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Cayman Chemical LevonrdefrIn 50mg
A vasoconstrictor; (–)-enantiomer of nordefrin; rapidly increases blood pressure and heart rate in anesthetized dogs (1-5 UG/kg); in combination with mepivacaine, increases systolic arterial blood pressure in anesthetized dogs (0.514 and 1.542 mg/kg)
Cayman Chemical MoguIsteIn 100mg
A peripherally acting antitussive agent; inhibits the citric acid-induced cough reflex in conscious guinea pigs but not the cough reflex induced by electrical stimulation of the afferent superior laryngeal nerve in anesthetized guinea pigs (ED50s = 5.5 and >20 mg/kg, respectively); prevents BALF eosinophil and neutrophil infiltration in an ovalbumin-sensitized guinea pig model of allergic airway inflammation; inhibits increases in tracheal and bronchial plasma exudation induced by cigarette smoke in anesthetized guinea pigs at 30 mg/kg
Cayman Chemical NSuccInImIdylSACtylthIoac 50mg
A protein-modifying agent; introduces sulfhydryl groups to proteins; used in conjunction with the protein cross-linking reagent SMCC in the conjugation of proteins with IgG antibodies for use in ELISAs
Cayman Chemical Linolenic ACD ethyl esTR 100mg
An esterified version of GLA which is less water soluble but more amenable for the formulation of GLA-containing diets
Cayman Chemical ScutelareIn 50mg
A flavone; has antioxidant activity in a TRAP assay at 1 μg/ml; inhibits sucrose hydrolysis by rat intestinal α-glucosidase and ATPase activity of the SARS coronavirus helicase nsP13 (IC50s = 12 and 0.86 μM, respectively); decreases LPS-induced NO release and iNOS and TNF-α mRNA expression in RAW 264.7 macrophages at 50 μM; decreases tumor weight and volume in an HT-1080 human fibrosarcoma mouse xenograft model at 0.5 μg/g
Cayman Chemical GInkgotoxIn 50mg
A pyridoxine antimetabolite; inhibits pyridoxal kinase (Ki = 3 µM); induces seizure-like behavior in zebrafish larvae at 200-1,000 µM
Cayman Chemical NtrIdecnoylLHomoserIn la 50mg
An N-acyl homoserine lactone; has been found in Y. pseudotuberculosis
Cayman Chemical MaytnsInol 100mg
An ansa macrolide; inhibits polymerization and induces depolymerization of bovine brain tubulin (EC50s = 12 and 43 µM, respectively); inhibits sea urchin egg mitosis at 10 µM and decreases proliferation of KB nasopharyngeal cancer cells (EC50 = 0.19 UG/ml)
Cayman Chemical SmethylLThIocItrulInhy 100mg
S-methyl-L-Thiocitrulline is a potent NOS inhibitor with selectivity toward the neuronal isoform compared to eNOS and iNOS. For human enzymes, it exhibits Ki values of 1.2, 11, and 40 nM for nNOS, eNOS, and iNOS, respectively.{1325,1293}
Cayman Chemical NaBenzoylLArgInInpNAhy 100mg
A colorimetric substrate for trypsin and papain; enzymatic cleavage releases pNA, which can be quantified by colorimetric detection at 405 nm as a measure of trypsin or papain activity
Cayman Chemical Mornteltartrate 100mg
A positive allosteric modulator of nAChRs; enhances channel gating of the α3β2 nAChR subtype
Cayman Chemical SucInIMDyl 4formylbenzoat 50mg
A heterobifunctional building block; has been used in the conjugation of oligonucleotides to antibodies for protein detection, as well as in the synthesis of fluorescent BODIPY-etoposide
Cayman Chemical S-PhenylmercapturIc AcId 50mg
A metabolite of benzene; used as a biomarker for benzene exposure; urinary concentrations up to 543 UG/g creatinine have been detected
Cayman Chemical 2-PhenthylamInhydrochlorI 50mg
A natural monoamine alkaloid that acts as neuromodulator in the central nervous system; stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases as well as other enzymes; intended for forensic and research applications
Cayman Chemical 2-ThIourIdIn 50mg
A modified nucleobase found in tRNAs that is known to stabilize U:A pairs