Microspheres
Electron Microscopy Sciences EMS Oscillating Tissue Slicer Large Tissue Pedestal Replacement Surface Only
Replacement part for EMS 4000 oscillating tissues slicer.
Abcam Fluorescein-5-thiosemicarbazide, Fluorescent tag, 500MG
MW 421.43 g/mol, Purity >97%. Fluorescent tag for labeling of cell-surface functional groups (glycophorins). Also used as a probe for detecting protein carbonyl derivatives.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Fluorescein-5-thiosemicarbazide, Fluorescent tag, 100MG
MW 421.43 g/mol, Purity >97%. Fluorescent tag for labeling of cell-surface functional groups (glycophorins). Also used as a probe for detecting protein carbonyl derivatives.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical JWH 019 N- 5-hydroxyhexyl me
A potential urinary metabolite of AKB48 characterized by carboxylation of the N-alkyl chain intended for research and forensic applications
Cayman Chemical JWH 018 benzimidazole analog
A 4-demethoxy analog of daunorubicin which intercalates in DNA and inhibits topoisomerase II resulting in cancer cell cytotoxicity at low concentrations (IC50 20-120 nM) effective in combination therapy for the treatment of different types of leukemia
Cayman Chemical JWH 019 N 5hydroxyhexyl me 5mg
PGE2 p-acetamidophenyl ester is a crystalline derivative of PGE2. PGE2 is one of the primary COX products of arachidonic acid and one of the most widely investigated PGs. Its activity influences inflammation fertility and parturition gastric mucosal integrity and immune modulation.{158515584371330} The effects of PGE2 are transduced by at least four distinct receptors designated EP1 EP2 EP3 and EP4.{1422} Affinity constants (Kd) of PGE2 for these receptors range from 1-10 nM depending on the receptor subtype and tissue.
Cayman Chemical PAMAM Dendrimer G1 5 Carboxyl
An active metabolite of various polyphenols an inhibitor of MMP-1 and MMP-2 collagen degradation activity (IC50s 108 and 106 nM respectively) MMP-1 and MMP-9 gelatin degradation activity (IC50s 45.2 and 17.7 nM respectively) and MMP-2 and MMP-9 elastin degradation activity (IC50s 61.8 and 89 nM respectively) scavenges free radicals in a TEAC assay
Cayman Chemical EOPt18 028 018 2-d11 100UG
A TNNI3K inhibitor and sorafenib derivative (IC50 10 nM) selective for TNNI3K over VEGFR2 p38a and B-RAF (IC50s 400 800 and >2000 nM respectively) reduces superoxide levels in isolated left ventricular tissues and infarct size in a mouse model of myocardial ischemia-reperfusion injury induced by LAD coronary artery occlusion at 2.75 mg/kg
Cayman Chemical JWH 018 N- 5-hydroxypentyl m
A protected L-tyrosine derivative has been used in the synthesis of peptides and antibacterial-peptide conjUGates
Cayman Chemical JWH 018 N 5hydroxypentyl m
A selective inhibitor of 6 desaturase (IC50 0 2 UM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to AA orally active in vivo decreasing edema in the carrageenan paw edema model in mice
Cayman Chemical Fluorescent BrIghtenr 28 5g
A neutral lipid has been used in the generation of LNPs intravenous administration of LNPs containing DNCA and encapsulating siRNA targeting BRAFV600E reduce tumor BRAFV600E expression and tumor weight and volume without reducing animal weight in an A375 melanoma mouse xenograft model intratumoral administration of LNPs containing DNCA and encapsulating cyclic di-GMP decreases tumor volume increase survival and increase the ratio of tumor-associated cytotoxic/exhausted CD4 and CD8 T cells in an EO771 murine model of primary breast cancer with tumor rechallenge
Cayman Chemical Fluorescent BrIghtenr 28 1g
An inhibitor of mRNA-capping enzyme subunit B (IC50 2 UM for the GTPase activity of the S. cerevisiae enzyme) activates E. coli aspartate carbamoyltransferase (EC50 0.76 mM) has been used in the synthesis of cytokinins with anticancer activity and a photoclickable form of ATP
Cayman Chemical BIotInyl TyramIde 25mg
An internal standard for the quantification of captopril by GC- or LC-MS