Rabbit Secondary Antibodies
Cayman Chemical AMACRNTerm RabbIt Monclo 100uL
A heterocyclic building block has been used in the synthesis of prolyl-tRNA synthase inhibitors
ABclonal Technology ARFRP1 / ARP Rabbit mAb
The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes Alternatively spliced transcript variants encoding different isoforms have been identified
ABclonal Technology OXGR1 / GPR99 Rabbit mAb
This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily The encoded protein is activated by the citric acid intermediate oxoglutarate as well as several cysteinyl leukotrienes including leukotrienes E4 C4 and D4 which are implicated in many inflammatory disorders In mice a knock-out of this gene leads to middle ear inflammation changes in the mucosal epithelium and an increase in fluid behind the eardrum and is associated with hearing loss Alternative splicing results in multiple transcript variants
ABclonal Technology ALDH7A1 Rabbit mAb
The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation This particular member has homology to a previously described protein from the green garden pea the 26g pea turgor protein It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix Recent reports show that this protein is found both in the cytosol and the mitochondria and the two forms likely arise from the use of alternative translation initiation sites An additional variant encoding a different isoform has also been found for this gene Mutations in this gene are associated with pyridoxine-dependent epilepsy Several related pseudogenes have also been identified
Cayman Chemical LFA3CD58 RabbIt Monclonal 50uL
An inhibitor of RNA polymerase I-mediated transcription binds to G-quadruplex DNA and inhibits the interaction between ribosomal DNA G-quadruplexes and nucleolin induces nucleolin mislocalization from the nucleoli to the nucleoplasm in A549 cells at 10 UM induces apoptosis in A549 and HL-60 cells at 5 UM reduces tumor growth in MDA-MB-231 and MiaPaCa-2 mouse xenograft models at 5 mg/kg
