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Systematic combinations of a large variety of peptides manufactured to customer specifications; can be used for target screening in research areas such as immunotherapy, vaccine development, drug discovery, and proteomics.
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SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases The spike protein mutation N501Y is one of six key contact residues within the receptor-binding domain (RBD) and has been identified as increasing binding affinity to human and murine ACE2
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BA 2 differs from BA 1 in its genetic sequence including some amino acid differences in the spike protein and other proteins Studies have shown that BA 2 has a growth advantage over BA 1 Studies are ongoing to understand the reasons for this growth advantage but initial data suggest that BA 2 appears inherently more transmissible than BA 1 which currently remains the most common Omicron sublineage reported This difference in transmissibility appears to be much smaller than for example the difference between BA 1 and Delta Further although BA 2 sequences are increasing in proportion relative to other Omicron sublineages (BA 1 and BA 1 1) there is still a reported decline in overall cases globally
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SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases As of May 2021 three sublineages have been found Despite its name B 1 617 3 was the first sublineage of this variant to be detected in October 2020 in India This sublineage has remained relatively uncommon compared to the two other sublineages B 1 617 1 (also known as variant Kappa) and B 1 617 2 (also known as variant Delta) both of which were first detected in December 2020 This variant has the double mutations E484Q and L452R in the spike proteins Emerging research suggests the variant may be more transmissible than previously evolved ones Whether the effectiveness of currently-deployed vaccines is affected remains under investigation Moreover the sublineage B 1 617 2 has been redesignated as variant of concern (VOC-21APR-02) in May 2021 which spreads more quickly than the origin
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Immunogen Fusion protein from the cytoplasmic loop of the Y2 subunit of the rat GABAA receptor Host Rabbit Species Reactivity ( ) Mouse rat Applications IHC WB MW 46 kDa
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A fatty acid ester; has been used in the manufacture of plastics, moldable flame-retardant resin compositions, and as a component of antifouling paint; can migrate out of plastics but is not toxic to rats during prenatal development at 900 mg/kg per day
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019 (COVID-19) the respiratory illness responsible for the COVID-19 pandemic SARS-CoV-2 also known as 2019-nCoV is a positive-sense single-stranded RNA virus and is believed to have zoonotic origins and has close genetic similarity to bat coronaviruses The receptor binding domain (RBD) of spike protein of the SARS-CoV-2 virus binds Angiotensin-Converting Enzyme 2 (ACE2) to invade the host cells Based on structural biology studies the RBD can be oriented either in the up/standing or down/lying state with the up/standing state associated with higher pathogenicity
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