Human Sera
Cayman Chemical 5 NCyclopropylcarboxamIdo 50mg
A specific adenosine A2 receptor agonist with antipyretic and anticonvulsant activity; stimulates the production of cyclic AMP in CHO-K1 cells with an EC50 value of 5.3 µM
Cayman Chemical DEA Nonate 50mg
A NO donor with a half-life of 2 minutes at 37°C, pH 7.4; liberates 1.5 moles of NO per mole of parent compound
Cayman Chemical LValacyclovIrhydroCLOrID 100mg
A prodrug of acyclovir; inhibits HSV-I replication (IC50 = 0.84 µM); rapidly converted to acyclovir in vivo; active against varicella-zoster and Epstein-Barr viruses in vitro (IC50s = 1.3-20.6 and 0.3-25 µM, respectively)
Cayman Chemical 5 7 3 4 5Pentamethoxyflav 50mg
A flavonoid with diverse biological activities; inhibits pancreatic lipase in a cell-free assay; reduces lipid accumulation in 3T3-L1 adipocytes; inhibits transactivation of Nrf2 in a reporter assay using HEK293T cells at 10, 25, or 50 µM; sensitizes cisplatin-resistant A549 NSCLC cells to cisplatin; inhibits LPS-induced NO production in RAW 264.7 macrophages and GES-1 cells; decreases blood glucose levels and renal fibrosis in a rat model of STZ-induced diabetes at 5 mg/kg
Cayman Chemical BucladesInsodIum salt 100mg
A cell-permeable, cyclic nucleotide derivative that mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor
Cayman Chemical IpronIdazole 50mg
A nitroimidazole antiprotozoal agent; dietary administration reduces H. meleagridis-induced mortality in young turkeys from 0.00312-0.0094% w/w; induces 100% disease clearance in bulls infected with T. foetus at 60 g/animal
Cayman Chemical OxalIplatIn 50mg
A DNA-crosslinking agent; induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein crosslinks, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells; is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2.7 µM, respectively); reduces tumor growth in an HCCLM3 mouse xenograft model at 5 or 10 mg/kg once per week
Cayman Chemical TrIamcInolon acetonIde 100mg
A synthetic corticosteroid; decreases cytokine levels, the firing rate of sensory neurons, and mechanical hypersensitivity in a rat spinal nerve ligation model at 1.5 mg/kg administered prior to and following surgery for three days; decreases outflow facility in a mouse model of steroid-induced glaucoma when 20 µl of a 40 mg/ml suspension is administered subconjunctivally
Cayman Chemical Maltopentaose 50mg
An oligosaccharide comprised of five α-1,4-linked glucose molecules; increases the α-amylase synthesis rate in B. stearothermophilus at 1 mM; has been used as a substrate for PPA to study various inhibitors of PPA
Cayman Chemical 1PalmItoyl2Oleoylsnglyce 100mg
Phospholipids used for liposome production in order to study the properties of lipid bilayers
Cayman Chemical 1 5-IsoquInolIndIol 100mg
An inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50 = 0.39 μM); can be used with cells in culture and in animals
Cayman Chemical LabetalolhydrochlorIde 50mg
An analytical reference standard categorized as a β-adrenergic receptor antagonist; has been used as a doping agent in sports; intended for use in analytical forensic applications
Cayman Chemical CefotetnsodIum salt 100mg
A cephamycin antibiotic; active against Gram-positive and Gram-negative bacteria (MICs = 0.03-32 mg/ml); reduces mortality by 50% in a rabbit model of fecal peritonitis (25 mg/kg twice daily)
Cayman Chemical 2MethylmethcathInonhydroc 50mg
An analytical reference standard categorized as a cathinone; a potential impurity in the synthesis of 4-methylmethcathinone; intended for research and forensic applications