Apoptosis Reagents and Kits
Abcam Human IGF1R (IGF1 Receptor) knockout HeLa cell lysate.
Human IGF1R (IGF1 Receptor) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PLXNB2 (Plexin B2/MM1) knockout HEK-293 cell lysate.
Human PLXNB2 (Plexin B2/MM1) knockout HEK-293 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Enzo Life Sciences Ac-WEHD-AMC (1mg)
Substrate for caspase-1, -4 and -5. Fluorogenic substrate for caspase-1 (Km=4µM), -4 (Km=31µM);and -5 (Km=15µM). This fluorogenic caspase-1 substrate with an optimal tetrapeptide sequence is cleaved 50-fold more efficiently than Ac-YVAD-AMC (ALX-260-024). Alternative name: Caspase 1 substrate (fluorogenic), Caspase 5 substrate (fluorogenic), Caspase 4 substrate (fluorogenic). Formula: C38H40N8O11. MW: 784.8. Purity: ≥98% (HPLC). Formulation: Lyophilized. Peptide content: 70-90%. Solubility: Soluble in DMSO (100mM, 75.5mg/ml). Dilute with distilled water or buffer. Long Term Storage: -20°C. Handling: Protect from light and moisture.
Abcam Annexin V-iFluor 555 Apoptosis Staining / Detection Reagent.
Annexin V-iFluor 555 Apoptosis Staining / Detection Reagent.
The product is subject to the following: Abcam Restricted Use Statement
Abcam MMP2 Inhibitor Screening Assay Kit (Fluorometric).
MMP2 Inhibitor Screening Assay Kit (Fluorometric).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human TPM4 knockout HEK-293T cell lysate.
Human TPM4 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human FYN knockout HEK-293 cell lysate.
Human FYN knockout HEK-293 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Meso Scale Discovery R-PLEX Human Caspase-1 ASYQP
The R-Plex Human Caspase-1 Assay Kit from Meso Scale Discovery is used to quantitatively measure caspase-1 in human biological samples such as serum plasma cell culture supernatants and cell lysates The assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity a broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an ECL tag and calibrator diluent The assay takes approximately 3 5 hours to complete after a 2 hour incubation period The kit can perform up to 94 assays in the 96-well plate format
Abcam Human COL6A1 knockout HEK-293T cell lysate.
Human COL6A1 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human TGM2 (Transglutaminase 2) knockout A549 cell lysate.
Human TGM2 (Transglutaminase 2) knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human CNP (CNPase) knockout HeLa cell lysate.
Human CNP (CNPase) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen RBN-2397
Chemical. CAS 2381037-82-5. Formula C20H23F6N7O3. MW 523.4. RBN-2397 is a potent NAD competitive small molecule inhibitor of PARP-7. RBN-2397 selectively inhibits PARP-7 and demonstrates >50-fold selectivity for inhibition of PARP-7 over all PARP family members as measured by biochemical assays. RBN-2397 inhibits PARP-7-dependent MARylation IC50 = 2nM in cell biochemical assay and inhibits cells proliferation in NCI-H1373 lung cancer cells IC50 = 20nM. By selectively inhibiting PARP-7 in tumor cells, RBN-2397 has been shown to directly inhibit cellular proliferation and restore Type I interferon signaling to stimulate an innate and adaptive antitumor immune response. Targeting cytosolic nucleic acid sensing pathways and the Type I interferon IFN response is an emerging therapeutic strategy being explored in oncology. The PARP family consists of seventeen enzymes that regulate fundamental biological processes including response to cellular stress.
Abcam Human ABCC1 (MRP1) knockout HeLa cell lysate.
Human ABCC1 (MRP1) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human FGF21 knockout HeLa cell lysate.
Human FGF21 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human TSPO (PBR) knockout HeLa cell lysate.
Human TSPO (PBR) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement