General Cell Lines and Cell Cultures
ATCC Photobacterium leiognathi
Photobacterium leiognathi strain E28 is a strongly bioluminescent bacterium that was isolated from the Red Sea.
ATCC Staphylococcus; capitis; subsp. capitis
Staphylococcus capitis subsp. capitis strain LK 499 is a whole-genome sequenced bacterial type strain that was isolated from human skin.
Eurofins Discoverx KILR SK-MEL-28 Cell Pool, 2 vials. (97-1017P031)
The KILR SK-MEL-28 cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of SK-MEL-28 cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
ATCC Campylobacter rectus; Strain FDC 371; genomic DNA
Genomic DNA isolated from Campylobacter rectus Strain FDC 371. This bacterial strain is also available as ATCC Catalog No. 33238™.
Charles River Labs Cell Solutions PB CD3 CELLS- POS SEL CRYO 10M
For Research Use Only. Human Normal Peripheral Blood CD3+ Pan T Cells - Cryopreserved, 10 million cells/vial. Isolated using POSITIVE immunomagnetic cell separation procedures.
Creative Bioarray CAL-120 cells, human breast adenocarcinoma, pleural effusion derived, triple-negative, heterogeneous, adherent cells, monolayer culture, 90% DMEM + 10% h.i. FBS
CAL-120 cells, human breast adenocarcinoma, pleural effusion derived, triple-negative, heterogeneous, adherent cells, monolayer culture, 90% DMEM + 10% h.i. FBS
Eurofins Discoverx ChemiScreen M4 Muscarinic Acetylcholine Receptor Stable Cell Line, 2 vials. (HTS117C)
The ChemiScreen M4 Muscarinic Acetylcholine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. acetylcholine) based activation of CHRM4 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CHRM4 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CHRM4, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx FFAR1 (GPR40) Gq Calcium Signaling Cell-Based Assay Kit (CHO-K1)
The FFAR1 (GPR40) Gq Stable Cell Line Calcium Signaling Assay (CHO-K1) contains a stable clonal cell line used to measure FFAR1 (GPR40) (GPCR) activation via an increase in intracellular calcium. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Genscript Corporation CHO-K1/EDNRA Stable Cell Line
In mammals the endothelin (ET) family comprises three endogenous isoforms ET-1 ET-2 and ET-3 These endothelium-derived peptides perform their functions via two endothelin receptors classified as EDNRA and EDNRB EDNRA receptors are mainly localized in the vascular smooth muscle cells where they are the predominant sub-type and mediate vasoconstriction and proliferation Selective EDNRA antagonists are effective in the treatment of heart failure essential hypertension pulmonary hypertension and atherosclerosis
ATCC Aspergillus niger; WB 326
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
Genscript Corporation CHO-K1/M4/G15 Stable Cell Lin
Recombinant CHO-K1 cells stably overexpress human cholinergic receptor muscarinic 4 (M4) on the surface and contain high levels of G protein G i to couple with the receptor in downstream signaling pathways
ABclonal Technology ADRA1A Rabbit pAb
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
Eurofins Discoverx PathHunter HEK 293 GPR173 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0380C1A)
The PathHunter GPR173 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR173 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR173 and EA-tagged β-Arrestin-2. Activation of GPR173 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 mCCR4 β-Arrestin Cell Line, 2 vials. (93-0515C2)
The PathHunter mCCR4 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CCL22/MDC) based activation of mCCR4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCCR4 and EA-tagged β-Arrestin-2. Activation of mCCR4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.