Rabbit Secondary Antibodies
ABclonal Technology PE Rabbit anti-Mouse CD87 mAb
Predicted to enable enzyme binding activity protein domain specific binding activity and signaling receptor binding activity Predicted to be involved in several processes including negative regulation of apoptotic signaling pathway positive regulation of epidermal growth factor receptor signaling pathway and positive regulation of release of cytochrome c from mitochondria Is integral component of plasma membrane Is expressed in several structures including decidua early conceptus and spleen Human ortholog(s) of this gene implicated in rheumatoid arthritis Orthologous to human PLAUR (plasminogen activator urokinase receptor)
ABclonal Technology APC Rabbit anti-Mouse IgG1 mAb
Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response Mouse IgG1 is composed of two heavy chains and two light chains and it is involved in opsonization complement activation and antibody-dependent cell-mediated cytotoxicity It is also involved in the regulation of immune responses including the activation of T cells and the inhibition of B cell activation Mouse IgG1 is widely used in research and diagnostic applications including ELISA Western blotting and immunohistochemistry It is also used in therapeutic applications such as immunotherapy and vaccine development
ABclonal Technology APC Rabbit anti-Mouse CD22 mAb
Enables CD4 receptor binding activity protein phosphatase binding activity and sialic acid binding activity Involved in several processes including negative regulation of calcium-mediated signaling negative regulation of immunoglobulin production and regulation of B cell proliferation Located in external side of plasma membrane and neuronal cell body membrane Is integral component of plasma membrane Is expressed in several structures including alimentary system brain hemolymphoid system gland liver and biliary system and reproductive system Orthologous to human CD22 (CD22 molecule)
ABclonal Technology APC Rabbit anti-Mouse CD11b
Enables complement component C3b binding activity heparan sulfate proteoglycan binding activity and heparin binding activity Contributes to cargo receptor activity Involved in several processes including central nervous system development endocytosis and positive regulation of neuron death Acts upstream of or within several processes including activated T cell proliferation leukocyte migration and microglia development Located in external side of plasma membrane and nucleus Is integral component of membrane Part of integrin alphaM-beta2 complex Is expressed in several structures including central nervous system heart lymphatic vessel thymus and yolk sac Human ortholog(s) of this gene implicated in lupus nephritis Orthologous to human ITGAM (integrin subunit alpha M)
ABclonal Technology PE Rabbit anti-Mouse CD68 mAb
Involved in several processes including cellular response to lipopolysaccharide cellular response to oxidised low-density lipoprotein particle stimulus and negative regulation of dendritic cell antigen processing and presentation Acts upstream of or within aging and cellular response to organic substance Located in lysosome and plasma membrane Is expressed in several structures including central nervous system embryo mesenchyme heart blood vessel liver and spleen Orthologous to human CD68 (CD68 molecule)
ABclonal Technology APC Rabbit anti-Mouse CD93 mAb
Predicted to enable complement component C1q complex binding activity Predicted to be involved in cell-cell adhesion Predicted to act upstream of or within cell adhesion Located in cell surface cytoplasmic vesicle and plasma membrane Is expressed in blood vessel Orthologous to human CD93 (CD93 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD6 mAb
Predicted to enable several functions including identical protein binding activity lipopolysaccharide binding activity and lipoteichoic acid binding activity Predicted to be involved in several processes including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules lipopolysaccharide-mediated signaling pathway and positive regulation of macromolecule metabolic process Predicted to act upstream of or within cell adhesion Predicted to be located in immunological synapse Predicted to be spanning component of plasma membrane Predicted to be part of T cell receptor complex Predicted to be active in external side of plasma membrane Orthologous to human CD6 (CD6 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD56/NCAM
Predicted to enable LRR domain binding activity and phosphatase binding activity Involved in commissural neuron axon guidance and regulation of semaphorin-plexin signaling pathway Acts upstream of or within several processes including homotypic cell-cell adhesion positive regulation of calcium-mediated signaling and regulation of exocyst assembly Located in several cellular components including external side of plasma membrane growth cone and neuronal cell body Is expressed in several structures including embryo mesenchyme nervous system sensory organ skin and urinary system Human ortholog(s) of this gene implicated in bipolar disorder middle cerebral artery infarction and pancreatic cancer Orthologous to human NCAM1 (neural cell adhesion molecule 1)
ABclonal Technology PE Rabbit anti-Mouse CD44 mAb
This gene enables hyaluronic acid and type II TGF-beta receptor binding contributing to cytokine binding and receptor activity It regulates T cell activation protein phosphorylation and intracellular signaling Involved in Wnt signaling epithelium morphogenesis and wound healing it plays a role in inflammatory response Located in the basolateral plasma membrane external plasma membrane and microvilli it is part of the macrophage migration inhibitory factor receptor complex Expressed in various systems including alimentary branchial arch CNS genitourinary and limb Human orthologs are linked to breast carcinoma multiple carcinomas and prostate cancer It is orthologous to human CD44 a molecule in the Indian blood group
ABclonal Technology 594 Rabbit anti-Human CD98
This gene is a member of the solute carrier family and encodes a cell surface transmembrane protein The protein exists as the heavy chain of a heterodimer covalently bound through di-sulfide bonds to one of several possible light chains The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids Alternatively spliced transcript variants encoding different isoforms have been characterized
ABclonal Technology 488 Rabbit anti-Human CD40
This gene is a member of the TNF-receptor superfamily and encodes a receptor on antigen-presenting cells essential for immune and inflammatory responses including T cell-dependent immunoglobulin class switching memory B cell development and germinal center formation The AT-hook transcription factor AKNA regulates this receptor and its ligand playing a role in homotypic cell interactions The receptor s interaction with its ligand is vital for amyloid-beta-induced microglial activation an early event in Alzheimer s disease Mutations in this gene cause autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3) Multiple alternatively spliced variants encoding distinct isoforms have been reported