Apoptosis Reagents and Kits
Creative Biomart TNF-Related Apoptosis-Inducing Ligand (TRAIL)
TRAIL/APO 2 Ligand Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 168 amino acids (Met+Arg115-Gly281) and having a molecular mass of ~21kDa. The sTRAIL is purified by proprietary chromatographic techniques.
Cayman Chemical Z-YVAD-AFC (trifluoroacetate salt), Purity: ≥95%, 1 mg
A fluorogenic substrate for caspase-1; AFC is released upon enzymatic cleavage by caspase-1 and its fluorescence can be used to quantify caspase-1 activity; ex/em = 400/505 nm, respectively
Apexbio Technology LLC Annexin V-APC/DAPI Apoptosis Kit 20tests
Annexin V-APC/DAPI Apoptosis Kit allow discrimination between cells at various stages of apoptosis and cell death Annexin V is a calcium-dependent phospholipid-binding protein which specifically binds to phosphatidylserine (PS) Under normal conditions PS is located on the inner surface of the cell membrane lipid bilayer but during early apoptosis PS translocates from the inner leaflet to the outer leaflet of the plasma membrane becoming exposed to the extracellular environment By using Annexin V-APC labeling apoptotic cells can be detected easily through flow cytometry or fluorescence microscopy within 15-30 minutes Additionally this kit includes the nuclear stain DAPI which specifically binds to double-stranded DNA to emit blue fluorescence Normally DAPI cannot penetrate intact cell membranes In late apoptotic and dead cells DAPI can cross the compromised membrane to stain the nucleus
Abcam Human PPP1CC (PP1C gamma) knockout HeLa cell lysate.
Human PPP1CC (PP1C gamma) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
CPC Scientific Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO 0.5MG
ONE-LETTER SEQUENCE: Ac-AAVALLPAVLLALLAPDEVD-CHOMOLECULAR FORMULA: C94H158N20O27MOLECULAR WEIGHT:2000.4STORAGE CONDITIONS: -20 5CRESEARCH AREA: ApoptosisREFERENCES: Y.Z. Lin et al., J. Biol. Chem., 271, 5305 (1996); D.W. Nicholson, Nature Biotechnol., 14, 297 (1996); M. Tewari et al., Cell, 81, 801 (1995)
AdipoGen b-AP15
Chemical. CAS 1009817-63-3. Formula C22H17N3O6. MW 419.4. b-AP15 is a specific deubiquitinase DUB inhibitor. It inhibits ubiquitin-specific-processing protease 14 USP14 and ubiquitin c-terminal hydrolase isozyme L5 UCHL5 UCH37, two 19S regulatory particle proteasome-associated DUBs. It exhibits minimal inhibition of UCHL-1, UCHL-3, USP2, USP7, USP and BAP1. Has been described to inhibit also the 20S proteasome with an IC50 comparable to that required for inhibiting the 19S regulatory particles. b-AP15 has anticancer properties and blocks tumor progression in vivo in mice and prevents organ infiltration in mouse models of myeloid leukemia. b-AP15 also renders tumor cells sensitive to TNF-mediated apoptosis by natural killer and T cells. It induces apoptosis, ER stress and autophagy in several cancer cells. b-AP15 has anti-inflammatory properties inhibiting ERK1/2 and JNK phosphorylation, increasing IkappaBalpha levels and inhibiting NF-kappaB p65.
Cell Signaling Technology PathScanR RP Cleaved Caspase-9 Asp315 Sandwich ELISA Kit 20 Kit
PathScanR RP Cleaved Caspase-9 Asp315 Sandwich ELISA Kit 20 Kit
Abcam Human STK24 knockout A-431 cell lysate.
Human STK24 knockout A-431 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Kinetic Apoptosis Kit (Microscopy)
Kinetic Apoptosis Kit (Microscopy)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human Lipoprotein A Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human Lipoprotein A Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human Lipoprotein A.
The product is subject to the following: Abcam Restricted Use Statement