General Cell Lines and Cell Cultures
Cell Applications Inc Proliferating Lung Fibroblasts (HLF), Fetal
Proliferating Lung Fibroblasts (HLF), Fetal
Cell Applications Inc Proliferating Lung Fibroblasts (HLF), Fetal
Proliferating Lung Fibroblasts (HLF), Fetal
Amsbio LLC Human Normal Liver FFPE Tissue Block
Human FFPE tissue blocks are processed from diseased tissues or clinically-unremarkable donor normal human tissue samples. Tissue is prepared by a certified medical pathologist, fixed in 10% neutral formalin for 24 hours and embedded in IHC-grade paraffin. The target FFPE specimen size is 0.5 x 0.5 x 0.5 cm, but it can vary significantly depending on the organ.
Amsbio LLC Human Kidney (renal cell) normal FFPE tissue block
Human Kidney (renal cell) normal FFPE tissue block
Biochain Institute Inc Paraffin Tissue Section - Human Brain Tumor: Oligodendroglioma and Astrocytoma, Mixed Glioma, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Biochain Institute Inc Matched Pair - cDNA - Human Primary and Matched Metastatic Tumor Tissue: Breast, 10 x2 rxn /PK
BioChain's human cDNA matched pair products include: Primary Pair (PP), Primary and Metastasis Pair (PM). PP consists of cDNA prepared from primary tumor and its adjacent normal tissue; PM consists of cDNA prepared from primary tumor and corresponding metastatic tumor. cDNAs in each pair are prepared from the same donor. This product line is designed for identifying tumor-specific (or disease specific) genes and tumor metastatic genes.
ATCC Saccharomyces cerevisiae
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
Eurofins Discoverx cAMP Hunter CHO-K1 ADCYAP1R1 (PAC1) Gs Cell Line, 2 vials. (95-0064C2)
The cAMP Hunter ADCYAP1R1 (PAC1) Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PACAP) based activation of ADCYAP1R1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type ADCYAP1R1, a naturally Gs coupled GPCR. Upon activation of ADCYAP1R1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Genscript Corporation CHO-K1/G15/CXCR1
Chemokine (C-X-C motif) receptor 1 (CXCR1) is a rhodopsin-like G protein-coupled receptor It is one of two high-affinity receptors for the CXC chemokine interleukin-8 (IL-8) a major mediator of immune and inflammatory responses The structure of human CXCR1 in a lipid bilayer should help to facilitate the discovery of new compounds that interact with GPCRs GenScript s human CXCR1-expressing stable subline is guaranteed to function properly in the calcium flux assay
Eurofins Discoverx Ready-to-Assay LH Glycoprotein Hormone Receptor Frozen Cells, 2 Vials of Cells. (HTS233LRTA)
The Ready-to-Assay LH Glycoprotein Hormone Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. luteinizing hormone, hCG) based activation of LHCGR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses LHCGR alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of LHCGR, the resulting calcium activity can be assayed in either detection mode. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx PathHunter U2OS EphB2 Functional Assay, 2 vials. (93-0848C3)
The PathHunter U2OS EphB2 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphB2 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphB2 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC HT 1197; Urinary Bladder Carcinoma; Human (Homo sapiens)
HT-1197 is a cell isolated from the urinary bladder of a White, 44-year-old, male with carcinoma. This cell line was deposited by S Rasheed and can be used for immuno-oncology research.