Goat Secondary Antibodies
ABclonal Technology PPP4C Rabbit pAb
Enables protein serine/threonine phosphatase activity. Involved in regulation of double-strand break repair via homologous recombination. Located in cytosol, nucleoplasm, and plasma membrane.
Apexbio Technology LLC HyperFluor™ 594 Goat Anti-Human IgG (H+L) Antibody 100ul
HyperFluor 594 Goat Anti-Human IgG HplusL Antibody is an affinity-purified secondary antibody that specifically targets human immunoglobulin G (IgG) recognizing both heavy and light chains (H L) Conjugated with the HyperFluor 594 fluorophore it facilitates detection of IgG via fluorescence with excitation at 590 nm and emission at 617 nm Based on these characteristics HyperFluor 594 Goat Anti-Human IgG HplusL Antibody is suitable for applications including immunocytochemistry immunohistochemistry and flow cytometry
ABclonal Technology 594 anti-Human/Monkey CD64
This gene encodes a protein that plays an important role in the immune response This protein is a high-affinity Fc-gamma receptor The gene is one of three related gene family members located on chromosome 1
ABclonal Technology APC anti-Human Nectin-1/CD111
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells The protein is a calcium(2 )-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops a single transmembrane domain (in some isoforms) and a cytoplasmic region This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1 HSV-2) and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells Mutations in this gene cause cleft lip and palate ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL P) Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini
ABclonal Technology 488 anti-Human Megalin/LRP2
The gene encodes low-density lipoprotein-related protein 2 (LRP2) or megalin a multi-ligand endocytic receptor primarily expressed in absorptive epithelial tissues like the kidney This glycoprotein has a large extracellular domain a transmembrane domain and a short cytoplasmic tail It binds various macromolecules such as albumin apolipoproteins B and E and lipoprotein lipase LRP2 is essential for the reuptake of lipoproteins sterols vitamin-binding proteins and hormones It also plays a role in cell signaling interacting with extracellular ligands like parathyroid hormone and sonic hedgehog and cytosolic ligands such as MAP kinase scaffold proteins Phosphorylation of its cytoplasmic domain regulates receptor recycling Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR)
ABclonal Technology Biotin anti- CD161c/NK1.1
Enables identical protein binding activity and signaling receptor activity Acts upstream of or within natural killer cell activation and positive regulation of natural killer cell mediated cytotoxicity Located in external side of plasma membrane Is integral component of plasma membrane Is expressed in thymus primordium Orthologous to human KLRB1 (killer cell lectin like receptor B1)
ABclonal Technology 700 anti-Human/Monkey CD20
This gene encodes a member of the membrane-spanning 4A gene family Members of this nascent protein family are characterized by common structural features and similar intron exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells This family member is localized to 11q12 among a cluster of family members Alternative splicing of this gene results in two transcript variants which encode the same protein
ABclonal Technology 594 anti-Human CD261/TRAIL-R1
The protein encoded by this gene is a member of the TNF-receptor superfamily This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10 TRAIL) and thus transduces cell death signal and induces cell apoptosis Studies with FADD-deficient mice suggested that FADD a death domain containing adaptor protein is required for the apoptosis mediated by this protein
