Modifying Enzymes
BIOTIUM INC Topoisomerase I, MT(TOP1MT/488), CF740 conjugate, 0.1mg/mL
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can
ALKALI SCIENTIFIC INC Radiant™ HiFi Pro™ Hot Start Enzyme, 2u/ul with 5X Buffer, 100 Reactions, with Enhancer Juice
Radiant™ HiFi Pro™ Hot Start Enzyme, 2u/ul with 5X Buffer, 100 Reactions, with Enhancer Juice, provides excellent amplification capabilities for high-fidelity PCR. This enzyme system is designed for precise and reliable DNA amplification with minimal errors. The 5X buffer ensures optimal reaction conditions, while the enhancer juice improves amplification efficiency, making it perfect for difficult templates. It is ideal for researchers who require high-quality results in a variety of PCR applications.
ALKALI SCIENTIFIC INC Radiant™ HiFi Pro™ Enzyme, 2u/ul with 5X Buffer, 500 Reactions, with Enhancer Juice
Radiant™ HiFi Pro™ Enzyme, 2u/ul with 5X Buffer, is designed for high-fidelity PCR, providing accurate amplification with minimal error rates. With 500 reactions, this product ensures high performance across large-scale experiments. The 5X buffer and enhancer juice optimize enzyme activity, ensuring high yield and consistency. This enzyme is ideal for applications requiring precision and reliability, delivering superior performance for demanding PCR assays.
ALKALI SCIENTIFIC INC Radiant™ HiFi Pro™ Enzyme, 2u/ul with 5X Buffer, 100 Reactions, with Enhancer Juice
Radiant™ HiFi Pro™ Enzyme, 2u/ul with 5X Buffer, offers high-fidelity amplification for PCR applications. This enzyme is designed to minimize errors and improve amplification accuracy, making it ideal for critical experiments. With a 5X buffer and enhancer juice, it enhances enzyme efficiency, ensuring robust performance in complex PCR assays. Suitable for a wide range of research applications, it provides consistent, high-quality results.
SINO BIOLOGICAL US INC Recombinant DNase I (RNase-free) 1000 U
DNase I is an endonuclease that can non-specifically cleave DNA, producing dinucleotide, trinucleotide, and oligonucleotide products with 5 ́ phosphorylated and 3 ́ hydroxylated ends. DNase I acts on single-and double-stranded DNA, chromatin, and RNA:DNA hybrid strands. Certified by highly sensitive fluorescence probe assays, our DNase I (RNase-free) demonstrates virtually undetectable RNase activity-a level of purity that surpasses other commercial sources. Trust in this "Ultra-Pure" standard for the ultimate reliability in your RNase-sensitive workflows.
SINO BIOLOGICAL US INC Recombinant DNase I (RNase-free) 5000 U
DNase I is an endonuclease that can non-specifically cleave DNA, producing dinucleotide, trinucleotide, and oligonucleotide products with 5 ́ phosphorylated and 3 ́ hydroxylated ends. DNase I acts on single-and double-stranded DNA, chromatin, and RNA:DNA hybrid strands. Certified by highly sensitive fluorescence probe assays, our DNase I (RNase-free) demonstrates virtually undetectable RNase activity-a level of purity that surpasses other commercial sources. Trust in this "Ultra-Pure" standard for the ultimate reliability in your RNase-sensitive workflows.
APEXBIO TECHNOLOGY LLC E.-COLI-DNA-LIGASE-200U
E coli DNA ligase is an enzyme used extensively in molecular biology research particularly within the fields of genetic engineering and biotechnology Originating from the bacterium Escherichia coli this enzyme plays a crucial role in DNA replication and repair by catalyzing the formation of phosphodiester bonds between the 3 -hydroxyl and 5 -phosphate ends of DNA fragments Its mechanism of action involves the joining of Okazaki fragments on the lagging strand during DNA replication as well as sealing nicks in the DNA backbone It exhibits high activity in in vitro applications typically within the nanomolar to low micromolar range E coli DNA ligase is commonly used in applications involving cell models animal studies and drug screening protocols where its ability to ligate DNA fragments is essential Experimental concentrations typically depend on the specific research design allowing for flexibility in various experimental setups
