Signal Transduction Reagents and Kits

Kits, assays, systems, reagents, inhibitors, and a variety of other products for use in the study of cellular signal transduction pathways.

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31 – 45 of 859 results

MilliporeSigma™ Simplicon™ RNA Reprogramming Kit (OKSG)

For use as transfection reagent.

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Thermo Scientific Chemicals Sulindac

CAS: 38194-50-2 Molecular Formula: C₂₀H₁₇FO₃S Synonym: cis-5-Fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]indene-3-acetic acid; MK-231

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Specifications

CAS	38194-50-2
Synonym	cis-5-Fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]indene-3-acetic acid; MK-231
Molecular Formula	C₂₀H₁₇FO₃S

Thermo Scientific Chemicals Adenylyl Cyclase Type V Inhibitor, NKY80

CAS: 299442-43-6 Molecular Formula: C12H11N3O2,C12H11N3O2 Molecular Weight (g/mol): 229.24 InChI Key: SOJUSNIBPPMLCC-UHFFFAOYNA-N Synonym: NKY80; 2-Amino-7-(furan-2-yl)-7,8-dihydroquinazolin-5(6H)-one IUPAC Name: 2-amino-7-(furan-2-yl)-5,6,7,8-tetrahydroquinazolin-5-one SMILES: NC1=NC=C2C(=O)CC(CC2=N1)C1=CC=CO1

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Specifications

CAS	299442-43-6
Molecular Weight (g/mol)	229.24
SMILES	NC1=NC=C2C(=O)CC(CC2=N1)C1=CC=CO1
Synonym	NKY80; 2-Amino-7-(furan-2-yl)-7,8-dihydroquinazolin-5(6H)-one
IUPAC Name	2-amino-7-(furan-2-yl)-5,6,7,8-tetrahydroquinazolin-5-one
InChI Key	SOJUSNIBPPMLCC-UHFFFAOYNA-N
Molecular Formula	C12H11N3O2,C12H11N3O2

Thermo Scientific Chemicals SR-12813, 98%

CAS: 126411-39-0 Molecular Formula: C24H42O7P2,C24H42O7P2 Molecular Weight (g/mol): 504.54 InChI Key: YQLJDECYQDRSBI-UHFFFAOYSA-N Synonym: Tetraethyl 2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethenyl-1,1-bisphosphonate; IUPAC Name: diethyl [2-(3,5-di-tert-butyl-4-hydroxyphenyl)-1-(diethoxyphosphoryl)ethenyl]phosphonate SMILES: CCOP(=O)(OCC)C(=CC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C)P(=O)(OCC)OCC

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Specifications

CAS	126411-39-0
Molecular Weight (g/mol)	504.54
SMILES	CCOP(=O)(OCC)C(=CC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C)P(=O)(OCC)OCC
Synonym	Tetraethyl 2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethenyl-1,1-bisphosphonate;
IUPAC Name	diethyl [2-(3,5-di-tert-butyl-4-hydroxyphenyl)-1-(diethoxyphosphoryl)ethenyl]phosphonate
InChI Key	YQLJDECYQDRSBI-UHFFFAOYSA-N
Molecular Formula	C24H42O7P2,C24H42O7P2

Thermo Scientific Chemicals Enzastaurin, 99%

CAS: 170364-57-5 Molecular Formula: C32H29N5O2,C32H29N5O2 Synonym: LY317615; 3-(1-Methyl-1H-indol-3-yl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione

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Specifications

CAS	170364-57-5
Synonym	LY317615; 3-(1-Methyl-1H-indol-3-yl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione
Molecular Formula	C32H29N5O2,C32H29N5O2

Thermo Scientific Chemicals C6 Ceramide

CAS: 124753-97-5 Molecular Formula: C24H47NO3,C24H47NO3 Synonym: N-Hexanoyl-D-erythro-sphingosine;

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Specifications

CAS	124753-97-5
Synonym	N-Hexanoyl-D-erythro-sphingosine;
Molecular Formula	C24H47NO3,C24H47NO3

Thermo Scientific Chemicals Autophagy Inhibitor, 3-MA

CAS: 5142-23-4 Molecular Formula: C₆H₇N₅,C6H7N5 Synonym: 3-Methyladenine; 6-Amino-3-methylpurine

