Primary Antibody Matched Pairs
Biotium CD79b (B-Cell Marker)(B29/123), CF740 conjugate, 0.1mg/mL
CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium S100A9(S100A9/1075), CF405S conjugate, 0.1mg/mL
This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylate
![ABclonal Technology [KO Validated] ABCF2 Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000097414.jpg-250.jpg)
ABclonal Technology [KO Validated] ABCF2 Rabbit pAb
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. Alterations in this gene may be involved in cancer progression. Related pseudogenes have been identified on chromosomes 3 and 7.
Biotium CD70(TNFS7/1026), 0.2mg/mL
This antibody recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
ABclonal Technology FGL2 Rabbit pAb
The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.
Miltenyi Biotec, Inc. CD96 (TACTILE)-PE-Vio770,h, REA195,100 t
Identification and enumeration of CD96 (TACTILE)+ cells by flow cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
ABclonal Technology NUP98 Rabbit mAb
This gene encodes a 186 kDa precursor protein that is part of the nucleoporin family and plays a key role in nuclear pore complexes (NPCs) which regulate macromolecule transport between the nucleus and cytoplasm The precursor undergoes autoproteolytic cleavage to generate two nucleoporins a 98 kDa nucleoporin containing a Gly-Leu-Phe-Gly (GLGF) repeat domain involved in nuclear import export mitotic progression and gene expression regulation and a 96 kDa nucleoporin which serves as a scaffold component of the NPC Proteolytic cleavage is crucial for targeting these proteins to the NPC Gene translocations have been linked to various leukemias creating chimeras with the GLGF domain fused to partner genes Alternative splicing results in multiple isoforms some lacking the 96 kDa nucleoporin region
ABclonal Technology ENO1 Rabbit pAb
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.
ABclonal Technology BMP7 Rabbit pAb
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients.
ABclonal Technology TNFRSF6B Rabbit pAb
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript.
Sino Biological Recombinant Human KIR3DL1 Protein (ECD, hFc Tag), HPLC-verified
A DNA sequence encoding the Human KIR3DL1 (P43629) (Met1-His340) was expressed with the Fc region of human IgG1 at the C-terminus.
![ABclonal Technology [KO Validated] ANXA1 Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000115167.jpg-250.jpg)
ABclonal Technology [KO Validated] ANXA1 Rabbit pAb
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors.