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Medchemexpress, HY-101969 5mg Pseudothymidine CAS:65358-15-8 Pseudothymidine is a C-nucleoside analog of thymidine. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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A purine nucleoside analog; reduces infection of Calu-3 cells by SARS-CoV-2 (EC50 = 0.04 µM) but is also toxic to Calu-3 cells (CC50 = 1.14 µM); decreases tumor volume and increases the number of tumor cells with telomere dysfunction-induced foci in an A549 NSCLC mouse xenograft model at 2 mg/kg; increases the number of PD-1+ CD8+ T cells, as well as induces tumor regression when administered in combination with anti-PD-L1 in MC-38 murine colon carcinoma models
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5-Aminoallyl-dUTP can be enzymatically incorporated into DNA. The resulting amine-containing DNA can be subsequently labeled with a fluorescent dye, biotin or other haptens via conventional peptide coupling method. This two-step method for labeling nucleic acids is considerably more economical than the one-step method using a prelabeled dUTP. The lyophilized powder form of 5-Aminoallyl-dUTP is suitable for long-term storage. Properties: White solid soluble in water; Store at -20⁰C; C12H17N3Na3O14P3; MW: 589.17.
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