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Arrays of numerous spots containing specific oligonucleotides, DNA, proteins, peptides or other small molecules chemically attached to a substrate and organized in a grid on a supporting material; probe-based technique used in biochemistry and genetics.
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Ubiquitination plays a key role in protein degradation and signal transduction. Characterization of ubiquitination sites is important for understanding the role of this modification in cellular processes and disease. Ubiquitination sites are usually identified by detection of Lys-?-Gly-Gly (K-?-GG)-remnant peptides, which are generated by tryptic digestion of proteomes. The di-glycine remnant left at sites of ubiquitination after trypsin digestion through cleavage of the C-terminal –RGG sequence on ubiquitin (K-ε-GG). This Ubiquitin K-ε-GG remnant motif antibody will recognize the di-glycine remnant independent of flanking amino acid sequence.
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RayBio C-Series Human Cytokine Antibody Array 1000 Kit. A combination of Human Cytokine Antibody Array C6 & C7. Detects 120 Human Cytokines. Suitable for all liquid sample types.
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Ubiquitin-K29R is recombinant ubiquitin with a single substitution of arginine for lysine at position 29. Notable, ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Ubiquitin moieties can subsequently be conjugated to this initial ubiquitin. This utilizes any one (of seven) lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation. This mutation will ensure chains will not form at mutated lysine to arginine peptide and if mutation causes any functional differences. Need assistance with our products? Contact us here at customerservice@lifesensors.com.
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This probe has Carbon Fiber support with -28 fittings and a capillary length of 100 cm (after probe). This SC FAST Probe is included in the MicroFAST Line Valve Complete Assembly (N8150400).
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StabilCoat™ Plus Stabilizer protects the activity of proteins while simultaneously blocking nonspecific binding sites on microspheres. In microarray applications, the conformation and activity of proteins are effectively preserved in a dried state when stored with StabilCoat™ Plus stabilizer. The product ultimately increases signal and reduces background to improve the sensitivity of assays.
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