Modifying Enzymes
Apexbio Technology LLC Lambda Exonuclease(Synonyms: Lambda Exo, Lambda exonuclease enzyme, λ exonuclease, λ exonuclease enzyme), 5000U.
Lambda Exonuclease is a DNA-specific exonuclease enzyme that progressively degrades double-stranded DNA in a 5 3 direction preferentially initiating digestion at 5 -phosphorylated termini It displays minor activity toward single-stranded DNA and double-stranded DNA with non-phosphorylated ends but cannot start cleavage at internal nicks or gaps Lambda Exonuclease is commonly employed in molecular biology laboratories for the generation of single-stranded DNA templates DNA single-strand conformation polymorphism (SSCP) analysis selective degradation of linear plasmid forms while preserving supercoiled structures and rolling-circle amplification protocols
Medchemexpress LLC Lipase from Pseudomonas fluorescens (immobilized) | 9001-62-1 | MFCD00131509 | 1g
Lipase Pseudomonas fluorescens (Immobilized) comes from Pseudomonas fluorescens and shows good applicability in ester synthesis of food industry the biofuel synthesis the synthesis of enantiomeric pure chiral drugs and so on[1]
Echelon Biosciences Research Labs GLO-PI(3,4,5)P3 BODIPYTMR50ug
BODIPY TMR PI(3,4,5)P3 (BODIPY TMR Phosphatidylinositol 3,4,5-trisphosphate) is a water soluble analog of PI(3,4,5)P3 (PIP3) labeled with the orange fluorophore, Bodipy-TMR, at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. This item is non returnable
Carnabio Usa Inc WNK2/10UG/CATALYTIC
WNK2, Catalytic domain, Wild type, Amino Acid 166-489, NP_006639.3, Expressed in Insect (sf21); 10microg
Carnabio Usa Inc AMPKA1/B1/G1(PRKAA1/B1/G1)/10U
AMPK1/1/1(PRKAA1/B1/G1), Full-length, Wild type, Amino Acid 1-550, NP_006242.4, Expressed in Insect (sf21); 10microg
LifeSensors USP15 25µg
USP15 (Ubiquitin Specific Protease 15, UNPH4) is a deubiquitinase that associates with the COP9 signalosome (CSN) complex. It regulates various pathways such as the TGF-beta receptor signaling, NFκB and RNF41/NRDP1-PRKN pathways.
ABclonal Technology T7 DNA Ligase
T7 DNA Ligase is an ATP-dependent ds DNA ligase from bacteriophage T7. It can catalyze the formation of a phosphodiester bond between adjacent 5 phosphate and 3 hydroxyl termini in double-stranded DNA. T7 DNA ligase can catalyze ligation of cohesive ends and repair nicks, but not blunt end ligation. This makes a good choice for applications in which blunt and cohesive ends of DNA are present but only the cohesive ends are to be joined .
ABclonal Technology T4 RNA Ligase 1
T4 RNA ligase 1 catalyzes the formation of a 3 to 5 phosphodiester bond by joining the 5 phosphate end of a nucleotide to the 3 hydroxyl end, accompanied by the hydrolysis of ATP to AMP and PPi. Substrates include single-stranded RNA, DNA, and dinucleoside pyrophosphates.
ABclonal Technology Endonuclease III (Nth)
Endonuclease III (Nth) protein acts as both N-glycosylase and a AP-lyase.The N-glycosylase activity releases damaged pyrimidines from double-stranded DNA, generating a basic (AP site). The AP-lyase activity of the enzyme cleaves 3? to the AP site leaving a 5? phosphate and a 3? ring opened sugar.
Cayman Chemical N-Oleoyl ValIn 50mg
An endogenous N-acyl amine; antagonist at TRPV3; increases after acute lung injury in mouse lung tissue
Selleck Chemical LLC Cabozantinib (BMS-907351) 200mg 849217-68-1 XL184
Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3?/NF-?B signaling pathway. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences PARP-1 (catalytic domain) (human), (recombinant) (His-tag) (20µg)
Alternative name: Poly(ADP-ribose) polymerase 1. Purity: ≥90% (SDS-PAGE). MW: ~46kDa. Formulation: Liquid. In 50mM TRIS-HCl, pH 7.5, containing 300mM sodium chloride, 250mM imidazole, 2mM β-mercaptoethanol, 0.2% NP-40 and 10% glycerol. Source: Produced in SF21 insect cells. Human PARP-1 (aa 656-1014) is fused to a C-terminal His-tag. Produced in a baculovirus expression system. Long Term Storage: -80°C. Handling: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.
Cayman Chemical EthylmaLNyl Coenzyme AsodI 5mg
An intermediate in the ethylmalonyl-CoA pathway in bacteria
Medchemexpress LLC α-Amylase from Aspergillus oryzae | 9001-19-8 | ≥100 U/mg solid | 25 G
Alpha-Amylase from Aspergillus oryzae is an amylase primarily utilized in various biochemical studies. This enzyme functions to liquefy soluble starch into dextrin, with a defined activity indicating its potency and effectiveness for experimental applications.
- Can be used for various biochemical studies.
- Enzyme activity is equal to or greater than 100 U/mg solid.
- One unit liquefies 1mg of soluble starch into dextrin in one minute at 70°C and pH 6.0.
- Appearance is solid, white to off-white.
- Ships at room temperature in continental US.
- Store under recommended conditions in the Certificate of Analysis.
Carnabio Usa Inc BTN - TGFBR1(TGFBR1) / 10UG
BTN-TGFR1(TGFBR1), Catalytic domain, Wild type, Amino Acid 200-503(end), NP_004603.1, Expressed in Insect (sf21); 10microg