Primary Antibody Matched Pairs
ABclonal Technology UCKL1 Rabbit pAb
The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants.
ABclonal Technology KD Validated PTBP1 Rabbit mAb
This gene encodes a protein in the heterogeneous nuclear ribonucleoprotein (hnRNP) subfamily which includes RNA-binding proteins that interact with heterogeneous nuclear RNA (hnRNA) These proteins influence pre-mRNA processing and other mRNA metabolism and transport processes While primarily located in the nucleus some hnRNPs shuttle between the nucleus and cytoplasm The encoded protein contains four quasi-RNA recognition motif (RRM) domains that bind RNAs particularly intronic polypyrimidine tracts involved in pre-mRNA splicing It may also facilitate U2 snRNP binding to pre-mRNAs and is involved in the ubiquitin-proteasome degradation pathway This protein is found in the nucleoplasm and perinucleolar structures Alternative splicing generates multiple isoforms
ABclonal Technology PE anti-Human CD96/TACTILE
The protein encoded by this gene belongs to the immunoglobulin superfamily It is a type I membrane protein The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response It may also function in antigen presentation Alternative splicing generates multiple transcript variants encoding distinct isoforms
ABclonal Technology Uromodulin/UMOD Rabbit mAb
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2) glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI) and familial juvenile hyperuricemic nephropathy (FJHN) Alternative splicing of this gene results in multiple transcript variants