Rabbit Secondary Antibodies
Cayman Chemical PLAPNTerm RabbIt Monclon 100uL
An inhibitor of SIK2 (IC50 50s 21.63 and 6.63 nM respectively) inhibits TNF-a secretion in RAW 264.7 cells (IC50 ~2.5 UM) and reduces phosphorylation of CRTC3 and HDAC4 in macrophages at 3 UM inhibits growth of 10 ovarian cancer cell lines (IC50s 0.8-2.6 UM) and increases sensitivity of eight of them to paclitaxel halts the cell cycle at the G2/M phase and induces apoptosis and tetraploidy in SKOV3 cells at 1 UM has an additive effect on reducing tumor growth when used in combination with paclitaxel in an ovarian cancer mouse xenograft model at 60 mg/kg per day
ABclonal Technology CD105/Endoglin Rabbit mAb
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity Mutations in this gene cause hereditary hemorrhagic telangiectasia also known as Osler-Rendu-Weber syndrome 1 an autosomal dominant multisystemic vascular dysplasia This gene may also be involved in preeclampsia and several types of cancer Alternatively spliced transcript variants encoding different isoforms have been found for this gene
Cayman Chemical CD79aCTerm RabbIt Monclo 100uL
A BET family protein inhibitor inhibits binding of BRD2 BRD3 and BRD4 to an acetylated histone H4 peptide in vitro decreases Myc levels in and inhibits proliferation of AML DLBCL and MM cells reduces tumor growth in AML DLBCL and MM mouse xenograft models reduces tumor growth when administered alone or in combination with docetaxel or MDV 3100 in a 22Rv1 CRPC mouse xenograft model
ABclonal Technology H2-Ab1 Rabbit mAb
Enables several functions including peptide antigen binding activity protein antigen binding activity and toxic substance binding activity Involved in several processes including B cell affinity maturation cellular response to interferon-gamma and positive regulation of T-helper 1 type immune response Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and immune response Located in Golgi apparatus endosome and external side of plasma membrane Is integral component of membrane Part of MHC class II protein complex Is expressed in lung metanephros and thymus primordium Orthologous to human HLA-DQB2 (major histocompatibility complex class II DQ beta 2)
ABclonal Technology WFS1 Rabbit mAb
This gene encodes a transmembrane protein which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain pancreas heart and insulinoma beta-cell lines Mutations in this gene are associated with Wolfram syndrome also called DIDMOAD (Diabetes Insipidus Diabetes Mellitus Optic Atrophy and Deafness) an autosomal recessive disorder The disease affects the brain and central nervous system Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6) also known as DFNA14 or DFNA38 Alternatively spliced transcript variants have been found for this gene
Abcam Rabbit Anti Rat Igg Hl Hrp AB102172-1MG
Rabbit Anti Rat Igg Hl Hrp AB102172-1MG
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology APC Rabbit anti-Mouse CD93 mAb
Predicted to enable complement component C1q complex binding activity Predicted to be involved in cell-cell adhesion Predicted to act upstream of or within cell adhesion Located in cell surface cytoplasmic vesicle and plasma membrane Is expressed in blood vessel Orthologous to human CD93 (CD93 molecule)
ABclonal Technology ABflo 488 Rabbit anti- IgG1
Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response Mouse IgG1 is composed of two heavy chains and two light chains and it is involved in opsonization complement activation and antibody-dependent cell-mediated cytotoxicity It is also involved in the regulation of immune responses including the activation of T cells and the inhibition of B cell activation Mouse IgG1 is widely used in research and diagnostic applications including ELISA Western blotting and immunohistochemistry It is also used in therapeutic applications such as immunotherapy and vaccine development
Jackson Immuno Research Labs AFFINIPURE F 1MG
AffiniPure Rabbit Anti-Goat IgG, F(ab')2 Fragment Specific (min X Hu Sr Prot)
Jackson Immuno Research Labs Fluorescein (FITC)-AffiniPure F(ab')2 Fragment Rabbit Anti-Goat IgG Fc Fragment Specific
Fluorescein (FITC)-AffiniPure F(ab')2 Fragment Rabbit Anti-Goat IgG Fc Fragment Specific
Jackson Immuno Research Labs Alexa Fluor 594-AffiniPure F(ab')2 Fragment Rabbit Anti-Goat IgG F(ab')2 Fragment Specific
Alexa Fluor 594-AffiniPure F(ab')2 Fragment Rabbit Anti-Goat IgG F(ab')2 Fragment Specific