Thermo Scientific Chemicals SR-12813, 98%

Description

CAS: 126411-39-0 | C24H42O7P2, C24H42O7P2 | 504.54 g/mol

R-12813 was used as control in pregnane X receptor (PXR) binding assay performed in HepG2 liver carcinoma cells and PXR-activation assay mediated by dehydroepiandrosterone in human hepatocytes. It decreases the biosynthesis of cholesterol by enhancing the degradation of HMG-CoA reductase. This compound is a featured product for Gene Regulation research.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 126411-39-0
• Molecular Formula: C24H42O7P2
• Molecular Weight (g/mol): 504.54
• InChI Key: YQLJDECYQDRSBI-UHFFFAOYSA-N
• Synonym: Tetraethyl 2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethenyl-1,1-bisphosphonate;
• IUPAC Name: diethyl [2-(3,5-di-tert-butyl-4-hydroxyphenyl)-1-(diethoxyphosphoryl)ethenyl]phosphonate
• SMILES: CCOP(=O)(OCC)C(=CC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C)P(=O)(OCC)OCC

• Quantity: 10 mg
• Description: White
• Formula Weight: 504.54
• Melting Point: 119°C to 121°C
• Solubility: Soluble in DMSO at 25mg/ml
• Product Type: SR-12813, 98%
• Form: Solid
• Assay: 98%

Safety and Handling

Recommended Storage

Ambient temperatures

SDS

RUO – Research Use Only