General Cell Lines and Cell Cultures
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Blood Vessel: Vein, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx PathHunter HEK 293 IL11R/IL6ST Dimerization Cell Line, 2 vials. (93-1028C1)
The PathHunter IL11R/IL6ST Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. IL-11) induced dimerization of IL11R/IL6ST receptors. This product uses EFC technology. The cell line included overexpresses IL6ST target protein fused to PK alongside IL11R target protein fused to EA. Upon ligand-induced dimerization of IL11R/IL6ST, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/interleukins.
ATCC Dermal Fibroblasts; Normal, Human, Neonatal
Primary Dermal Fibroblast Normal; Human, Neonatal (HDFn) is a cell line isolated from neonatal foreskin that has research applications in responding to pathogens, skin aging, wound healing, gene delivery, and skin diseases, including scleroderma.
Eurofins Discoverx ChemiScreen Motilin Receptor Stable Cell Line, 2 vials. (HTS121C)
The ChemiScreen Motilin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. motilin) based activation of MLNR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MLNR alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of MLNR, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC SW480; Colon Adenocarcinoma; Human (Homo sapiens)
SW480 [SW-480] cells isolated from the large intestine of a Dukes C colorectal cancer patient and can be used in cancer research.
Neuvitro Collagen coated sterile German glass coverslips for cell culture, 12mm dia #1 thick 90/pk, ready to use in cell culture.
CE certified German glass coverslips with rat tail collagen I coating on both sides for cell culture and confocal / IHC imaging with no autofluorescence. Pre-washed, nitric acid treated, coated with pathgen-free rat tail collagen I and sterile. 12mm diameter round, #1 thickness, 90 pieces/pack. Ready to use directly in cell culture. Coverslips are sealed as 15 pieces per group for easy storage and enhanced cell culture quality. Shelf life 0.5 year when stored in chest freezer. User manual included.
Cellular Dynamics International iCell DopaNeurons PD GBA N370S Kit, 5.0 x 10^6 viable cells, cryopreserved kit, >80% TH-positive neurons, fully differentiated neurons, includes media supplements
The iCell DopaNeurons PD GBA N370S Kit from FUJIFILM CELLULAR DYNAMICS INC provides cryopreserved, human iPSC-derived midbrain dopaminergic neurons specifically designed for Parkinson's disease research. These cells are tailored to model the GBA N370S mutation, offering a biologically relevant in vitro system ideal for therapeutic discovery and drug screening. They are derived from participants in the Michael J. Fox Foundation's PPMI study, ensuring their physiological relevance through comprehensive clinical and biological data.
- Cell type: Human iPSC-derived midbrain dopaminergic neurons
- Disease model: Parkinson's disease
- Genetic mutation: GBA (N370S)
- Purity: >80% tyrosine hydroxylase (TH)-positive
- Fully differentiated neurons
- Quantity: >= 5.0 x 10^6 viable cells
- Optimal media included for various assays
- Functional recovery within 14 days of plating
- Shipping condition: Cryopreserved cells
Sciencell Research Laboratories Human Choroid Plexus Epithelial Cells, Cryopreserved, >5 x 10^5 cells, 1 ml
Human Choroid Plexus Epithelial Cells, Cryopreserved, >5 x 10^5 cells, 1 ml
Eurofins Discoverx PathHunter CHO-K1 GPR109B β-Arrestin Cell Line, 2 vials. (93-0791C2)
The PathHunter GPR109B cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. 3-hydroxyoctanoic acid) based activation of GPR109B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR109B and EA-tagged β-Arrestin-2. Activation of GPR109B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CRHR2 Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0752C3)
The PathHunter CRHR2 Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of CRHR2 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CRHR2. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CRHR2-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Amsbio LLC Human ACE2 (GFP) Expression in Hela Cell Line
Human ACE2 (GFP) Expression in Hela Cell Line
ATCC SK-BR-3; Breast Adenocarcinoma; Human (Homo sapiens)
SK-BR-3 [SKBR3] cells were isolated in 1970 from pleural effusion cells of a 43-year-old, White, female adenocarcinoma patient with blood type A+ who had been treated with radiation, steroids, cytoxan, and 5-fluorouracil. Use these cells in your breast cancer research.