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Mouse Serum:Preservative FreeProduct Form; Whole serum - liquidPreparation; Normal mouse serum, 0.2um filtered. Prepared from barrier mice which are screened for infectious agents.Preservative Stabilisers; None presentStorage; Store at -20oC only. This product should be stored undiluted.Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the product. Should this product contain a precipitate we recommend microcentrifugation before use
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A STING agonist (EC50 = 2.1 µM in a reporter assay); selective for STING over a panel of 468 kinases; increases plasma IFN-β and IL-6 levels in mice at 30 mg/kg; increases the intratumor frequency of CD69+CD8+ T cells, reduces tumor growth, and increases survival in a B16/F10 murine melanoma model
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