Signal Transduction Reagents and Kits
Thermo Scientific™ Tulobuterol
beta-2-adrenergic receptor agonist
Thermo Scientific Chemicals NF-kB Activation Inhibitor VI, BOT-64
CAS: 113760-29-5 Molecular Formula: C15H15NO2S,C15H15NO2S Synonym: (Z)-6,6-Dimethyl-2-(phenylimino)-6,7-dihydrobenzo[d][1,3]oxathiol-4(5H)-one
Thermo Scientific™ Veratridine, ≥97%
Activates sodium ion channels
Thermo Scientific Chemicals Loxistatin
CAS: 88321-09-9 Molecular Formula: C17H30N2O5,C17H30N2O5 Synonym: EST; E-64d
Promega Cell Permeable Inhibitors
LY 294002 is a potent and specific cell-permeable inhibitor of phosphatidylinositol 3-kinases (PI 3-kinases).
Promega P450-Glo CYP2B6 Assay, 50ml
The P450-Glo Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays
Cayman Chemical Thiol Detection Assay Kit, 96 wells
The detection and measurement of free thiols (i.e., free cysteine, glutathione, and cysteine residues on proteins) is one of the essential tasks for investigating biological processes and events in many biological systems. Cayman’s Thiol Detection provides a simple, reproducible, and sensitive tool for assaying free thiol content in samples (i.e., plasma, serum, tissue homogenates, cell lysates, and urine). The assay utilizes a proprietary fluorometric detector that reacts with thiol groups to emit a strong fluorescent signal which can be detected using excitation wavelengths between 380-390 nm and emission wavelengths between 510-520 nm.
Cayman Chemical Thiol Detection Assay Kit, 480 wells
The detection and measurement of free thiols (i.e., free cysteine, glutathione, and cysteine residues on proteins) is one of the essential tasks for investigating biological processes and events in many biological systems. Cayman’s Thiol Detection provides a simple, reproducible, and sensitive tool for assaying free thiol content in samples (i.e., plasma, serum, tissue homogenates, cell lysates, and urine). The assay utilizes a proprietary fluorometric detector that reacts with thiol groups to emit a strong fluorescent signal which can be detected using excitation wavelengths between 380-390 nm and emission wavelengths between 510-520 nm.
Cayman Chemical Glycerol Colorimetric Assay Kit, 96 wells
Glycerol is the backbone of triglycerides and an important intermediate in energy metabolism being involved in both oxidative and synthetic processes. The circulating levels of glycerol and free fatty acids are considered to reflect lipolysis and are therefore useful parameters to evaluate in various conditions. The measurement of glycerol is also useful for correction of glycerol interference when measuring triglycerides in reference materials and in serum from patients with elevated glycerol concentrations. Cayman’s Glycerol Assay provides a simple, reproducible, and sensitive tool for measurement of glycerol in plasma and serum. The assay employs a coupled enzymatic reaction system that yields a brilliant purple product with an absorbance maximum at 540 nm.
Cayman Chemical YM-53601, 182959-33-7, 500 µg
Inhibits squalene synthase activity in rat hepatic microsomes and human Hep-G2 cells (IC50 values of 90 and 79 nM, respectively); inhibits cholesterol biosynthesis in rats reducing both cholesterol and triglyceride levels in plasma