Human Sera
Cayman Chemical SureLIghtPerCP CynIn 5 5 50mg
SureLight™ PerCP Cyanine 5.5 is a fluorescent probe used in protein detection Excitation max. λ: 496 nm Emission max. λ: 517 nm Uses: Custom antibody labeling, fluorescence-activated cell sorting, flow cytometry, Luminex, and T cell labeling
Cayman Chemical GastrodIa elta Gastrodn 50mg
A phenolic glycoside with diverse biological activities; reduces Aβ42-induced cell death of rat hippocampal neurons and BV-2 mouse microglia; improves learning and memory in various transgenic mouse models of Alzheimer's disease; reduces motor deficits and loss of dopaminergic neurons in a rat model of Parkinson's disease; reduces seizure duration and intensity in a rat model of pentylenetetrazole-kindling chronic epileptic seizures from 50-200 mg/kg; increases social interaction and decreases marble burying and grooming behaviors, as well as restores inhibitory synaptic transmission and GAT1 and α5 subunit-containing GABAA expression in the basolateral amygdala in a mouse model of valproic acid-induced autistic-like phenotypes at 100 mg/kg; increases biomechanical bone strength in a rat model of dexamethasone-induced osteoporosis; inhibits ethanol-induced hepatocellular apoptosis and restores liver function in a rat model of alcoholic liver disease
Cayman Chemical ZINC00881524 100mg
A ROCK inhibitor; decreases levels of ROCK1 in T47D and CAMA-1 breast cancer cells; decreases proliferation of T47D and CAMA-1 cells when used in combination with CNN1 knockdown
Cayman Chemical 9-EthylgunIn 50mg
A model nucleobase that is used to study DNA interactions with organometallic complexes, especially those designed to target tumors
Cayman Chemical 14-PentadecenoIc AcId 100mg
A 15-carbon, long-chain fatty acid that contains an alkene functional group on the terminal carbon of its aliphatic tail
Cayman Chemical Butenoyl PAF 50mg
A product of the oxidative decomposition of 2-arachidonoyl phospholipids; 10-fold less potent than PAF as a PAF receptor agonist, but present in amounts 100-fold greater
Cayman Chemical 4methoxyaPyrroldInopentIo 50mg
Shares structural features with the stimulant α-PVP, whose mechanism of action is unknown but is believed to act similarly to the designer drug MDPV
Cayman Chemical BU 224hydrochlorIde 50mg
An imidazoline receptor agonist; selectively binds to imidazoline I1 and -I2 receptors over a2-ARs (IC50s = 0.034, 0.026, and 15 µM, respectively); reduces complete Freund’s adjuvant-induced thermal and mechanical hyperalgesia in rats at 10 or 17.8 mg/kg; decreases the latency to seizure onset and increases the percentage of animals with grade V seizures to a greater extent in female than male mice; reverses cognitive deficits in the 5XFAD transgenic mouse model of Alzheimer’s disease at 5 mg/kg
Cayman Chemical 5bromo3IndolylDGalacto 100mg
A chromogenic substrate for β-galactosidase; upon enzymatic hydrolysis, it generates an indigo-colored precipitate that can be used to measure β-galactosidase activity; has been used to detect β-galactosidase in muscle from E. coli lacZ-expressing transgenic mice
Cayman Chemical 5Cyno2 3dI ptolyltetra 100mg
A redox-sensitive tetrazolium salt used primarily to detect metabolic activity in microorganisms; readily taken up by living cells and reduced by respiratory activity to produce a red fluorescent, water-insoluble formazan crystal (absorption maximum at 450 nm)
Cayman Chemical RauwolscInhydrochlorIde 100mg
A natural alkaloid that acts as a selective and reversible α2-adrenergic receptor antagonist (Ki = 12 nM); also acts as a receptor antagonist at the serotonin 5-HT2B receptor (Ki = 14.3 nM)
Cayman Chemical -O-Desmethyl VenlafaxIn 50mg
An active metabolite of venlafaxine; inhibits NET and SERT (IC50s = 47.3 and 531.3 nM, respectively); selective for NET and SERT over 50 non-transporter targets; increases extracellular NE in the male rat hypothalamus and 5-HT in the same region when used in combination with WAY-100635; reduces immobility time in the forced swim test in a rat model of cognitive deficits and depression induced by MI when compared with MI-vehicle control animals 16 weeks following MI; improves learning in the passive avoidance step-down test two weeks following MI compared to MI-vehicle control rats and spatial memory in the Morris water maze 16 weeks following MI
Cayman Chemical Linolenic ACD 100mg
γ-Linolenic acid is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. γ-Linolenic acid produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.{2361}
Cayman Chemical NDemethylvncomycInhydroch 50mg
A glycopeptide antibiotic; active against several strains of S. aureus and S. epidermidis in vitro and in vivo