Human Sera
Cayman Chemical MndIpropamId 50mg
A biotinylated form of H10 has been used in ELISA and co-immunoprecipitation assays to assess AGR2 levels in cancer cells
Cayman Chemical TndospIron 50mg
A peptide substrate of PKC has been used to monitor PKC activity in primary bovine retinal endothelial cells
Cayman Chemical Aranidipine 50mg
An antimicrobial peptide induces apoptosis in C. albicans at 5 UM active against the E. coli strain CFT073 (MIC 100 Ug/ml) increases survival of CFT073-infected G. mellonella larvae decreases enrichment of the gut microflora Bacteroidaceae and Enterobacteriaceae and increases gut levels of Lactobacillus as well as increases survival and decreases body weight loss in a mouse model of DSS-induced IBD
Cayman Chemical Reagent 2R2 2mL
An antimicrobial cationic peptide active against the bacteria E. coli K. pneumoniae S. epidermidis S. aureus and the fungus C. albicans (MICs 5 10 10 50 and 80 Ug/ml respectively) reduces germination percentage and mean tube elongation in kiwi fruit pollen at 20 UM decreases viral replication in Vero cells infected with herpes simplex virus 1 (HSV-1) or HSV-2 (EC50s 22.16 and 19.8 UM respectively) without affecting cell viability (CC50 100 UM)
Cayman Chemical GuvacInhydrochlorIde 50mg
A cell-permeable inhibitor of caspase-3 activation blocks apoptosis in a variety of cell lines induced by different stimuli including Fas ligand and etoposide
Cayman Chemical 1mthyl1 4dIhydronIcotInam 50mg
An NSAID that inhibits both isoforms of COX (IC50s 1 1 and 8 7 UM for COX-1 and COX-2 respectively)
Cayman Chemical CefotetnsodIum salt 100mg
Contains deuterated forms of ( )12(13)-DiHOME 13(S)-HODE 13-OxoODE and ( )12(13)-EpOME each of which have been shown to be involved in the physiological or pathological responses related to cell proliferation or oxidative burst and are potential markers for (or potential contributors to) various human diseases
Cayman Chemical SaxaglIptInhydrochlorIde 50mg
A monosaccharide component of glycosaminoglycans including heparin conformationally flexible allowing it to bind metal ions and may be important for the antithrombotic activity of heparin
Cayman Chemical Pralatrexate 50mg
A potent inhibitor of ALK5 (IC50 12 9 nM) also inhibits ALK2 and ALK4 at nanomolar concentrations used to block TGF-B signaling and EMT in animal models of cancer and fibrosis
Cayman Chemical ChlorpyrIfos 50mg
A naturally occurring O-methylated phenolic acid that can be enzymatically degraded by some bacteria as a source of methane or methanol inhibits aldose reductase (IC50 213 Ug/ml) proteasome activity and cancer cell proliferation
Cayman Chemical MetaramInoltartrate 100mg
A reversible inhibitor of COMT (Ki 0 27 nM for human recombinant COMT) crosses the blood brain barrier and inhibits both peripheral and central COMT activity
Cayman Chemical TrImethadIon 50mg
An analytical reference standard categorized as a piperazine intended for research and forensic applications
Cayman Chemical Arformoteroltartrate 50mg
A disaccharide containing two glucose subunits joined by an a-(1 6) linkage
Cayman Chemical CIsatracurIumbesylate 50mg
A retinoid and an active metabolite of the retinoid etretinate that has antiproliferative activities binds to CRABP-1 and CRABP-II (Kds 3 and 15 nM respectively for the mouse recombinant proteins) but has low affinity for human recombinant retinoic acid receptor-retinoid X receptor (RAR-RXR) heterocomplexes inhibits proliferation (IC50 6 6 UM) and suppresses TNF-a- and IFN-Y-induced protein levels of STAT1 NF- B and RANTES in HaCaT keratinocytes when used at 50 UM inhibits proliferation of HL-60 SCC4 SCC15 and A431 but not MCF-7 cancer cells at 30 UM decreases the severity of psoriatic-like skin lesions in K14-VEGF transgenic mice (20 Ug per mouse)
Cayman Chemical Etofenamate 50mg
An inhibitor of AB oligomerization and fibrillization (IC50 50 nM for formation of fibrils from AB1-42) reduces the cytotoxic effect of AB oligomers in a cultured neuronal cell line