Mouse Secondary Antibodies
Biotium Human IgG4 (Ig Heavy Constant Gamma 4) (G4m Marker) (IGHG4/1345), CF568 conjugate, 0.1mg/mL
The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Reportedly, a large population of patients with recurrent respiratory tract infection has low IgG4 concentrations. IgG4-related sclerosing disease has been recognized as a systemic disease entity characterized by an elevated serum IgG4 level, sclerosing fibrosis, and diffuse lymphoplasmacytic infiltration with the presence of many IgG4-positive plasma cells. IgG4 is overexpressed in inflammatory pseudotumor (IPT) and under expressed in inflammatory myofibrobl
Biotium Occludin (OCLN) (Tight Junctions Marker)(OCLN/2183), CF488A conjugate, 0.1mg/mL
Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of Occludin. Expression of Occludin is upregulated by polyunsaturated fatty acids, increasing trans-endothelial cell resistance and reducing cellular permeability to large molecules. The level of Occludin varies greatly depending on tissue; in brain tissue, Occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial Occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Co
American Research Products Inc Mouse Disintegrin and metallop
Mouse Disintegrin and metalloproteinase domain-containing protein 33 (ADAM33) ELISA kit from CUSABIO Detection Range 15 6 pg/mL-1000 pg/mL Sensitivity 3 9 pg/mL Sample serum plasma tissue homogenates Method Sandwich
American Research Products Inc Mouse Beta Endorphin b EP ELI
Mouse Beta-Endorphin b-EP ELISA Kit from CUSABIO Detection Range 0 78 pg/mL-50 pg/mL Sensitivity 0 195 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Genscript Corporation CTLA-4 Fc Chimera Mouse
CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 is an Inhibitory receptor acting as a major negative regulator of T-cell responses CTLA-4 is a member of the immunoglobulin superfamily which is expressed on the surface of T cells and transmits an inhibitory signal to T cells CTLA-4 and CD28 are homologous receptors expressed by both CD4 and CD8 T cells which mediate opposing functions in T-cell activation Both receptors share a pair of ligands expressed on the surface of antigen-presenting cells (APCs) The affinity of CTLA-4 for its natural B7 family ligands CD80 and CD86 is considerably stronger than the affinity of their cognate stimulatory co-receptor CD28
Cayman Chemical a-HelIcal CRF9-41trIfluo 10mg
A synthetic peptide CRF antagonist; inhibits CRF-induced ACTH release from isolated rat anterior pituitary cells from 0.5-5 µM; inhibits CRF-induced ACTH release in non-anesthetized, intact rats from 0.02-0.6 µmol/kg; inhibits stress-induced ACTH release in rats at 0.6 µmol/kg; increases social interaction time in a rat model of nicotine-induced conditioned anxiety; reduces binge-like ethanol consumption in mice
Cayman Chemical AvIlamycIn A 50mg
An antibiotic; active against veterinary isolates of C. perfringens (MICs = ≤0.06-0.5 mg/L) and B. hyodysenteriae (MICs = 12.5-100 μg/ml); dietary administration reduces mortality in a broiler cockerel model of C. perfringens infection at 15 and 30 ppm
Revvity Health Sciences Inc HTRF Human Total MLKL Detection Kit, 10,000 Assay Points
HTRF Human Total MLKL Detection Kit, 10,000 Assay Points
ABclonal Technology APC Mouse anti-Human CD1a mAb
This gene encodes a member of the CD1 family of transmembrane glycoproteins which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells The human genome contains five CD1 family genes organized in a cluster on chromosome 1 The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system Alternative splicing results in multiple transcript variants
Cayman Chemical CamelInIn A 10mg
A flavonoid with diverse biological activities; inhibits ACE by 30.16% at 500 UG/ml; induces cell cycle arrest at the G1 phase and apoptosis in HepG2 and MCF-7 cells at 200 µM; reduces hepatocyte apoptosis, as well as hepatic TNF-α, IL-6, IL-1β, and MDA levels, in a mouse model of carbon tetrachloride-induced liver injury at 30 mg/kg
Biotang Inc Geminin, Mouse Anti Human, GMNN Antibody, Mouse Anti Human Monoclonal.
Geminin, Mouse Anti Human, GMNN Antibody, Mouse Anti Human Monoclonal.
Biotang Inc Hexokinase-3, Mouse Anti Human, HK3 Antibody,Mouse Anti Human Monoclonal.
Hexokinase-3, Mouse Anti Human, HK3 Antibody,Mouse Anti Human Monoclonal.
Biotium Collagen VII(LH7.2), CF488A conjugate, 0.1mg/mL
Recognizes an epitope located on collagenase digested Type VII collagen (150 kDa), i. e. the non-helical carboxyl terminal region of the dimer. Binding is localized at the inferior border of the lamina densa as demonstrated by immunoelectron microscopy. Type VII is also found in the retina, where its function is unknown. It interacts with Laminin 5 and Fibronectin. Collagen VII is a stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specifi
Biotium Topoisomerase II alpha (Proliferation & Drug-Resistance Marker) (TOP2A/1362), Biotin conjugate, 0.1mg/mL
This antibody recognizes a 170 kDa protein, which is identified as topoisomerase IIα. It shows no cross-reaction with topoisomerase IIβ or topoisomerase I. Topo IIα plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIα is also implicated in drug resistance of tumor cells.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.