Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Potent and selective serotonin uptake inhibitor. Clinically useful antidepressant. Purity: ≥98% (UHPLC). Solubility: Soluble in water (4mg/ml). Long Term Storage: Ambient.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A glucocorticoid receptor agonist and an active metabolite of beclomethasone dipropionate binds to the glucocorticoid receptor (IC50 3 nM) inhibits PMA-induced glucocorticoid receptor transrepression as well as induces transactivation of the glucocorticoid receptor in CV-1 cells expressing the human receptor inhibits LPS-induced increases in IL-6 IL-8 and TNF-a levels in primary human lung macrophages from patients with COPD (IC50s 0.36 2.04 and 0.21 nM respectively)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A steroidal glycoside with diverse biological activities reduces the proliferation of LNCaP and T47D cancer cells (IC50s 32.1 and 27.5 UM respectively) inhibits TNF-a-induced nuclear translocation of NF-KB in HaCaT keratinocytes at 50 nM decreases AST serum levels in a mouse model of carbon tetrachloride-induced liver injury at 0.1 mg/kg topical administration reduces ear epidermal thickness and scaling as well as leukocyte and macrophage infiltration in an imiquimod-induced mouse model of psoriasis at 5 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Nestin is intermediate dilament protein and belongs to a class VI intermediate filament The protein is commonly known neural stem cells and neural progenitor cells marker in developmen of the central nervous system This antibody specifically recognizes mouse Nestin
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An inhibitor of deubiquitinating enzymes inhibits UCH-L1 UCH-L3 and USP8 in a cell-free assay at 10 UM as well as USP5 in a reporter assay at the same concentration inhibits the 26S proteasome but not the 20S proteasome in a reporter assay using HeLa cancer cells at 10 UM increases the levels of polyubiquitinated proteins in HeLa and TOV21G1 cancer cells at 5 UM induces cell cycle arrest at the S and G2/M phases in HeLa cells at 10 UM decreases the viability of nine cancer cell lines (IC50s 1.64-12.49 UM) increases survival and decreases tumor and ascitic fluid mass in an ES-2 ovarian cancer mouse xenograft model at 5 mg/kg every other day
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions{2227} and shown to be produced by Cu2 -catalyzed oxidation of LDL.{2228} Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate a major component of LDL to 13-HODE cholesteryl ester.{11262412}
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More