar Abony strain CCM 4518 [NBRC 100797, NCTC 6017, CIP 80.39] is a whole-genome sequenced strain with applications in enteric disease research and zoonotic disease research.
ATCC Chlamydia trachomatis; Serovar D; Strain: UW-3/Cx
Chlamydia trachomatis serovar D strain UW-3/Cx is propagated in McCoy [McCoy B] cells (ATCC CRL-1696). This strain was isolated from the cervix of an asymptomatic human patient. This product has applications in infectious disease and sexually transmitted disease research.
Eurofins Discoverx cAMP Hunter CHO-K1 GPR84 Gi Cell Line, 2 vials. (95-0158C2)
The cAMP Hunter GPR84 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. embelin) based activation of GPR84 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GPR84, a naturally Gi/Go coupled GPCR. Upon activation of GPR84, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PrecisION hKir2.1 Recombinant Stable Cell Line, 2 vials. (CYL3032)
The PrecisION hKir2.1 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kir2.1 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kir2.1 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Eurofins Discoverx PrecisION hKv2.1 Recombinant Stable Cell Line, 2 vials. (CYL3022)
The PrecisION hKv2.1 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kv2.1 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kv2.1 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Eurofins Discoverx cAMP Hunter CHO-K1 AVPR2 Gs Cell Line, 2 vials. (95-0150C2)
The cAMP Hunter AVPR2 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. vasopressin) based activation of AVPR2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type AVPR2, a naturally Gs coupled GPCR. Upon activation of AVPR2, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx KILR Jurkat LAG3 Cell Line, 2 vials. (97-1038C019)
The KILR Jurkat LAG3 cell line is a stable, engineered target cell line to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint inhibitors, checkpoint agonists, bispecifics, CAR-T, and more) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell line overexpresses a ProLabel- tagged housekeeping gene as well as untagged LAG3. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell line. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
ATCC Salmonella enterica; subsp. enterica; serovar Braenderup
The DNA from this strain is used by laboratories in the Pulsenet system as the molecular size standard for pulsed-field gel electrophoresis (PFGE) analysis of bacterial pathogens (see notes).
Eurofins Discoverx PrecisION hNav1.7 Recombinant Stable Cell Line, 2 vials. (CYL3011)
The PrecisION hNav1.7 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Nav1.7 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Nav1.7 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Eurofins Discoverx PrecisION hNav1.4 Recombinant Stable Cell Line, 2 vials. (CYL3024)
The PrecisION hNav1.4 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Nav1.4 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Nav1.4 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
ATCC Rhizopus stolonifer; UNB-1
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Microsporum canis; Vasquez
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.