NOS inhibitor. Competitively inhibits the generation of NO from arginine and is a useful tool for inhibition of NO mediated effects. In vitro, L-NMMA inhibits relaxation of rat aorta rings induced by acetylcholine (IC50=9.5µM). In vivo, it causes a dose dependent increase in mean arterial blood pressure in anesthetized rats (EC50=16.7mg/kg). Alternative name: NG-Monomethyl-L-arginine . monoacetate. Formula: C7H16N4O2 . CH3COOH. MW: 188.2 . 60.1. Purity: ≥99% (TLC). Appearance: White to off-white solid. Solubility: Soluble in water, 100% ethanol (1mg/ml) or DMSO (0.25mg/ml). Long Term Storage: +4°C.