Human Sera
Cayman Chemical PalmItoylLcarnItInchLRI 50mg
A long-chain acylcarnitine; delivers palmitate into the mitochondria for fatty acid oxidation and energy production; inhibits lecithin:cholesterol acyltransferase activity in isolated rat plasma at 500 µM; serum and hepatic levels are increased in mice during cold exposure; protects against age-induced cold sensitivity in mice
Cayman Chemical lnoelaIdIc ACD mthyl STR 50mg
An esterified form of linoelaidic acid; has been found in H. sabdariffa essential oil as well as biodiesel produced from sea mango seed oil
Cayman Chemical trns-nrolIdol 50mg
A sesquiterpene with diverse biological activities; inhibits the growth of S. aureus, B. subtilis, E. coli, and S. cerevisiae; reduces viability of CaCo-2 adenocarcinoma cells (IC50 = 28.7 mg/L); insecticidal against A. aegypti (LC50 = 9 mg/L)
Cayman Chemical LGulanosylcaldarchaetidyl 50mg
The main polar lipid of the archaeon T. acidophilum; cellular levels of β-L-gulopyranosyl-caldarchaetidyl-glycerol in T. acidophilum HO-62 positively and negatively correlate with increases in culture pH and temperature, respectively; has been used as a standard for the quantification of polar lipids extracted from T. acidophilum HO-62
Cayman Chemical FluorescamIn 50mg
An amine-reactive fluorescent probe; has commonly been used as a reagent in fluorometric protein assays; has commonly been used as a reagent in fluorometric protein assays; displays excitation/emission maxima of 370/488 nm, respectively, in acetone
Cayman Chemical trns-nrolIdol 100mg
A sesquiterpene with diverse biological activities; inhibits the growth of S. aureus, B. subtilis, E. coli, and S. cerevisiae; reduces viability of CaCo-2 adenocarcinoma cells (IC50 = 28.7 mg/L); insecticidal against A. aegypti (LC50 = 9 mg/L)
Cayman Chemical DInIconazole 100mg
A triazole fungicide; inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol; fungicidal against B. cinerea, S. fimicola, F. graminearum, S. cepivorum, and B. sorokiniana (EC50s = 0.012, <0.001, 0.008, 0.02, and 0.06 mg/l, respectively); decreases height and leaf area in bean plants when applied to roots at 5 mg/l; exhibits dose-dependent toxicity in zebrafish
Cayman Chemical Beclomethason 100mg
A glucocorticoid; reduces plasma corticosteroid levels in rats from 1-10 mg/kg
Cayman Chemical 5 6 7-TrImethoxyflavon 100mg
A flavonoid with diverse biological activities; reduces the viability of HepG2 and Hep3B carcinoma cells at 50 µM; decreases HSV-1 and poliovirus replication in HSV-1- or poliovirus-infected Vero cells, as well as decreases CMV replication in CMV-infected MRC-5 cells (IC50s = 3.2, 32, and 8 mg/L, respectively); inhibits LPS-induced NO, PGE2, Tnf-α, Il-1β, and Il-6 production in RAW 264.7 macrophages at 20 or 40 µM; increases survival in a mouse model of LPS-induced sepsis at 40 mg/kg
Cayman Chemical MT-1207hydrochlorIde 50mg
An α1-adrenergic and 5-HT2A receptor antagonist (IC50s = 2A- and α2B-adrenergic and 5-HT1A, 5-HT1B, 5-HT2B, and 5-HT2C receptors (IC50s = 18.1, 4.89, 4.68, 41, 11.5, and 26 nM, respectively), among others; decreases systolic and diastolic blood pressure and heart rate in spontaneously hypertensive rats and 2K-1C renal hypertensive dogs at 10 and 4 mg/kg, respectively
Cayman Chemical GlutamInase-IN-3 100mg
An inhibitor of GAC (IC50 = 0.24 µM); inhibits the proliferation of PC3 and LNCaP prostate cancer cells (IC50s = 6.14 and 2.13 µM, respectively) and non-cancerous CCD-1072Sk fibroblasts (IC50 = 15.39 µM)
Cayman Chemical SemaglutIdesodIum salt 100mg
A GLP-1R agonist (EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor); decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = <2 nmol/kg); prevents decreases in the number of dopaminergic neurons in the substantia nigra and increases in lipid peroxidation in the substantia nigra and striatum, as well as improves motor coordination in the rotarod and footprint tests in a mouse model of Parkinson’s disease induced by MPTP at 25 nmol/kg; decreases neuronal loss in the hippocampal dentate gyrus and CA1 and CA3 regions and improves motor coordination and grip strength in the beam-walking and hanging wire tests, respectively, in a rat model of stroke induced by permanent MCAO at 10 nmol/kg every other day
Cayman Chemical 4-AcetamIdo ntIpyrIn 50mg
An active metabolite of metamizole; inhibits β-galactosidase activity, a marker of LXRα activity, in a yeast two-hybrid assay (IC20 = 79.9 µM); has been found as a micropollutant in reclaimed wastewater
Cayman Chemical HValProProOHtrIfluoroac 50mg
A peptide ACE inhibitor (IC50 = 9 µM); inhibits acetylcholine-induced NO production in HUVECs at 1 µM; induces vasorelaxation in precontracted isolated rat aortic rings; decreases systolic blood pressure in spontaneously hypertensive rats at 0.3 mg/kg; dietary administration reduces plasma levels of total cholesterol, HDL-cholesterol, and triglycerides, expression of Il6 and Il1b, and aortic arch intimal thickening and atherosclerotic plaque formation in ApoE-/- mice