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Human sera and related serum-derived preparations are used in cell culture, immunoassays, and other laboratory research. Depending on the preparation, they may supplement culture media or serve as blocking reagents and assay controls.
A diterpene with diverse biological activities; a TRPV3 activator (EC50 = 16 µM for inducing calcium influx in HEK293 cells expressing TRPV3); inhibits IκBα degradation in TNF-α-stimulated HeLa cells at 60-140 µM; reduces amyloid-β (25-35) peptide-induced apoptosis, increases in MDA levels, and the production of ROS; reduces paw edema in a mouse model of hind paw inflammation at 50 mg/kg; has anxiolytic and antidepressant-like activity in mice
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A purported binding agent of filamin A; the data regarding PTI-125 have prompted expressions of concern by the journals in which the data were published
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A psychotropic compound of the phenethylamine and cathinone classes; slightly less potent than methcathinone and essentially equipotent with cathinone, in behavioral studies involving rats; intended for forensic purposes
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An analytical reference standard categorized as an amphetamine; has been found as an AAF during anti-doping testing; intended for research and forensic applications
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A stereoisomer of IP6; identified in soil samples from Madagascar, New Zealand, and the Falkland Islands and in freshwater sediment from Danish lakes; has been used as a negative control for the stereospecific effects of myo-inositol hexakisphosphate on IK,in in intact guard cells
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