Pricing & Availability
Specifications

CAS	5142-23-4
Synonym	3-Methyladenine; 6-Amino-3-methylpurine
Molecular Formula	C₆H₇N₅,C6H7N5

Thermo Scientific Chemicals Sulindac Sulfide

CAS: 32004-67-4 Molecular Formula: C₂₀H₁₇FO₂S,C20H17FO2S Molecular Weight (g/mol): 340.41 MDL Number: MFCD00869764 InChI Key: LFWHFZJPXXOYNR-RQZCQDPDSA-N IUPAC Name: 2-[(1E)-5-fluoro-2-methyl-1-{[4-(methylsulfanyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid SMILES: CSC1=CC=C(\C=C2/C(C)=C(CC(O)=O)C3=CC(F)=CC=C23)C=C1

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Specifications

CAS	32004-67-4
Molecular Weight (g/mol)	340.41
MDL Number	MFCD00869764
SMILES	CSC1=CC=C(\C=C2/C(C)=C(CC(O)=O)C3=CC(F)=CC=C23)C=C1
IUPAC Name	2-[(1E)-5-fluoro-2-methyl-1-{[4-(methylsulfanyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid
InChI Key	LFWHFZJPXXOYNR-RQZCQDPDSA-N
Molecular Formula	C₂₀H₁₇FO₂S,C20H17FO2S

Thermo Scientific Chemicals Bis(methylthio)gliotoxin, 99%

CAS: 74149-38-5 Molecular Formula: C15H20N2O4S2,C15H20N2O4S2 Molecular Weight (g/mol): 356.46 InChI Key: OVBAGMZLGLXSBN-UOVKNHIHSA-N Synonym: FR-49175; IUPAC Name: (3R,5aS,6S,10aR)-6-hydroxy-3-(hydroxymethyl)-2-methyl-3,10a-bis(methylsulfanyl)-1H,2H,3H,4H,5aH,6H,10H,10aH-pyrazino[1,2-a]indole-1,4-dione SMILES: CS[C@@]12CC3=CC=C[C@H](O)[C@H]3N1C(=O)[C@@](CO)(SC)N(C)C2=O

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Specifications

CAS	74149-38-5
Molecular Weight (g/mol)	356.46
SMILES	CS[C@@]12CC3=CC=C[C@H](O)[C@H]3N1C(=O)[C@@](CO)(SC)N(C)C2=O
Synonym	FR-49175;
IUPAC Name	(3R,5aS,6S,10aR)-6-hydroxy-3-(hydroxymethyl)-2-methyl-3,10a-bis(methylsulfanyl)-1H,2H,3H,4H,5aH,6H,10H,10aH-pyrazino[1,2-a]indole-1,4-dione
InChI Key	OVBAGMZLGLXSBN-UOVKNHIHSA-N
Molecular Formula	C15H20N2O4S2,C15H20N2O4S2

Thermo Scientific Chemicals Calmidazolium Chloride

CAS: 57265-65-3 Molecular Formula: C31H23Cl7N2O,C31H24Cl7N2O Molecular Weight (g/mol): 688.70 InChI Key: LBFGPQFQXRJXDI-UHFFFAOYNA-N IUPAC Name: 1-[bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-2,3-dihydro-1H-imidazole hydrochloridyl SMILES: [Cl].ClC1=CC=C(C=C1)C(N1CN(CC(OCC2=CC=C(Cl)C=C2Cl)C2=CC=C(Cl)C=C2Cl)C=C1)C1=CC=C(Cl)C=C1

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Specifications

CAS	57265-65-3
Molecular Weight (g/mol)	688.70
SMILES	[Cl].ClC1=CC=C(C=C1)C(N1CN(CC(OCC2=CC=C(Cl)C=C2Cl)C2=CC=C(Cl)C=C2Cl)C=C1)C1=CC=C(Cl)C=C1
IUPAC Name	1-[bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-2,3-dihydro-1H-imidazole hydrochloridyl
InChI Key	LBFGPQFQXRJXDI-UHFFFAOYNA-N
Molecular Formula	C31H23Cl7N2O,C31H24Cl7N2O

Thermo Scientific Chemicals Z-Leu-Glu(OMe)-His-Asp(OMe)-fluoromethyl ketone trifluoroacetate salt hydrate

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Thermo Scientific Chemicals Aurora Kinase/Cdk Inhibitor

