Apoptosis Reagents and Kits
ABclonal Technology Caspase-1 Rabbit pAb
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
Apexbio Technology LLC Annexin V-PE/DAPI Apoptosis Kit 200tests
Annexin V-PE/DAPI Apoptosis Kit enables differentiation between early apoptotic late apoptotic and dead cells Annexin V is a Ca2 -dependent phospholipid-binding protein that specifically binds to phosphatidylserine (PS) PS is normally located on the inner leaflet of the cell membrane phospholipid bilayer However during the early stages of apoptosis PS moves from the inner surface to the outer surface of the cell membrane becoming exposed to the extracellular environment Labeled with a fluorescence dye such as PE Annexcin V is commonly used as a fluorescent probe to detect apoptosis through flow cytometry or fluorescence microscopy within 15-30 minutes Additionally this kit includes the nuclear stain DAPI which specifically binds to double-stranded DNA to emit blue fluorescence Normally DAPI cannot penetrate intact cell membranes In late apoptotic and dead cells DAPI can cross the compromised membrane to stain the nucleus
Selleck Chemical LLC A-1155463 5mg 1235034-55-5
A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W(Ki=19 nM) and MCL-1(Ki>440 nM). *For Research & Development use only. Product is not intended for drug, household, or human consumption.
ABclonal Technology Annexin A4/Annexin IV Rabbit pAb
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene.
Abcam Human RICTOR knockout A549 cell lysate.
Human RICTOR knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human Lgals9 (galectin 9/Gal-9) knockout A549 cell lysate.
Human Lgals9 (galectin 9/Gal-9) knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human VAMP8 (EDB) knockout A-431 cell lysate.
Human VAMP8 (EDB) knockout A-431 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Annexin A1/ANXA1 Mo 10ug
Recombinant mouse Annexin A1 (His-tagged) is a full-length protein expressed in E. coli, provided lyophilized and quality-tested for purity and biological activity. It is designed for in vitro biochemical characterization and cell-based assays that require a His-tagged mouse Annexin A1 protein.
- Full-length mouse protein with N-terminal 6xHis tag.
- Expressed in E. coli and >95% pure by reducing SDS-PAGE.
- Lyophilized formulation with trehalose for improved stability.
- Demonstrated biological activity: inhibits TNF-alpha secretion in RAW264.7 cells.
- Stable when stored at -20°C; aliquot and store at -80°C for extended storage.
Bioss KD-Validated Annexin A7 Rabbit
Annexin A7 Primary Antibody Unconjugated Public Immunogen Range 1-150/488 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Abcam Human VDR (Vitamin D Receptor) knockout HeLa cell lysate.
Human VDR (Vitamin D Receptor) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human L3MBTL3 knockout HEK-293T cell lysate.
Human L3MBTL3 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human CD44 knockout HeLa cell lysate.
Human CD44 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human TUBB3 (beta III Tubulin) knockout HeLa cell lysate.
Human TUBB3 (beta III Tubulin) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human RBPMS knockout HeLa cell lysate.
Human RBPMS knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PPID (Cyclophilin 40) knockout HeLa cell lysate.
Human PPID (Cyclophilin 40) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement