Apoptosis Reagents and Kits
Abcam Human COPS7B (CSN7b) knockout HEK-293T cell lysate.
Human COPS7B (CSN7b) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human MALT1 (MLT) knockout HeLa cell lysate.
Human MALT1 (MLT) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human CTTN (Cortactin) knockout HEK-293T cell lysate.
Human CTTN (Cortactin) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human CTSH (Cathepsin H) knockout HEK-293T cell lysate.
Human CTSH (Cathepsin H) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Annexin V CF Blue 7 AAD Apoptosis Staining Detection Kit
Annexin V CF Blue 7 AAD Apoptosis Staining Detection Kit
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx KILR WIL2-S (Human) Cytotoxicity Assay Kit (cell pool)
The KILR WIL2-S (Human) Stable Cell Pool Cytotoxicity Assay utilizes the engineered stable target cell pool that is used to measure direct death mediated by immuno-oncology treatments via ADCC, CDC, and ADCP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Abcam Human NUDT1 (MTH1) knockout HEK-293T cell lysate.
Human NUDT1 (MTH1) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Ac-AAVALLPAVLLALLAP-IETD-CHO (trifluoroacetate salt), Purity: ≥95%, 1 mg
A composite of a caspase-8 inhibitor and a cell-permeable hydrophobic sequence; an inhibitor of caspase-8 and granzyme B; prevents death of SKOV3 ovarian carcinoma cells transfected with SAGA at 20 µM
Abcam Human NMI (N myc interactor/NMI) knockout A549 cell lysate.
Human NMI (N myc interactor/NMI) knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human CLDN1 knockout A-431 cell lysate.
Human CLDN1 knockout A-431 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human YWHAG (14-3-3 gamma) knockout HEK-293T cell lysate.
Human YWHAG (14-3-3 gamma) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Caspase-3/7 Inhibitor I, Purity: ≥98%, CAS: 1110670-49-9, 5 mg
A potent, reversible, and highly selective isatin sulfonamide-based inhibitor of caspase-3 (Ki(app) = 60 nM; IC50 = 120 nM) and caspase-7 (Ki(app) = 170 nM); inhibits apoptosis in camptothecin treated Jurkat cells (IC50 = ~50 µM) and in chondrocytes (44% inhibition at 10 µM and 98% inhibition at 50 µM)
Abcam Human PODXL knockout HCT116 cell lysate.
Human PODXL knockout HCT116 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human ENG (CD105) knockout HeLa cell lysate.
Human ENG (CD105) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Caspase-1 Rabbit pAb
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.