General Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter CHO-K1 P2RY12 β-Arrestin Cell Line, 2 vials. (93-0262C2)
The PathHunter P2RY12 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ATP) based activation of P2RY12 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY12 and EA-tagged β-Arrestin-2. Activation of P2RY12 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PrecisION hKv4.3/hKChIP2 Recombinant Stable Cell Line, 2 vials. (CYL3069)
The PrecisION hKv4.3/hKChIP2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kv4.3/KChIP2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kv4.3/KChIP2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
ATCC AGS-Luc2; Gastric Adenocarcinoma; Human (Homo sapiens)
For-profit organizations: For every order of this item, you must provide a signed Material Transfer Agreement Addendum for Screening Application. We cannot ship this item until we receive this addendum. The person signing the addendum as the principal investigator must match the end user as listed on the applicable sales order for the item.Email the signed addendum to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your addendum will be reviewed, and this item will be released for shipment if all requirements are met. Additional fees may apply if this product is being used for a screening use (ATCC ACS-2103F), and these fees will be applied after your order is confirmed. If you need assistance with your order, please contact our Customer Care team.
Eurofins Discoverx ChemiScreen 5-HT4B Serotonin Receptor Membrane Preparation, 1 vial. (HTS110M)
The ChemiScreen 5-HT4B Serotonin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of HTR4B surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen NOP/ORL1 Opioid Receptor Membrane Preparation, 1 vial. (HTS040M)
The ChemiScreen NOP/ORL1 Opioid Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of OPRL1 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
ATCC Bacillus cereus; 6 x 0.3mL
ATCC 10876-MINI-PACK™ consists of 6 ready-to-use vials of ATCC 10876™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
Creative Bioarray KYSE180 CELLS, Human, Esophageal squamous cell carcinoma (ESCC), Epithelioid, Adherent monolayer, 90% RPMI-1640 + 10% heat-inactivated FBS, TP53 mutation, Doubling Time: 15.2 hours
KYSE180 CELLS, Human, Esophageal squamous cell carcinoma (ESCC), Epithelioid, Adherent monolayer, 90% RPMI-1640 + 10% heat-inactivated FBS, TP53 mutation, Doubling Time: 15.2 hours
Eurofins Discoverx PathHunter U2OS IL18R1/IL18RAP Dimerization Cell Line, 2 vials. (93-1131C3)
The PathHunter IL18R1/IL18RAP Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. IL-18) induced dimerization of IL18R1/IL18RAP receptors. This product uses EFC technology. The cell line included overexpresses IL18R1 target protein fused to PK alongside IL18RAP target protein fused to EA. Upon ligand-induced dimerization of IL18R1/IL18RAP, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/interleukins.
Eurofins Discoverx PathHunter CCR4 Total Internalization U2OS Cell Line, 2 vials. (93-0845C3)
The PathHunter CCR4 Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of CCR4 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged CCR4 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the CCR4 receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS GPR6 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0634C3)
The PathHunter GPR6 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR6 and EA-tagged β-Arrestin-2. Activation of GPR6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC 10 strain staggered mix; genomic material
NGS Standards are mock microbial communities that mimic mixed metagenomic samples. This product comprises genomic DNA prepared from fully sequenced, characterized, and authenticated ATCC Genuine Cultures that were selected on the basis of relevant phenotypic and genotypic attributes, such as Gram stain, GC content, genome size, and spore formation. NGS Standards enable the optimization of metagenomics workflows and research applications, providing reliable comparative data while improving assay consistency. Each order for this product is provided with access to run 20 analyses on One Codex, the leading bioinformatics platform for microbial genomics and metagenomics.
Immunology Consultants anti-Phospho Tau-231 Antibody - Monoclonal (Clone #100)
This monoclonal antibody provides highly specific detection of Tau phosphorylated at threonine‑231 (pTau‑231), a phosphorylation site linked to early Alzheimer’s pathology and synaptic dysfunction. Clone 100 delivers strong affinity and minimal nonspecific binding, supporting ELISA, Western blotting, immunohistochemistry, and biomarker assay development. MT231‑80A‑100 is ideal for studies examining Tau misfolding, phosphorylation kinetics, and early‑stage neurodegenerative changes. Its consistent lot‑to‑lot performance ensures reliable detection across CSF, plasma, and tissue‑based research samples.
Eurofins Discoverx PathHunter U2OS AXL Functional Assay, 2 vials. (93-1105C3)
The PathHunter U2OS AXL Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated AXL dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged AXL and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Eurofins Discoverx PathHunter CHO-K1 GPR103 β-Arrestin Cell Line, 2 vials. (93-0376C2A)
The PathHunter GPR103 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. QRFP-26) based activation of GPR103 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR103 and EA-tagged β-Arrestin-2. Activation of GPR103 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
