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Systematic combinations of a large variety of peptides manufactured to customer specifications; can be used for target screening in research areas such as immunotherapy, vaccine development, drug discovery, and proteomics.
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A dual inhibitor of PI3K and mTOR (IC50s 3 4 12 16 and 16 nM for PI3Ka PI3KB PI3K and PI3KY respectively) inhibits proliferation of PC3 and MCF-7 1 cells (IC50s 330 and 180 nM respectively) reduces tumor volume in PC3 and MCF-7 1 mouse xenograft models at 10 mg/kg per day
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
HPV16 E7 is a viral phosphoprotein with oncogenic activity belonging to the human papillomavirus early protein family HPV16 E7 activates the cell cycle by releasing E2F through proteasome degradation of pRB HPV16 E7 can cooperate with E6 to immortalize cells and neutralize the toxicity of E5 while activating the AP-1/NF- B pathway and downregulating E-cadherin to enhance migration and invasion making it a core target for cervical cancer Protein E7 HPV (His) is a recombinant HPV E7 protein expressed from E coli with an N-6 His tag
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More