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Fialuridine (FIAU) is a fluorinated, iodinated nucleoside analog with demonstrated antiviral activity supplied for laboratory research. The product is offered as a ready-to-use 10 mM solution in DMSO (1 mL) and as solid quantities for use in synthesis and biological testing.
Antiviral nucleoside analog active against hepatitis B virus and herpesviruses.
Supplied as 10 mM solution in DMSO (1 mL) for immediate use in assays.
Also available in multiple solid sizes for formulation or synthesis.
High reported purity (≈99.9%) suitable for research applications.
Molecular formula C9H10FIN2O5; molecular weight 372.09 Da.
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A purine nucleoside analog; reduces infection of Calu-3 cells by SARS-CoV-2 (EC50 = 0.04 µM) but is also toxic to Calu-3 cells (CC50 = 1.14 µM); decreases tumor volume and increases the number of tumor cells with telomere dysfunction-induced foci in an A549 NSCLC mouse xenograft model at 2 mg/kg; increases the number of PD-1+ CD8+ T cells, as well as induces tumor regression when administered in combination with anti-PD-L1 in MC-38 murine colon carcinoma models
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Nucleoside-Analog-1 is a click chemistry reagent containing an azide group. It can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules that have alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Click chemistry reagent with an azide group
Participates in copper-catalyzed azide-alkyne cycloaddition reactions
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Trifluridine is an irreversible and orally active thymidylate synthase inhibitor that suppresses DNA synthesis. It is an antiviral molecule and an anticancer agent, used in research for various infections and tumors.
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Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 21. purity: 99%
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A triterpenoid saponin with diverse biological activities binds to AB42 (Kd 27.63 UM) inhibits the invasion and migration of and induces apoptosis and cell cycle arrest at the G0/G1 phase in HeLa cervical cancer cells at 4 UM improves learning and memory in the Morris water maze in mice in the 3xTg model of Alzheimer’s disease at 10 mg/kg reduces neurological deficits lesion volume edema and microglia lesion infiltration in a mouse model of acute cerebral hemorrhage induced by intracerebral injection of bacterial collagenase VII
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Nucleoside-Analog-2 is a 4'-Azidocytidine analogue primarily designed to act against Hepatitis C virus (HCV) replication. It functions as a versatile click chemistry reagent, featuring an Azide group, which enables participation in both copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
Acts against hepatitis C virus (HCV) replication
Functions as a click chemistry reagent
Contains an azide group for CuAAc reactions with alkyne-containing molecules
Undergoes SPAAC reactions with DBCO or BCN group-containing molecules
Intended for research use only
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