General Cell Lines and Cell Cultures
Promocell GmbH PromoCell NHDF-c 500,000 Human Dermal Fibroblasts, adult, cryopreserved
Primary Normal Human Dermal Fibroblasts (NHDF) are isolated form the dermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen, and the thighs.They can be used for wound healing studies and dermatological research to investigate diseases like scleroderma, fibrosarcoma, fibrosis, xeroderma pigmentosum, and histiocytoma. Moreover, fibroblasts are important for cancer research, tissue regeneration, and tissue engineering studies.
AllCells LLC Leukopak- Cryopreserved- 2.5-3.0B Cells- (5 bags from the same donor)
Leukopak- Cryopreserved- 2.5-3.0B CellsAll Cryopreserved Leukopaks are quality controlled for cell count and viability (pre-cryopreservation) using a validated AO/PI protocol. Additional characterization such as immunopheno-typing based on cell surface marker expression (CD45+- CD3+- CD4+- CD8+- CD14+- CD56+- CD19+) and 5-part differential CBC counts will be provided. This price reflects a 5 bag purchase (all from the same donor).
Biochain Institute Inc Paraffin Tissue Section Array - Human Adult Normal Tissue, Array I (64 Specimens), 5 slides/PK
BioChain's tissue arrays or tissue microarrays (TMAs) are a useful tool in biomarker research and drug target validation. It consists of paraffin blocks that are assembled in array fashion to allow multiplex histological analysis. BioChain's TMAs provide a valuable tool for analysis of protein, RNA, or DNA molecules in oncology, both the malignant and metastatic markers. TMAs can also be constructed with tissues from other diseases and species.
Eurofins Discoverx cAMP Hunter CHO-K1 CXCR2 (IL8RB) Gi Cell Line, 2 vials. (95-0074C2)
The cAMP Hunter CXCR2 (IL8RB) Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL8/IL8) based activation of CXCR2 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CXCR2, a naturally Gi/Go coupled GPCR. Upon activation of CXCR2, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS TYRO3 Functional Assay, 2 vials. (93-1110C3)
The PathHunter U2OS TYRO3 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated TYRO3 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged TYRO3 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC Rhodospirillum rubrum
Rhodospirillum rubrum strain NCIB 8255 is a whole-genome sequenced type strain. This phototroph is tolerant to oxygen, so strictly anoxic conditions are not required when the vial is thawed.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Brain: Midbrain, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Lonza Walkersville Rat Embryonic Dorsal Root Ganglion (eDRG) Neurons
Ready to use Rat Embryonic Dorsal Root Ganglion (DRG) Neurons are suspensions of high quality sensory neurons prepared by standardized methods, and are ready for immediate culture.Benefits:Ready-To-Use No tissue dissection or animal handling required Increased data reproducibilityCharacteristic morphology and staining tests confirm tissue origin and cell typeNegative for mycoplasma, bacteria, yeast and fungiCertificate of Analysis (CoA) is available for every batch Applications:NeurogenesisNeurotransmitter FunctionGene ExpressionSignaling PathwaysElectrophysiologyNeurotoxicityDrug/Compound ScreeningAdvanced Cell Culture ModelsContent:≥ 1,000,000 cryopreserved cells per ampule
Lonza Walkersville hMSC Adipogenic Induction Kit
hMSC Adipogenic Induction SingleQuots Kit is a component of the hMSC Adipogenic Differentiation BulletKitTM and is available separately Stem cells possess the unique ability to differentiate into multiple lineages of cells including adipocytes Lonza s hMSC Adipogenic Differentiation BulletKitTM Medium is a serum containing media system designed to induce adipogenic differentiation of human bone marrow derived mesenchymal stem cells into mature functionally active adipocytes in as few as 19 days Differentiation can then be validated by a variety of methods including the use of Lonza s AdipoRedTM Adipogenic Assay Reagent which provides a quantitative value related to the amount of adipogenic differentiation
ATCC A-431; Epidermoid Carcinoma; Human (Homo sapiens)
A-431 is a cell line exhibiting epithelial morphology that was isolated from the epidermis of an 85-year-old female patient with epidermoid carcinoma. This cell line is one of a series of cell lines established from solid tumors by D.J. Giard, et al. and can be used in cancer, toxicology, and immuno-oncology research.
ATCC TM3; Testis; Mouse (Mus musculus)
TM3 is a Leydig cell that was isolated from a male mouse. This cell line was deposited by JP Mather.
Eurofins Discoverx PathHunter CHO-K1 OPRM1 β-Arrestin Cell Line, 2 vials. (93-0213C2)
The PathHunter OPRM1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. met 5-enkephalin) based activation of OPRM1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRM1 and EA-tagged β-Arrestin-2. Activation of OPRM1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ACROBiosystems CHO/Human CD16a (FcγRIIIa) 158V Stable Cell Line (High Expression), 2 vials
This CHO-derived stable cell line expresses full-length human CD16a (FcγRIIIa) carrying the 158V variant at high levels. Supplied frozen in cryopreservation medium as two vials (1 mL per vial), the cell line is intended for cell-based assays that require CD16a-dependent binding or antibody crosslinking, for example co-culture with 4-1BB reporter cells to evaluate agonist activity. Culture and selection conditions are provided in the product datasheet.
- High expression of full-length human CD16a (158V) for robust assay readouts.
- Adherent CHO host suitable for standard cell culture workflows.
- Supplied frozen with at least 5x10^6 cells per 1 mL vial.
- Hygromycin B selection marker for stable maintenance (20 μg/mL).
- QC tested: mycoplasma negative and sterility tested.
- Optimized growth conditions provided (F-12K + 10% FBS).
ATCC Nocardia nova; Strain UT_1954_0606
Nocardia nova strain UT_1954_0606 was isolated in 1988 from a human in Texas. It has applications as a CLSI quality control organism for broth microdilution susceptibility testing of Nocardia species.