Rat Secondary Antibodies
Genscript Corporation CD40/TNFRSF5 His Rat
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects CD40 molecule is a potential target for cancer immunotherapy There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells
Genscript Corporation Human Lambda Light Chain 2D54
Immunoglobulins (Ig) and free light chains (FLC) is involved in humoral immune response Ig is composed of two identical light chains and two identical heavy chains FLC contains two types kappa free light chain (KFLC) and lambda free light chain (LFLC) The expression of Kappa or Lambda is greatly increased in multiple myeloma or other B cell malignancies It is useful for the identification of certain non-Hodgkin s lymphomas leukemias and plasmacytomas Immunohistochemistry is commonly applied for the detection of free light chains
ABclonal Technology 488 Rabbit anti- CD162/PSGL-1
Involved in leukocyte adhesive activation Acts upstream of or within leukocyte tethering or rolling Predicted to be located in plasma membrane raft and uropod Predicted to be active in plasma membrane Is expressed in brain and thymus primordium Human ortholog(s) of this gene implicated in carotid artery disease Orthologous to human SELPLG (selectin P ligand)
ABclonal Technology APC anti-Human CD162/PSGL-1
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P- E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes As such this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins This protein requires two post-translational modifications tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans for its high-affinity binding activity Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response Alternate splicing results in multiple transcript variants
ABclonal Technology APC anti-Human CD162/PSGL-1
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P- E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes As such this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins This protein requires two post-translational modifications tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans for its high-affinity binding activity Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response Alternate splicing results in multiple transcript variants
ABclonal Technology 700 Rabbit anti- CD162/PSGL-1
Involved in leukocyte adhesive activation Acts upstream of or within leukocyte tethering or rolling Predicted to be located in plasma membrane raft and uropod Predicted to be active in plasma membrane Is expressed in brain and thymus primordium Human ortholog(s) of this gene implicated in carotid artery disease Orthologous to human SELPLG (selectin P ligand)
MOLECULAR DEPOT LLC Lambda FLC Antibody - 1 mg
Lambda Free Light Chains Antibody (1 mg) consists of affinity-purified polyclonal antibodies specific to human Lambda Free Light Chains Tested in several immunoassay platforms including ELISA CLIA Immunoturbidimetry and more Readily available in bulk amounts and at bulk prices Biotinylation and other labeling services are also available For in vitro research use only
ABclonal Technology PE/Cyanine7 anti-h CD90/Thy1
This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins The encoded protein is involved in cell adhesion and cell communication in numerous cell types but particularly in cells of the immune and nervous systems The encoded protein is widely used as a marker for hematopoietic stem cells This gene may function as a tumor suppressor in nasopharyngeal carcinoma Alternative splicing results in multiple transcript variants
ABclonal Technology PE/Cy7 anti- Ly-6A/E Sca-1
Predicted to enable acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity Acts upstream of or within response to bacterium Located in external side of plasma membrane Is expressed in alimentary system hindlimb tendon liver metanephros and physiological umbilical hernia Used to study osteoporosis Orthologous to human LY6H (lymphocyte antigen 6 family member H)
ABclonal Technology APC anti-Human CD90/Thy1
This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins The encoded protein is involved in cell adhesion and cell communication in numerous cell types but particularly in cells of the immune and nervous systems The encoded protein is widely used as a marker for hematopoietic stem cells This gene may function as a tumor suppressor in nasopharyngeal carcinoma Alternative splicing results in multiple transcript variants
ABclonal Technology PE Rabbit anti- CD162/PSGL-1
Involved in leukocyte adhesive activation Acts upstream of or within leukocyte tethering or rolling Predicted to be located in plasma membrane raft and uropod Predicted to be active in plasma membrane Is expressed in brain and thymus primordium Human ortholog(s) of this gene implicated in carotid artery disease Orthologous to human SELPLG (selectin P ligand)