Neuroscience Reagents and Kits
Cayman Chemical tetrnorPGDM AChE Tracer 100dtn
An IRF3 activator and adjuvant increases the mRNA expression of the genes encoding ISG54 and OASL in PH5CH8 cells and increases CXCL10 production in phorbol 12-myristate 13-acetate-differentiated THP-1 monocytes at 10 UM immunization with a vaccine in combination with KIN1148 increases blood IgG neutralizing and hemagglutinin antibody titers decreases PFUs in the lungs and lung-draining lymph nodes and increases the survival percentage of mice infected with a lethal dose of influenza virus when used as an adjuvant
Cayman Chemical CyclIc AMP AChE Tracer 500dtn
A steroidal glycoside with diverse biological activities reduces the proliferation of LNCaP and T47D cancer cells (IC50s 32.1 and 27.5 UM respectively) inhibits TNF-a-induced nuclear translocation of NF-KB in HaCaT keratinocytes at 50 nM decreases AST serum levels in a mouse model of carbon tetrachloride-induced liver injury at 0.1 mg/kg topical administration reduces ear epidermal thickness and scaling as well as leukocyte and macrophage infiltration in an imiquimod-induced mouse model of psoriasis at 5 mg/kg
Cell Signaling Technology PathScanR Nestin Sandwich ELISA Kit 10 Kit
PathScanR Nestin Sandwich ELISA Kit 10 Kit
American Research Products Inc Rat glial cell line deriVed ne
Rat glial cell line-deriVed neurotrophic factor GDNF ELISA KIT from CUSABIO Detection Range 31 25 pg/mL-2000 pg/mL Sensitivity 7 81 pg/mL Sample serum plasma cell culture supernates Method Sandwich
Cayman Chemical 8-Isoprostn AChE Tracer 100dtn
A cardiac glycoside with cardiotonic and antiarrhythmic activities inhibits Na /K -ATPase in an isoform-specific biphasic manner with IC50 values of 0.298 and 410 UM for the high- and low affinity human erythrocyte isoenzymes respectively and 1.18 and 28.5 UM for the high- and low affinity porcine cerebral cortex isoenzymes respectively increases contractility and rhythmicity in isolated guinea pig heart in a concentration-dependent manner a degradation product of digoxin
Cayman Chemical EstradIol AChE Tracer 500dtn
An inhibitor of deubiquitinating enzymes inhibits UCH-L1 UCH-L3 and USP8 in a cell-free assay at 10 UM as well as USP5 in a reporter assay at the same concentration inhibits the 26S proteasome but not the 20S proteasome in a reporter assay using HeLa cancer cells at 10 UM increases the levels of polyubiquitinated proteins in HeLa and TOV21G1 cancer cells at 5 UM induces cell cycle arrest at the S and G2/M phases in HeLa cells at 10 UM decreases the viability of nine cancer cell lines (IC50s 1.64-12.49 UM) increases survival and decreases tumor and ascitic fluid mass in an ES-2 ovarian cancer mouse xenograft model at 5 mg/kg every other day
Cell Signaling Technology PathScanR Nestin Sandwich ELISA Kit 20 Kit
PathScanR Nestin Sandwich ELISA Kit 20 Kit