General Cell Lines and Cell Cultures
ATCC Organoid Growth Kit 1F
ATCC Growth Kits are packages of recombinant proteins, small molecules and other supplements designed to make the preparation of complex media formulations for select organoid culture models easy and reliable. Kit components are supplied as powders to maximize stability and in convenient, pre-portioned, ready-to-reconstitute format that does not require aliquoting or storage once prepared.
Electron Microscopy Sciences Rodent Brain Matrix Rat Pup, 30g, Coronal
RBM allow the investigator to slice either coronal (perpendicular to center line) or sagittal (parallel to center line) sections through the brain at intervals as small as 1mm. All RBM's are identical and durable to insure reproducible sections in the day-to-day, year-to-year, or on a between laboratory basis.
Constructed from high grade zinc to allow for rapid temperature equilibration, easy cleaning, and sterilization. The matrices are designed to accommodate the brains of rodents placed ventral side up. The channels are precisely cut at 1 mm intervals and 0.3 mm wide.
Size: 30g
Type: Coronal
STEMCELL Technologies Plerixafor Mobilized Human Peripheral Blood Mononuclear Cells, Frozen, Size: 5 x 10^6 cells
Start your assays with ready-to-use, ethically sourced, mobilized primary mononuclear cells. We help you get the cells you need with personalized service, custom products, flexible delivery times, and the option to reserve entire lots to prescreen cells for applications. Donors are mobilized with G-CSF, plerixafor, or G-CSF and plerixafor prior to collection. Isolated from leukapheresis samples using density gradient separation or red blood cell lysis and cryopreserved in CryoStorCS10 medium, cells are obtained using Institutional Review Board (IRB)-approved consent forms and protocols. Additional documentation and high-resolution HLA typing (Class I and Class II alleles and CMV status) are available upon request. ACDA is added as an anticoagulant. Contact techsupport@stemcell.com for donor specifications (BMI category, smoking status, ethnicity, etc.). Donors are screened for HIV-1, HIV-2, hepatitis B, and hepatitis C. Certain products are only available in select territories.
STEMCELL Technologies Human Whole Peripheral Blood Collected with EDTA, Fresh, Size: 80 mL
Normal whole peripheral blood (PB) is obtained from healthy donors using Institutional Review Board (IRB)-approved consent forms and protocols. Acid citrate dextrose, solution A (ACDA), Sodium Heparin (Na-Hep), Ethylenediaminetetraacetic acid (EDTA), or Citrate-phosphate-double-dextrose (CP2D) is the anticoagulant.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information and to inquire about donor selection or information including BMI category, smoking status, ethnicity, etc.Browse our Frequently Asked Questions (FAQs) (https://www.stemcell.com/primary-cells-faq) on Primary Cells.
Biochain Institute Inc Paraffin Tissue Section - Multiple Sclerosis Disease: Brain: Frontal Lobe, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Amsbio LLC STAT6 Leeporter™ Luciferase Reporter-Ba/F3 Cell Line
STAT6 Leeporter™ Luciferase Reporter-Ba/F3 Cell Line
ABclonal Technology HRH4 Rabbit pAb
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene.
Eurofins Discoverx PathHunter PRLHR Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0766C3)
The PathHunter PRLHR Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of PRLHR via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged PRLHR. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting PRLHR-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Cayman Chemical 9-cIs RetInal 5mg
A natural retinoid that is produced by oxidation of 9-cis retinol by cRDH; binds to CRBP-I, CRBP-II, and CRALBP (Kds = 8, 5, and 53.3 nM, respectively); inhibits differentiation of RCJ C5.18 chondrogenic cells into cartilage in vitro (IC50 = 8 nM); it rescues cone ERG responses in Irbp-/- mice (0.375 mg)
ATCC Pfizer Pneumococcal polysaccharide powder Type 3 (d3) 200mg
Purified pneumococcal polysaccharide type 3 is manufactured by Pfizer, Inc., for small-quantity distribution by ATCC. The pneumococcal powder type 3 is a component of the current 13-valent vaccine against Streptococcus pneumoniae. The pneumococcal polysaccharide type 3 can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Montana Molecular Human Succinate Receptor (SUCNR1, SUCR1) BacMam, 30mL
Use this assay to express the human Succinate receptor in your cells of interest. BacMam packaging provides efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in primary or iPSC-derived cells. Importantly, BacMam expression is easily titrateable to suit your experimental needs. This tool can be co-expressed with Montana Molecular's assays for cAMP to investigate signaling dynamics at the SUCNR1 receptor.
Amsbio LLC TLR8/NF-kB Leeporter™ Luciferase Reporter-HEK293 Cell Line
TLR8/NF-kB Leeporter™ Luciferase Reporter-HEK293 Cell Line
Eurofins Discoverx PathHunter CHO-K1 GHSR1b β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0354C2A)
The PathHunter GHSR1b cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ghrelin) based activation of GHSR1b GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GHSR1b and EA-tagged β-Arrestin-2. Activation of GHSR1b stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 GPR25 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0368C2A)
The PathHunter GPR25 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR25 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR25 and EA-tagged β-Arrestin-2. Activation of GPR25 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen α2A Adrenergic Receptor Membrane Preparation, 1 vial. (HTS096M)
The ChemiScreen α2A Adrenergic Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of ADRA2A surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.