General Cell Lines and Cell Cultures
Amsbio LLC Human MIA Paca-2 / Luciferase & RFP Stable Cells
Human MIA Paca-2 / Luciferase & RFP Stable Cells
Abcam Astemizole, histamine H1 receptor antagonist and hERG K+ channel blocker, 10MG
MW 458.6 Da, Purity >99%. Potent, selective histamine H1 receptor antagonist (IC50 = 4 nM) and potent hERG K+ channel blocker (IC50 =0.9 nM). Orally active. Antiallergic agent. Active *in vivo* and *in vitro*.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter U2OS IL21R/IL2RG Dimerization Cell Line, 2 vials. (93-1035C3)
The PathHunter IL21R/IL2RG Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. IL-21) induced dimerization of IL21R/IL2RG receptors. This product uses EFC technology. The cell line included overexpresses IL21RG target protein fused to PK alongside IL2R target protein fused to EA. Upon ligand-induced dimerization of IL21R/IL2RG, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/interleukins.
ATCC Escherichia coli
Escherichia coli strain C has applications in resistance testing and the detection of coliphages in water and it can be used as a bacteriophage host.
ATCC Py8119; Breast Cancer; Mouse (Mus musculus)
PY8119 is a mesenchymal-like cell line that was isolated in 2004 from the mammary gland of an adult female mouse with adenocarcinoma. This cell line was deposited by L Ellies.
ATCC Quantitative Synthetic; Cryptosporidium; hominis DNA
Quantitative Synthetic Cryptosporidium hominis DNA can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine protozoan load. Preparation includes fragments from 18s rRNA, heat shock protein 70 (hsp70), COWP, GP60, dnaJ-like protein, and LIB13 regions.
ATCC Mycoplasma hominis; Strain PG21
Mycoplasma hominis strain PG21 [H 50, NCTC 10111] is a whole-genome sequenced bacterial type strain isolated from a rectal swab. This strain produces arginine deiminase.
Eurofins Discoverx ChemiScreen GIP Glucagon Receptor Membrane Preparation, 1 vial. (HTS134M)
The ChemiScreen GIP Glucagon Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of GIPR surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
ATCC Staphylococcus aureus; subsp. aureus
Staphylococcus aureus subsp. aureus strain FDA 209P is a whole-genome sequenced bacterium with applications in media testing, sterility testing, and susceptibility testing.
ATCC Corneal Epithelial Cell Growth Kit
Corneal Epithelial Cell Growth Kit (ATCC PCS-700-040) contains components that when added to Corneal Epithelial Cell Basal Medium (ATCC PCS-700-030) create a complete ATCC Primary Cell Solutions culture environment for corneal epithelial cells derived from a normal human cornea (e.g., Primary Corneal Epithelial Cells, Normal, Human, ATCC PCS-700-010). The serum-free medium formulation is designed to support normal corneal cell morphology, and promote rapid growth, and proliferation. No feeder layers, extracellular matrix proteins, or other substrates are required.
Quantitative Genomic RNA from Human respiratory syncytial virus strain 18537 (ATCC VR-1580DQ™)
Quantitative Genomic RNA from Human respiratory syncytial virus strain 18537 (ATCC VR-1580DQ™) is a molecular standard used for qPCR assay development, validation, and respiratory disease research. This product was derived from a virus isolated from a child with acute respiratory illness in Washington, DC.
Genscript Corporation CHO-K1/CCKA/G15 Stable Cell L
Cholecystokinin (CCK)-A and CCK-B receptors are highly homologous members of the seven transmembrane domain G-protein-coupled receptor super-family Peptides in the cholecystokinin (CCK) family have a variety of biological functions in the central and peripheral nervous systems as well as in the gastrointestinal tract The CCKA receptor has a more limited distribution with the highest densities in the hypothalamic nuclei areas of the hippocampus the septum dorsal motor vagal nucleus and interpeduncular nucleus of the brain stem It also occurs in numerous gastro-intestinal tissues Binding of ligands to CCK1 stimulates mobilization of intracellular calcium by activation of Gq/11 CCKA receptors affect satiety pancreatitis and gut motility and have growth-promoting effects on some tumors
ATCC Dengue virus type 2; Strain: TH-36
Dengue virus type 2 strain TH-36 is propagated in Aedes albopictus clone C6/36 cells (ATCC CRL-1660). This strain was isolated in 1958 from the serum of patient diagnosed with Thai hemorrhagic fever. This product has applications in vector-borne disease research.