DMT-2′Fluoro-dU Phosphoramidite is a uridine phosphoramidite featuring a fluorine atom at the 2' position. This compound is suitable for nucleoside modification and the synthesis of DNA. Fluorination, a prevalent chemical derivatization in pharmaceutical chemistry, leverages fluorine's unique biophysical and biochemical properties, including its small size and high electronegativity. The ongoing research and development of novel fluorinated nucleic acid molecules are crucial for advancements in drug discovery and fundamental biochemical studies.
- Uridine phosphoramidite with fluorine at the 2' position
- Can be used for nucleoside modification
- Suitable for synthesis of DNA
- Supports innovative drug discovery
- Aids basic biochemical studies