CAS: 443797-96-4 Molecular Formula: C15H12F2N6O3S.CH3CN,C15H12F2N6O3S Molecular Weight (g/mol): 394.36 InChI Key: KDKUVYLMPJIGKA-UHFFFAOYSA-N Synonym: 4-(5-Amino-1-(2,6-difluorobenzoyl)-1H-[1,2,4]triazol-3-ylamino)-benzenesulfonamide; IUPAC Name: 4-{[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino}benzene-1-sulfonamide SMILES: NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=O)C1=C(F)C=CC=C1F

Pricing & Availability
Specifications

CAS	443797-96-4
Molecular Weight (g/mol)	394.36
SMILES	NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=O)C1=C(F)C=CC=C1F
Synonym	4-(5-Amino-1-(2,6-difluorobenzoyl)-1H-[1,2,4]triazol-3-ylamino)-benzenesulfonamide;
IUPAC Name	4-{[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino}benzene-1-sulfonamide
InChI Key	KDKUVYLMPJIGKA-UHFFFAOYSA-N
Molecular Formula	C15H12F2N6O3S.CH3CN,C15H12F2N6O3S

Thermo Scientific Chemicals Calpain Inhibitor II, 95+%

CAS: 136632-32-1 Molecular Formula: C₁₉H₃₅N₃O₄S,C19H35N3O4S Synonym: N-Ac-Leu-Leu-Methioninal; ALLM

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Specifications

CAS	136632-32-1
Synonym	N-Ac-Leu-Leu-Methioninal; ALLM
Molecular Formula	C₁₉H₃₅N₃O₄S,C19H35N3O4S

Thermo Scientific Chemicals Isotetrandrine, 98%

CAS: 477-57-6 Molecular Formula: C38H42N2O5,C38H42N2O6 Molecular Weight (g/mol): 622.76 InChI Key: WVTKBKWTSCPRNU-UHFFFAOYNA-N Synonym: Berbamine methyl ether; 6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman IUPAC Name: 9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2³,⁶.1⁸,¹².1¹⁴,¹⁸.0²⁷,³¹.0²²,³³]hexatriaconta-3,5,8(34),9,11,18,20,22(33),24(32),25,27(31),35-dodecaene SMILES: COC1=CC=C2CC3N(C)CCC4=CC(OC)=C(OC)C(OC5=CC6=C(CCN(C)C6CC6=CC=C(OC1=C2)C=C6)C=C5OC)=C34

Pricing & Availability
Specifications

CAS	477-57-6
Molecular Weight (g/mol)	622.76
SMILES	COC1=CC=C2CC3N(C)CCC4=CC(OC)=C(OC)C(OC5=CC6=C(CCN(C)C6CC6=CC=C(OC1=C2)C=C6)C=C5OC)=C34
Synonym	Berbamine methyl ether; 6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman
IUPAC Name	9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2³,⁶.1⁸,¹².1¹⁴,¹⁸.0²⁷,³¹.0²²,³³]hexatriaconta-3,5,8(34),9,11,18,20,22(33),24(32),25,27(31),35-dodecaene
InChI Key	WVTKBKWTSCPRNU-UHFFFAOYNA-N
Molecular Formula	C38H42N2O5,C38H42N2O6

Thermo Scientific Chemicals Bopindolol malonate, 97+%

CAS: 62658-64-4 Molecular Formula: C23H28N2O3.C3H4O4,C26H32N2O7 Molecular Weight (g/mol): 484.55 InChI Key: LDOONRJGLKHGJI-UHFFFAOYNA-N IUPAC Name: 1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl benzoate; propanedioic acid SMILES: OC(=O)CC(O)=O.CC1=CC2=C(OCC(CNC(C)(C)C)OC(=O)C3=CC=CC=C3)C=CC=C2N1

Pricing & Availability
Specifications

CAS	62658-64-4
Molecular Weight (g/mol)	484.55
SMILES	OC(=O)CC(O)=O.CC1=CC2=C(OCC(CNC(C)(C)C)OC(=O)C3=CC=CC=C3)C=CC=C2N1
IUPAC Name	1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl benzoate; propanedioic acid
InChI Key	LDOONRJGLKHGJI-UHFFFAOYNA-N
Molecular Formula	C23H28N2O3.C3H4O4,C26H32N2O7

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