Nucleic Acid Synthesis
Chem-Impex International, Inc. Thymidine | 50-89-5 | MFCD00006537 | 100G
Thymidine, 50-89-5, MFCD00006537, 100G
Chem-Impex International, Inc. Guanosine-5'-monophosphate disodium salt | 5550-12-9 | MFCD00070575 | 100G
Guanosine-5'-monophosphate disodium salt, 5550-12-9, MFCD00070575, 100G
Cayman Chemical Indole-3-thIo CarboxamIde 1g
A synthetic intermediate useful for pharmaceutical synthesis
![Alkali Scientific FUDR [5 Fluoro 2' deoxyuridine], 5 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660298.jpg-250.jpg)
Alkali Scientific FUDR [5 Fluoro 2' deoxyuridine], 5 G
Fudr (5-Fluoro-2′-deoxyuridine) is a potent nucleoside analog used in DNA synthesis inhibition and cancer research. This 5g quantity is suitable for larger-scale experiments and is commonly used to study the effects of DNA replication interference in cultured cells. Fudr mimics uracil and gets incorporated into DNA, disrupting DNA synthesis and leading to cell cycle arrest. It is widely used in cancer research to evaluate the effectiveness of fluoropyrimidine-based chemotherapy. The 5g package is ideal for labs requiring higher quantities for screening, treatment studies, and in-depth analysis of cancer cell biology and nucleotide metabolism.
Alkali Scientific Guanosine, 5 Grams
Guanosine is a purine nucleoside composed of the nitrogenous base guanine attached to a ribose sugar. It is a crucial component of RNA and is involved in various biochemical pathways, including nucleotide metabolism and cell signaling. This 5g format of guanosine is commonly used in molecular biology and biochemical research. It serves as a building block for RNA synthesis and is essential for studies involving RNA structure and function. Guanosine is also used in the study of enzymatic reactions, nucleotide binding, and in the design of nucleotide analogs for therapeutic research. It plays a pivotal role in studies on signal transduction and energy transfer.
Apexbio Technology LLC 6-Thio-dG 789-61-7 5mg
6-Thio-2 -deoxyguanosine (6-Thio-dG CAS 789-61-7) is a nucleoside analogue that functions as a telomerase-mediated telomere targeting agent In telomerase-positive cancer cells 6-Thio-dG is incorporated into telomeric DNA inducing rapid telomere dysfunction independent of direct telomerase inhibition which leads to growth arrest and cell death In vitro cancer cell lines exhibit IC50 values ranging from 0 7 to 2 9 M indicating high sensitivity to the compound Normal cells with telomerase-silent status show minimal morphological effects upon 6-Thio-dG exposure In vivo 6-Thio-dG administration inhibits tumor growth and reduces proliferation markers in xenograft models The compound is valuable for investigating telomere biology and as a tool to evaluate telomerase-dependent therapeutic strategies in cancer research
Medchemexpress LLC Nucleoside-Analog-1 | 876707-99-2 | >95.0% | C9H9N5O5 | 50 MG
Nucleoside-Analog-1 is a click chemistry reagent containing an azide group. It can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups, and in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Click chemistry reagent containing an azide group.
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Sigma Aldrich Fine Chemicals Biosciences Adefovir dipivoxil | 142340-99-6 | MFCD00869897 | 50MG
Adefovir dipivoxil | Purity: >=98% (HPLC) | Mol Wt: 501.47 | 142340-99-6 | MFCD00869897 | 50MG
Medchemexpress LLC Purine nucleoside phosphorylase (human), His-tagged recombinant protein | 9030-21-1 | 50 UG
Recombinant human purine nucleoside phosphorylase (PNP) with a histidine tag supplied as a purified protein for laboratory research. The protein is intended for enzymology, biochemical assays, structural studies, and related experimental applications where a human PNP reagent is required.
- Recombinant human PNP with a His tag.
- Supplied as purified protein for research use.
- Suitable for enzymatic assays and activity studies.
- Useful for structural biology and protein-ligand interaction experiments.
- Available in small research sizes such as 50 μg.
- Provided with product documentation such as datasheet or certificate of analysis.
Cambridge Isotope Laboratories 5-Methyluridine 5-triphosphate ammonium salt (ribose-1 2 3 4 5-13C5 99%) (in solution) CP 95% 100 umol
5-Methyluridine 5-triphosphate ammonium salt (ribose-1 2 3 4 5-13C5 99%) (in solution) CP 95% 100 umol
Medchemexpress LLC 5-Methylcytidine 5′-triphosphate trisodium | 327174-86-7 | 99.6% | 563.13 | 28 MG
5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. It can be used to replace unmodified mRNA, which leads to an increase in translational properties and stability, and a reduction in innate immune responses in human and other mammalian cells.
- Increases translational properties
- Enhances stability of mRNA
- Reduces innate immune responses in mammalian cells
- For research use only
![eMolecules 10017-66-0 | Alpha-Pseudouridine | Broadpharm244.203 | C9H12N2O6 | 0.000 | OC[C@H]1O[C@@H]([C@H](O)[C@@H]1O)c1c[nH]c(=O)[nH]c1=O | 100mg | 761707695](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502459962.PNG-250.jpg)
eMolecules 10017-66-0 | Alpha-Pseudouridine | Broadpharm244.203 | C9H12N2O6 | 0.000 | OC[C@H]1O[C@@H]([C@H](O)[C@@H]1O)c1c[nH]c(=O)[nH]c1=O | 100mg | 761707695
Alpha-Pseudouridine | Broadpharm | 10017-66-0244.203 | C9H12N2O6 | 0.000 | OC[C@H]1O[C@@H]([C@H](O)[C@@H]1O)c1c[nH]c(=O)[nH]c1=O | 100mg | 761707695
Medchemexpress LLC 5-fluorocytidine | 2341-22-2 | MFCD00210953 | 97.0% | 261.21 g/mol | C9H12FN3O5 | 1 G
5-fluorocytidine is a fluorinated cytidine nucleoside that inhibits maturation of the 45S ribosomal RNA precursor and is provided as a characterized research reagent with storage and safety guidance from product datasheets and SDS.
- Fluorinated cytidine nucleoside.
- Inhibits maturation of the 45S ribosomal RNA precursor.
- Molecular formula C9H12FN3O5.
- Molecular weight 261.21 g/mol.
- Storage: 4°C under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month.
Sigma Aldrich Fine Chemicals Biosciences 4-Thiouridine >=98% | 13957-31-8 | MFCD00006538 | 100MG
4-Thiouridine >=98% | Purity: >=98% | Mol Wt: 260.27 | 13957-31-8 | MFCD00006538 | 100MG
Sigma Aldrich Fine Chemicals Biosciences Cytidine 5'-diphosphocholine sodium salt dihydrate ~98%, from yeast, solid | 33818-15-4 | MFCD00150508 | 500MG
Cytidine 5'-diphosphocholine sodium salt dihydrate ~98%, from yeast, solid | Purity: ~98% | Mol Wt: 546.34 | 33818-15-4 | MFCD00150508 | 500MG